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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
260 Results for "
Monocytes
" in MedChemExpress (MCE) Product Catalog:
Products (260)
260 Results for "Monocytes" in MCE Product Catalog:
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ACT-389949 is a first-in-class, potent and selective and agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. ACT-389949 has potential for the treatment of inflammatory disorders .
Synonyms: Fosinoprilat; Fosinoprilic acid; SQ 27519
Target:
Angiotensin-converting Enzyme (ACE) Toll-like Receptor (TLR) NF-κB TNF Receptor Interleukin Related
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Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes .
Cat. No.: HY-122767
CAS No.: 78113-36-7
Synonyms: Muroctasin
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Cat. No.: HY-P0308
CAS No.: 103213-49-6
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Synonyms: (S)-(-)-Nadifloxacin; WCK 771
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Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .
Cat. No.: HY-P99704
CAS No.: 1688648-13-6
Synonyms: OCS-02
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Cat. No.: HY-P5812
CAS No.: 1224095-25-3
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Synonyms: 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; 19:0 Lyso PC
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Lysophosphatidylcholine C19:0 (19:0 Lyso PC) is a lysophosphatidylcholine with a fully saturated C19 acyl chain. When combined with LPS (HY-D1056), Lysophosphatidylcholine C19:0 induces the secretion of IL-1β by human monocyte-derived dendritic cells. Lysophosphatidylcholine C19:0 reduces the viability of monocyte-derived dendritic cells .
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Cardiovascular Disease Neurological Disease Inflammation/Immunology
GSK2647544 is an orally available, selective inhibitor of Lp-PLA2. Lipoprotein-associated phospholipase (Lp-PLA2) is a calcium-independent phospholipase A2 with proinflammatory activities that is primarily secreted by monocyte-derived macrophages .
BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1, especially in monocyte-derived macrophages (EC50 is 2.25 μM), without significant cytotoxicity (TC50 is 284 μM) .
Cat. No.: HY-157939
CAS No.: 3054870-33-3
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GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis .
Cat. No.: HY-P2311
CAS No.: 120721-97-3
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Cat. No.: HY-14762
CAS No.: 141388-76-3
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Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity .
Cat. No.: HY-108661A
Purity: 97.4%
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NF546 (hydrate) is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 (hydrate) stimulates release of interleukin-8 from human monocyte-derived dendritic cells .
Cat. No.: HY-P3895A
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Cat. No.: HY-B0227S
CAS No.: 159490-55-8
Synonyms: RP-19583-d3
Cat. No.: HY-160197
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Aluminum phosphate adjuvant is a safe and effective adjuvant that activates immune system and immune system-related pathways in monocytes .
Cat. No.: HY-16384
CAS No.: 125228-51-5
Synonyms: Antibiotic L 156602; PD 124966
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L-156602 is a C5a receptor antagonist. L-156602 inhibits inflammation, and the migration of monocytes and neutrophils to the infiltrating site in mouse inflammatory models. L-156602 suppresses the efferent phase of delayed-type hypersensitivity (DTH) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
