135 Results for "

Neurite

" in MedChemExpress (MCE) Product Catalog:
Products (135)

135 Results for "Neurite" in MCE Product Catalog:

Cat. No.: HY-113357R
CAS No.: 588-30-7
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats .
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Cat. No.: HY-148750
CAS No.: 1627834-10-9
Synonyms: BD10-2
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

PTX-BD10-2 (BD10-2) is an orally active TrkB/C modulator. PTX-BD10-2 ameliorates BFCN degeneration. PTX-BD10-2 restores cholinergic neurite integrity, alleviates cholinergic neurite atrophy. PTX-BD10-2 can be used in the research of Alzheimer's disease .
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Cat. No.: HY-N9085
CAS No.: 180964-26-5
Target:  

Bacterial

Neuchromenin is a microbial melabolite that can be isolated from the culture broth of Eupenicillium javanicum var. meloforme PFll81. Neuchromenin induces neurite outgrowth of PC12 cells .
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Cat. No.: HY-N3928
CAS No.: 173294-74-1
Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases .
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Cat. No.: HY-N15711
CAS No.: 2230922-02-6
Ganoleucoin R is a triterpenoid compound that can be isolated from Ganoderma leucocontextum. Ganoleucoin R exerts a protective effect against H2O2-induced oxidative damage and can promote neurite outgrowth in PC12 cells. Ganoleucoin R possesses neuroprotective and neurogenic activities, and can be used in the research of neurodegenerative diseases .
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Cat. No.: HY-165616
CAS No.: 309711-72-6
Target:  

Trk Receptor

Research Areas:  

Neurological Disease

NS 1231 is a neurotrophic-like compound with neuroprotective effect. NS 1231 can rescue nerve growth factor (NGF)-differentiated PC12 cells from death induced by withdrawal of trophic factors. NS 1231 can stimulate NGF-induced neurite outgrowth of undifferentiated PC12 cells. NS 1231 can be used for the research of neurological disease, such as stroke .
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Cat. No.: HY-11055
CAS No.: 393856-87-6
Research Areas:  

Neurological Disease

KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective .
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Cat. No.: HY-131931A
Synonyms: LysoGM1 ammonium
Target:  

Src

Research Areas:  

Neurological Disease

Lysoganglioside-GM1 (LysoGM1) ammonium is a derivative of Monosialoganglioside GM1, which lacks a fatty acid. Lysoganglioside-GM1 ammonium is also an inhibitor of GM1 aggregation. Lysoganglioside-GM1 ammonium can inhibit the activation of Lyn and laminin-1-mediated neurite outgrowth. Lysoganglioside-GM1 ammonium can be used in the research of nervous system diseases .
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Cat. No.: HY-147681
CAS No.: 1080650-67-4
Target:  

FGFR

Research Areas:  

Neurological Disease

SUN13837 is an orally active, blood-brain barrier permeable FGFR modulator and neuroprotective agent. SUN13837 mimics the activity of basic fibroblast growth factor, stimulates intracellular tyrosine phosphorylation of FGFR and signal transduction in neuronal cells, induces neurite outgrowth, and inhibits glutamate-induced neuronal death. SUN13837 can be used in research related to acute cervical spinal cord injury and severe spinal cord injury .
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Cat. No.: HY-146678
CAS No.: 2413603-15-1
Research Areas:  

Neurological Disease

HDAC6-IN-5 (compound 11b) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC50 of 0.025 μM. HDAC6-IN-5 exhibits strong inhibitory activity against Aβ1-42 self-aggregation and AChE, with IC50 values of 3.0 and 0.72 μM. HDAC6-IN-5 can enhance neurite outgrowth without significant neurotoxicity .
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Cat. No.: HY-146679
CAS No.: 2413603-10-6
Research Areas:  

Neurological Disease

HDAC6-IN-6 (compound 6a) is a potent and BBB-penetrated HDAC6 inhibitor, with an IC50 of 0.025 μM. HDAC6-IN-6 exhibits strong inhibitory activity against Aβ1-42 self-aggregation and AChE, with IC50 values of 3.0 and 0.72 μM. HDAC6-IN-6 can enhance neurite outgrowth without significant neurotoxicity .
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Cat. No.: HY-P5754
Target:  

Apoptosis

Research Areas:  

Neurological Disease

TAT-NEP1-40 is a BBB-penatrable peptide. TAT-NEP1-40 protects PC12 cells against oxygen and glucose deprivation (OGD), and promotes neurite outgrowth. TAT-NEP1-40 also improves ischemia-induced neurologic outcomes by inhibiting cell apoptosis in ischemic brains. TAT-NEP1-40 can be used for research of CNS injuries, such as axonal regeneration and functional recovery after stroke .
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Cat. No.: HY-158131
CAS No.: 601511-07-3
Target:  

FKBP HSP

Research Areas:  

Neurological Disease Cancer

FKBP51-Hsp90-IN-2 (Compound E08) is a selective FKBP51-Hsp90 protein-protein interaction inhibitor with IC50 values of 0.4 µM and 5 µM for FKBP51 and FKBP52, respectively. FKBP51-Hsp90-IN-2 also effectively stimulates cellular energy metabolism and neurite growth. FKBP51-Hsp90-IN-2 can be used in research on neurodegenerative diseases and cancer .
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Cat. No.: HY-N10325
CAS No.: 1367624-30-3
Scabronine M is a novel inhibitor of NGF-induced neurite outgrowth from PC12 cells.
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Cat. No.: HY-N14417
CAS No.: 253450-08-7
Target:  

Others

Indocarbazostatin against Neurite outgrowth induced by NGF is 6 nM in rat pheochromocytoma PC12 cells .
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Cat. No.: HY-N14424
CAS No.: 334831-87-7
Target:  

Others

Indocarbazostatin B against Neurite outgrowth induced by NGF is 24 nM in rat pheochromocytoma PC12 cells .
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Cat. No.: HY-149500
CAS No.: 2379989-52-1
Target:  

Estrogen Receptor/ERR

Research Areas:  

Metabolic Disease

CITFA is a GPER agonist. CITFA can promote neurite growth of hippocampal neurons in rat embryo (E18) .
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Cat. No.: HY-N3482
CAS No.: 659747-28-1
Isogarciniaxanthone E (compound 1) is a natural product that can be found in Garcinia xanthochymus. Isogarciniaxanthone E enhances nerve growth factor-mediated neurite outgrowth .
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Cat. No.: HY-116202
CAS No.: 1431724-30-9
PACA is an enhancer of nerve growth factor-induced neurite outgrowth, enhancing nerve growth factor (NGF)-induced neurite outgrowth and attenuating 6-hydroxydopamine (6-OHDA)-induced toxicity by activating the Nrf2/HO-1 pathway. PACA has neuroprotective and neurogenic activities. PACA can be used to improve dopaminergic neuron loss and motor dysfunction in MPTP mouse models of Parkinson's disease and MPP +-induced neurons .
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Cat. No.: HY-100460
CAS No.: 1070424-33-7
Target:  

ROCK

Research Areas:  

Cancer

BIPM is a potent ROCK2 inhibitor. BIPM leads to significant changes in neurite length, cell migration and actin stress fibers. BIPM plays an important role in anti-cancer metastasis .
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