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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
195 Results for "
ror+
" in MedChemExpress (MCE) Product Catalog:
Products (195)
195 Results for "ror+" in MCE Product Catalog:
Cat. No.: HY-170996
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ROR1 ligand-1 is a ROR1 ligand that can be used for synthesis of PROTACT ROR1 degrader-1 (HY-170995) .
Cat. No.: HY-RS12124
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ROR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12125
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ROR2 Human Pre-designed siRNA Set A contains three designed siRNAs for ROR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16801
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Ror1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ror1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-128353
CAS No.: 2361528-74-5
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ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5 .
Cat. No.: HY-170370
CAS No.: 2247604-77-7
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RORγt inverse agonist 34 (compound 5a) is a RORγt inverse agonist with an IC50 of 0.094 μM for RORγt-LBD. RORγt inverse agonist 34 is used for psoriasis research .
Cat. No.: HY-126321
CAS No.: 2377378-89-5
RORγt agonist 1 (compound 14) is a potent, orally bioavailable RORγt agonist with an EC50 of 20.8 nM. RORγt agonist 1 showes high metabolic stability, improved aqueous solubility and excellent mouse PK profile. RORγt agonist 1 is a potential candidate of RORγt agonist for cancer immunotherapy .
Cat. No.: HY-122737
CAS No.: 2079892-79-6
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RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist, with an IC50 of 19 nM for human RORγt-LBD .
Cat. No.: HY-19510
CAS No.: 1426803-07-7
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RORγt inhibitor 4 (Compound 9a) is an orally active and a CNS-penetrating RORγt inhibitor. RORγt inhibitor 4 improves experimental autoimmune encephalomyelitis .
Cat. No.: HY-49076
CAS No.: 529500-72-9
RORγ inverse agonist 1 is the inverse agonist of RORγ .
Cat. No.: HY-147533
CAS No.: 1445901-41-6
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RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist with the IC50 of 46 nM. Targeting the nuclear receptor RORγt is effective in autoimmune disorders .
Cat. No.: HY-142296
CAS No.: 1561770-72-6
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RORγt inhibitor 1 is a RORγt allosteric inhibitor with an IC50 value of 1 nM.
Cat. No.: HY-160021
CAS No.: 2241769-59-3
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RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma .
Cat. No.: HY-132900
CAS No.: 2260631-91-0
RORγ agonist 1 is a potent and orally bioavailable RORγ agonist (EC50 = 21 nM) with antitumor activity.
Cat. No.: HY-142940
CAS No.: 2119042-65-6
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RORγt modulator 5 is a RORγt modulator with a Ki value of <100 nM. RORγt modulator 5 has the potential for inflammatory, metabolic, autoimmune and other diseases mediated by RORy study (WO2017132432A1; compound 2) .
Cat. No.: HY-142703
CAS No.: 2741870-21-1
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RORγt inverse agonist 28 is a potent reverse agonist of RORγt. RORγt inverse agonist 28 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 28 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 6) .
Cat. No.: HY-142806
CAS No.: 2738333-10-1
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RORγt inverse agonist 26 is a potent reverse agonist of RORγt. RORγt inverse agonist 26 regulates the differentiation of Th17 cells and inhibits the production of IL-17. RORγt inverse agonist 26 has the potential for the research of inflammation and autoimmune diseases (extracted from patent WO2021228215A1, compound 1) .
Cat. No.: HY-111748
CAS No.: 1801197-92-1
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RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM .
Cat. No.: HY-142939
CAS No.: 2188177-73-1
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RORγt modulator 4 is a RORγt modulator. RORγt modulator 4 has an activity to modulate IL-17A production in cells derived from mouse spleen (WO2018030550A1; compound 146) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
