321 Results for "

transient heating

" in MedChemExpress (MCE) Product Catalog:
Products (321)

321 Results for "transient heating" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-15620
CAS No.: 188247-01-0
Purity:  98.90%
Methylproamine is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks .
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1 Cited Publications
Cat. No.: HY-B0545R
CAS No.: 57-66-9
Probenecid (Standard) is the analytical standard of Probenecid. This product is intended for research and analytical applications. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.
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1 Cited Publications
Cat. No.: HY-121539
CAS No.: 70351-51-8
Purity:  98.35%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines .
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1 Cited Publications
Cat. No.: HY-101547
CAS No.: 901715-05-7
Purity:  99.71%
Target:  

TRP Channel

Research Areas:  

Cancer

TRPC6-IN-1 is a Transient Receptor Potential Canonical 6 Channel (TRPC6) inhibitor, with an EC50 of 4.66 μM.
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1 Cited Publications
Cat. No.: HY-K1103

MCE Coomassie Blue Fast Staining Solution (No Heating, 10×) uses Coomassie Brilliant Blue G250 as the dye. It can be used for rapid, sensitive staining of protein gels in SDS-PAGE or Native-PAGE without contamination, or for detecting residual proteins on PAGE gels after Western Blot transfer. The 25 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

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1 Cited Publications
Cat. No.: HY-P703329
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TRPM4; LTRPC4; transient receptor potential cation channel subfamily M member 4; hTRPM4; Calcium-activated non-selective cation channel 1; Long transient receptor potential channel 4; LTrpC-4; LTrpC4; Melastatin-4; LTrpC-4; PFHB1B; TRPM4B; EKVP6; FLJ20041
Species:  
Human
Source:  
HEK293
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1 Cited Publications
Cat. No.: HY-D0887
CAS No.: 4691-65-0
Synonyms: IMP disodium salt; Disodium inosinate
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .
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1 Cited Publications
Cat. No.: HY-P1651B
Target:  

TRP Channel

Research Areas:  

Cancer

SOR-C13 acetate is the acetate salt form of SOR-C13 (HY-P1651). SOR-C13 acetate is an antagonist for transient receptor potential vanilloid 6 (TRPV 6), with an IC50 of 14 nM. SOR-C13 acetate inhibits tumor growth in SKOV-3 xenograft mouse model .
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1 Cited Publications
Cat. No.: HY-110181
CAS No.: 883976-12-3
Purity:  99.89%
Target:  

TRP Channel

Research Areas:  

Metabolic Disease

M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
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1 Cited Publications
Cat. No.: HY-11062
CAS No.: 36945-98-9
Purity:  99.26%
Synonyms: AG-3-5
Target:  

TRP Channel

Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
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1 Cited Publications
Cat. No.: HY-114524
CAS No.: 103560-62-9
Purity:  ≥95.0%
Synonyms: 4-ONE
Target:  

TRP Channel

Research Areas:  

Cardiovascular Disease

(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist .
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1 Cited Publications
Cat. No.: HY-P99342
CAS No.: 2415933-40-1
Synonyms: REGN10987

Target:  

SARS-CoV

Research Areas:  

Infection

Imdevimab (REGN10987) is a human monoclonal antibody that targets SARS-CoV-2 virus. Imdevimab can be used in combination with Casirivimab (HY-P99341) to reduce viral load and transiently increases anti-receptor-binding domain IgG titers. Imdevimab maintains most of its neutralization activity against viruses with B.1.1.7, B.1.351 and mink cluster 5 spike proteins .
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1 Cited Publications
Cat. No.: HY-W011121
CAS No.: 3443-84-3
Synonyms: 2-OG
2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC50 value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) .
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1 Cited Publications
Cat. No.: HY-B1337S
CAS No.: 285979-70-6
Choline-d4 chloride is the d4-labeled Choline chloride (HY-B1337). Choline chloride is an orally active methylxanthine derivative. Choline chloride exhibits weak antihistaminic and anticholinergic activities and potentiates the effects of histamine and acetylcholine. Choline chloride relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates locomotor activity in the central nervous system, and induces transient hypotension following a pressor phase. Choline chloride modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline chloride is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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1 Cited Publications
Cat. No.: HY-B1173
CAS No.: 464-49-3
Synonyms: D-(+)-Camphor; (1R)-(+)-Camphor
(+)-Camphor (D-(+)-Camphor; (1R)-(+)-Camphor) is an isomer of Camphor. Camphor is an agonist of monoterpenoid transient receptor potential (TRP) channels (such as TRPV1, TRPV3, TRPM8) and an inhibitor of TRPA1 channels. Camphor's derivatives have multiple biological activities, including antibacterial, antiviral, antioxidant, analgesic and anticancer. Camphor can selectively activate cold-sensitive TRP channels and inhibit TRPA1-mediated nociceptive signals. Camphor stimulates the cold-sensing nerve endings in the skin and regulates the activity of ion channels to exert analgesic, anti-inflammatory and anti-itching effects. It also has anti-proliferative and anti-mutagenic activities on tumor cells, which may be related to inhibiting ribosome function or inducing cell apoptosis. Camphor can be absorbed through the skin and (+)-Camphor can be used in the study of muscle and joint pain and inflammation .
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Cat. No.: HY-128476
CAS No.: 868-18-8
Purity:  ≥99.0%
Research Areas:  

Others

Sodium Tartrate (E335ii) is an approved food additive that functions as both a pH regulator and an emulsifier. Sodium Tartrate effectively inhibits hydrolysis, thermal oxidation, polymerization and coloration of vegetable oil during high-temperature heating, exhibiting significant antioxidant activity. The DL-tartaric acid component of Sodium Tartrate has an absorption rate of up to 90% in brown rats, while the absorption rate of related tartaric acid in humans is only 20% .
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Cat. No.: HY-D0936
CAS No.: 83907-40-8
SPQ is a fluorescent dye. SPQ can be used to measure chloride ion concentration transients and transport rates in vesicles, cells, and even intact epithelium .
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Cat. No.: HY-101323
CAS No.: 58493-49-5
Purity:  ≥98.0%
Synonyms: NE-19550; N-Vanillyloleamide
Target:  

TRP Channel

Research Areas:  

Neurological Disease

Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC50 of 0.7 nM .
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Cat. No.: HY-108329
CAS No.: 1883711-97-4
Purity:  99.73%
Target:  

TRP Channel

AM-0902 is a potent, selective transient receptor potential A1 (TRPA1) antagonist with IC50s of 71 and 131 nM for rTRPA1 and hTRPA1, respectively.
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Cat. No.: HY-W017054
CAS No.: 115-69-5
Research Areas:  

Others

2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change material with energy release and heat storage properties. 2-Amino-2-methyl-1,3-propanediol can crystallize from a supercooled solid state, release thermal energy during heating, and store thermal energy in the supercooled solid state. 2-Amino-2-methyl-1,3-propanediol can be used in the production of surfactants, vulcanization accelerators, and as a biological buffer .
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