Supercinnamaldehyde
Based on 1 publication(s) in Google Scholar
Supercinnamaldehyde is a potent transient receptor potential ankyrin 1 (TRPA1) activator with an EC50 value of 0.8 μM. Supercinnamaldehyde activates TRPA1 ion channels through covalent modification of cysteines.
For research use only. We do not sell to patients.
- Purity: 98.75%
- CAS No.: 70351-51-8
- Formula: C12H11NO2
- Molecular Weight:201.22
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Supercinnamaldehyde
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Biological Activity
Chemical Information
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CAS No. 70351-51-8
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Appearance Solid
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Molecular Weight 201.22
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Formula C12H11NO2
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Color Brown to reddish brown
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SMILES
CN(C/1=O)C2=CC=CC=C2C1=C\C(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Headache
TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms. [Abstract]2025 Oct 24. PMID: 41133435
Solvent & Solubility
DMSO : 50 mg/mL (248.48 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9697 mL | 24.8484 mL | 49.6968 mL | 124.2421 mL |
| 5 mM | 0.9939 mL | 4.9697 mL | 9.9394 mL | 24.8484 mL | |
| 10 mM | 0.4970 mL | 2.4848 mL | 4.9697 mL | 12.4242 mL | |
| 15 mM | 0.3313 mL | 1.6566 mL | 3.3131 mL | 8.2828 mL | |
| 20 mM | 0.2485 mL | 1.2424 mL | 2.4848 mL | 6.2121 mL | |
| 25 mM | 0.1988 mL | 0.9939 mL | 1.9879 mL | 4.9697 mL | |
| 30 mM | 0.1657 mL | 0.8283 mL | 1.6566 mL | 4.1414 mL | |
| 40 mM | 0.1242 mL | 0.6212 mL | 1.2424 mL | 3.1061 mL | |
| 50 mM | 0.0994 mL | 0.4970 mL | 0.9939 mL | 2.4848 mL | |
| 60 mM | 0.0828 mL | 0.4141 mL | 0.8283 mL | 2.0707 mL | |
| 80 mM | 0.0621 mL | 0.3106 mL | 0.6212 mL | 1.5530 mL | |
| 100 mM | 0.0497 mL | 0.2485 mL | 0.4970 mL | 1.2424 mL |