![N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine](https://file.medchemexpress.com/product_pic/hy-154835.gif "Click to View N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
125 Results for "
integration
" in MedChemExpress (MCE) Product Catalog:
Products (125)
125 Results for "integration" in MCE Product Catalog:
Cat. No.: HY-164915
CAS No.: 1218932-97-8
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5-InoAz is an inositol analogue containing an azide group, which is used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
Cat. No.: HY-117879
CAS No.: 1515856-61-7
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PF-4776548 is a highly potent HIV integrase inhibitor. PF-477654 blocks the process of integrating HIV viral DNA into the host cell genome. PF-4776548 is promising for research of AIDS .
Cat. No.: HY-172333
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HCy-Lyso is a lysosome-targeting turn-on fluorescent probe based on hydrocyanine. HCy-Lyso integrates a hydrocyanine moiety for selective recognition of hydroxyl radicals (•OH) and a morpholine group for lysosome targeting. Upon reacting with •OH, HCy-Lyso undergoes an extension of its π-conjugation system, producing a strong fluorescence signal at 598 nm when excited at 510 nm .
Cat. No.: HY-178741
KFA-027 is a HIV-1 inhibitor, with an IC50 of 0.398 nM. KFA-027 inhibits capsid-dependent early steps (reverse transcription, nuclear import, integration) and late-stage aberrant capsid assembly in the HIV-1 replication cycle. KFA-027 can be used for the study of multidrug-resistant HIV-1 infections .
Cat. No.: HY-121348
CAS No.: 59458-27-4
Synonyms: U-47929
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Cat. No.: HY-113218S
CAS No.: 203805-90-7
Synonyms: O-Acetyl-L-carnitine-d9; ALCAR-d9
Cat. No.: HY-147653
CAS No.: 1431738-14-5
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Integrase-LEDGF/p75 allosteric inhibitor 1 (Compound 31h) is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. Integrase-LEDGF/p75 allosteric inhibitor 1 inhibits HIV-1 DNA integration and shows antiviral activity with an EC50 of 3.9 nM against HIV-1 recombinant molecular clone NL432 .
Cat. No.: HY-106634R
CAS No.: 459-86-9
Synonyms: Methylglyoxal-bis(guanylhydrazone) (Standard); MGBG (Standard); Methyl-GAG (Standard)
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Mitoguazone (Standard) is the analytical standard of Mitoguazone. This product is intended for research and analytical applications. Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
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Thioacetanilide (N-Phenylthioacetamide) is a sulfur-containing thioamide derivative of acetanilide. Thioacetanilide displays a solvent‑dependent Z/E isomeric distribution, preferring the E conformation in polar hydrogen‑bonding solvents and the Z conformation in halogenated solvents. Thioacetanilide serves as a substrate for metabolic desulfurization and aromatic hydroxylation. Thioacetanilide is mainly metabolized via desulfurization and 4‑hydroxylation of the aromatic ring in Rattus norvegicus, and the released sulfur integrates into the total body sulfur pool. Thioacetanilide is well absorbed in rats, and more than 90% of the dose is excreted in urine as conjugated metabolites after oral administration .
Cat. No.: HY-134180
CAS No.: 144490-73-3
rel-Carbovir monophosphate is the -enantiomer of 2',3'-dideoxy-2',3'-didehydroguanosine and a carbocyclic analog of carbovir (CBV). Carbovir is an inhibitor of HIV replication that specifically inhibits the integration of proribonucleotides into DNA .
β-catenin-IN-6 is a β-catenin inhibitor, targeting to canonical Wingless-related integration site signaling pathway. β-catenin-IN-6 inhibits human colorectal cancer cells proliferation, as well as in a β-catenin/RK3E mouse model .
Cat. No.: HY-B0359R
CAS No.: 73151-29-8
Synonyms: REC 15-1476 (Standard)
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Fenticonazole (Nitrate) (Standard) is the analytical standard of Fenticonazole (Nitrate). This product is intended for research and analytical applications. Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
Cat. No.: HY-122256
CAS No.: 410545-90-3
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L-870812 is a HIV-1 integration with integrase strand transfer inhibitor. L-870812 consistently blocks cell-free and cell-associated HIV-1 infection. L-870812 blocks subtype C and CRFO2_AG primary isolates. L-870812 can be used for the study of replication-deficient HIV-1 Ba-L (env) pseudovirus .
Cat. No.: HY-154835
CAS No.: 1513855-74-7
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N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine is an unnatural lysine analog and a substrate of the PABKRS mutant PylRS. N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine enables site-specific genetic integration into proteins via amber stop codon suppression; it undergoes Staudinger reduction with phosphine compounds, followed by a self-elimination reaction to release native lysine. N6-[[(4-Azidophenyl)methoxy]carbonyl]-L-lysine serves as a genetically encoded element for the temporal chemical control of protein SUMOylation and nuclear translocation in living mammalian cells, and also acts as a bioorthogonal reaction handle for bioconjugation reactions .
Cat. No.: HY-178988
Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC₅₀ value of 6.9 μg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC₅₀ = 32.5 ± 3.0 μg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
