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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
101 Results for "
pc12
" in MedChemExpress (MCE) Product Catalog:
Products (101)
101 Results for "pc12" in MCE Product Catalog:
Cat. No.: HY-161783
CAS No.: 3048532-05-1
Research Areas:
HDAC6-IN-45 (Compound 15) is a selective inhibitor for HDAC6 with IC50 of 15.2 nM. HDAC6-IN-45 exhibits neurotrophic through the upregulation of GAP43 and Beta-3 tubulin markers. HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, inhibits apoptosis in PC12, and exhibits neuroprotective efficacy in SCOP-induced zebrafish Alzheimer's Disease models. HDAC6-IN-45 exhibits antioxidant activity and good blood-brain barrier (BBB) permeability .
Cat. No.: HY-P11313
Synonyms: Rat chromogranin A367–387
Research Areas:
Cat. No.: HY-N10325
CAS No.: 1367624-30-3
Target:
Cat. No.: HY-N14417
CAS No.: 253450-08-7
Category:
Target:
Cat. No.: HY-N14424
CAS No.: 334831-87-7
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Cat. No.: HY-N8103
CAS No.: 1469493-85-3
Category:
Valerianaceae Extract Terpenoids Sesquiterpenes Plants Valeriana amurensis Smir. ex Komarov
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Cat. No.: HY-161502
Target:
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DHX-SP is a fluorescent probe, which visualizes superoxide anion (O2 ·–) and peroxynitrite (ONOO –) during ferroptosis of PC12 cells and in the Parkinson’s disease model .
Cat. No.: HY-N3563
CAS No.: 244204-40-8
Category:
Celastraceae Extract Terpenoids Celastrus Diterpenoids Plants Celastrus orbiculatus Thunb.
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Cat. No.: HY-N12001
CAS No.: 2580359-99-3
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Target:
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Chrysamine G, a carboxylic acid analogue of Congo Red, can be used as a probe of amyloid deposition in Alzheimer's disease. Chrysamine G also can inhibit Aβ-induced toxicity in PC12 cells .
Cat. No.: HY-N12225
CAS No.: 948827-09-6
Category:
Triterpenes Umbelliferae Extract Terpenoids Centella asiatica (L.) Urb. Plants Pentacyclic Triterpenoids
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Cat. No.: HY-162330
Target:
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HDAC6-IN-36 (compound 11d) is an inhibitor of HDAC6 with IC50 value of 8.64 nM. HDAC6-IN-36 induces neurite outgrowth of PC12 cells without producing toxic effects.
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AnnH31 is a Dyrk1A inhibitor (IC50: 81 nM). AnnH31 also inhibits MAO-A with an IC50 of 3.2 μM. AnnH31 inhibits cell viability of HeLa, PC12 and SH-SY5Y cells .
Cat. No.: HY-155049
Target:
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NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis .
Cat. No.: HY-W339358
CAS No.: 27869-47-2
Synonyms: 1,2-Diundecanoyl-sn-glycero-3-phosphocholine
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11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which plays a role in the folding of intact, functionally competent integral membrane proteins .
Cat. No.: HY-N3928
CAS No.: 173294-74-1
Category:
Flavonoids Garcinia xanthochymus Hook. f. ex T. Anders. Guttiferae Extract Flavonones Plants
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Cat. No.: HY-N9257
CAS No.: 112747-99-6
Category:
Valerianaceae Extract Lignans Phenylpropanoids Plants Valeriana amurensis Smir. ex Komarov
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Cat. No.: HY-168068
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Res-Glu3 is the derivative of Resveratrol (HY-16561). Res-Glu3 mitigates the ROS accumulation, and exhibits neuroprotective efficacy against H2O2-caused cellular damage in PC12. Res-Glu3 exhibits antioxidant activity in rats ischemia reperfusion models .
Cat. No.: HY-N12123
CAS No.: 1407161-78-7
Category:
Alkaloids Other Alkaloids Plants Fritillaria unibracteata Hsiao et K. C. Hsia Liliaceae Extract
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Cat. No.: HY-G0008AR
CAS No.: 856620-39-8
Synonyms: Mebeverine metabolite O-desmethyl Mebeverine alcohol hydrochloride (Standard)
Research Areas:
Diethyl phthalate (Standard) is the analytical standard of Diethyl phthalate. This product is intended for research and analytical applications. Diethyl phthalate is an endocrine disruptor that has the activity of affecting the apoptosis system of PC12 cells. Diethyl phthalate is widely used in a variety of plastics and personal care products. Diethyl phthalate has shown the potential to induce male reproductive toxicity unrelated to androgens in animal experiments .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
