1119 Results for "

toad bladder preparations

" in MedChemExpress (MCE) Product Catalog:
Products (1119)

1119 Results for "toad bladder preparations" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-152229
CAS No.: 1510653-27-6
Purity:  ≥98.0%
Target:  

Liposome

Research Areas:  

Cancer

G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
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2
2 Cited Publications
Cat. No.: HY-145722A
CAS No.: 1002331-21-6
Synonyms: OGX-427
Target:  

HSP

Research Areas:  

Cancer

Apatorsen is a 2'-methoxyethyl-modified antisense oligonucleotide and also a Hsp27 inhibitor. Apatorsen reduces Hsp27 mRNA and protein levels, impairs stress-induced cytoprotective functions, induces cell apoptosis, inhibits tumor growth and prevents metastasis. Apatorsen is applicable to research related to non-small cell lung cancer, castration-resistant prostate cancer, breast cancer, ovarian cancer and bladder cancer .
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2
2 Cited Publications
Cat. No.: HY-145722
CAS No.: 915443-09-3
Purity:  98.54%
Synonyms: OGX-427 sodium
Target:  

HSP

Research Areas:  

Cancer

Apatorsen (OGX-427) sodium is a 2'-methoxyethyl-modified antisense oligonucleotide and also a Hsp27 inhibitor. Apatorsen sodium reduces Hsp27 mRNA and protein levels, impairs stress-induced cytoprotective functions, induces cell apoptosis, inhibits tumor growth and prevents metastasis. Apatorsen sodium is applicable to research related to non-small cell lung cancer, castration-resistant prostate cancer, breast cancer, ovarian cancer and bladder cancer .
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2
2 Cited Publications
Cat. No.: HY-P0004
CAS No.: 50-57-7
Synonyms: Lysine vasopressin; [Lys8]-Vasopressin
Lysipressin (Lysine vasopressin ; [Lys8]-Vasopressin ) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin depends on the sympathetic tone pathway. Lysipressin dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin can be used in studies related to cardiovascular regulation, hypertension and pain .
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2
2 Cited Publications
Cat. No.: HY-P0004A
CAS No.: 83968-49-4
Synonyms: Lysine vasopressin acetate; [Lys8]-Vasopressin acetate
Lysipressin acetate (Lysine vasopressin acetate; [Lys8]-Vasopressin acetate) is a neurohypophyseal nonapeptide with dual cardiovascular regulatory activities of peripheral pressor action and central hypotensive action, and it also regulates pain perception in the body. Lysipressin acetate is an Oxytocin Receptor agonist, with a Ki value of 10.2 nM for porcine OT receptor. Lysipressin acetate stimulates contraction of rabbit bladder smooth muscle via V1-vasopressin receptor. The central hypotensive effect of Lysipressin acetate depends on the sympathetic tone pathway. Lysipressin acetate dose-dependently prolongs tail-flick latency in rats, producing a stable central antinociceptive effect. Lysipressin acetate can be used in studies related to cardiovascular regulation, hypertension and pain .
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2
2 Cited Publications
Cat. No.: HY-162318
CAS No.: 2946670-96-6
Research Areas:  

Cancer

MYC degrader 1 is a MYC degrader that recruits Cereblon (CRBN), with a Kd value of 145 nM and oral activity. MYC degrader 1 specifically binds MYC and GSPT1, recruits the CRBN E3 ubiquitin ligase complex, and induces MYC degradation via the ubiquitin-proteasome pathway. MYC degrader 1 downregulates KLHL42 expression, restores pRB1 protein levels, and re-establishes the sensitivity of MYC-overexpressing cancer cells to CDK4/6 inhibitors. MYC degrader 1 combined with Palbociclib (HY-50767) shows significant inhibition of tumor growth. MYC degrader 1 can be used in studies related to bladder cancer, prostate cancer, and breast cancer .
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2
2 Cited Publications
Cat. No.: HY-162318A
Target:  

c-Myc

Research Areas:  

Cancer

MYC degrader 1 TFA is a MYC degrader that recruits Cereblon (CRBN), with a Kd value of 145 nM and oral activity. MYC degrader 1 TFA specifically binds MYC and GSPT1, recruits the CRBN E3 ubiquitin ligase complex, and induces MYC degradation via the ubiquitin-proteasome pathway. MYC degrader 1 TFA downregulates KLHL42 expression, restores pRB1 protein levels, and re-establishes the sensitivity of MYC-overexpressing cancer cells to CDK4/6 inhibitors. MYC degrader 1 TFA combined with Palbociclib (HY-50767) shows significant inhibition of tumor growth. MYC degrader 1 TFA can be used in studies related to bladder cancer, prostate cancer, and breast cancer .
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2
2 Cited Publications
Cat. No.: HY-W014589
CAS No.: 96-76-4
Synonyms: 2,4-DTBP
2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances .
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1
1 Cited Publications
Cat. No.: HY-Y0406H
CAS No.: 10043-52-4
Synonyms: Calcium dichloride anhydrous, powder, 97%
Calcium chloride anhydrous, powder, 97% is an inorganic salt for the preparation of various buffers .
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1
1 Cited Publications
Cat. No.: HY-P1494
CAS No.: 57468-17-4
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
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1
1 Cited Publications
Cat. No.: HY-W142395
CAS No.: 150322-06-8
6-TAMRA free acid is a fluorophore widely used in the preparation of fluorescent antibodies and avidin derivatives for immunohistochemistry.
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1
1 Cited Publications
Cat. No.: HY-N2384
CAS No.: 24159-07-7
Febrifugine is a quinazolinone alkaloid that inhibits P. falciparum and has antimalarial activity. Febrifugine inhibits bladder cancer by inhibiting DNA synthesis, inducing apoptosis, and reducing steroids .
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1
1 Cited Publications
Cat. No.: HY-N2384A
CAS No.: 32434-42-7
Febrifugine dihydrochloride is a quinazolinone alkaloid that inhibits P. falciparum and has antimalarial activity. Febrifugine dihydrochloride inhibits bladder cancer by inhibiting DNA synthesis, inducing apoptosis, and reducing steroids .
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1
1 Cited Publications
Cat. No.: HY-154631
CAS No.: 8002-03-7
Purity:  99.2%
Research Areas:  

Others

Peanut Oil can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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1
1 Cited Publications
Cat. No.: HY-Y0873E
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 1500
PEG1500 can be used as an excipient, such as ointment base, lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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1
1 Cited Publications
Cat. No.: HY-108719
CAS No.: 160337-95-1
Insulin glargine is a long-acting insulin analog. Insulin glargine has the effect of lowering blood sugar and can be used in the research of diabetes. In addition, high doses of Insulin glargine can promote the proliferation of bladder cancer cells .
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1
1 Cited Publications
Cat. No.: HY-B2068
CAS No.: 8047-67-4
Synonyms: Iron saccharate
Research Areas:  

Metabolic Disease Cancer

Iron sucrose (Iron saccharate) is a intravenous iron preparation and a pro-oxidant agent. Iron sucrose has the potential for iron deficiency anemia treatment .
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1
1 Cited Publications
Cat. No.: HY-153728
CAS No.: 2894832-05-2
Purity:  98.74%
Target:  

WDR5

Research Areas:  

Cancer

WM-586 is a covalent WDR5 inhibitor. WM-586 specifically decreases WDR5 and MYC interaction with an IC50 of 101 nM. WM-586 is used in research on a variety of cancers including neuroblastoma, breast cancer, bladder cancer and colorectal cancer .
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1
1 Cited Publications
Cat. No.: HY-114244
CAS No.: 1373268-67-7
Purity:  99.82%
Target:  

CXCR

Research Areas:  

Cancer

USL311 is an orally active CXCR4 inhibitor. USL311 blocks the activity of the CXCR4 receptor. USL311 is applicable to research related to various cancers including breast cancer, bladder cancer, colon cancer, rectal cancer, liver cancer and glioblastoma .
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1
1 Cited Publications
Cat. No.: HY-19933
CAS No.: 1190389-15-1
Synonyms: MK-4618
Target:  

Adrenergic Receptor

Research Areas:  

Others

Vibegron (MK-4618) is a potent, highly selective and orally active β3-adrenoceptor agonist (EC50=1.1 nM). Vibegron can be used for severe urgency urinary incontinence related to overactive bladder .
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