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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
171 Results for "
ErbB2
" in MedChemExpress (MCE) Product Catalog:
Products (171)
171 Results for "ErbB2" in MCE Product Catalog:
Cat. No.: HY-P990695
CAS No.: 2642197-17-7
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Cat. No.: HY-P990972
CAS No.: 2920336-42-9
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Cat. No.: HY-103443A
CAS No.: 915942-25-5
HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 dimaleate suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation .
Cat. No.: HY-W008914
CAS No.: 537705-08-1
(E/Z)-CP-724714 is a racemic compound of (E)-CP-724714 and (Z)-CP-724714 isomers. CP-724714 is a potent and selective orally active ErbB2 (HER2) inhibitor .
Cat. No.: HY-13272S2
Synonyms: PF-00299804-d10 dihydrochloride; PF-299804-d10 dihydrochloride
Cat. No.: HY-13272S3
Synonyms: PF-00299804-d10; PF-299804-d10
Cat. No.: HY-174671
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Human HBEGF mRNA encodes the human heparin binding EGF like growth factor (HBEGF) protein, a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. HBEGF may be involved in normal cardiac valve formation and normal heart function.
Cat. No.: HY-P990596
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Cat. No.: HY-32718R
CAS No.: 257933-82-7
Synonyms: EKB-569 (Standard); WAY-EKB 569 (Standard)
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Pelitinib (Standard) is the analytical standard of Pelitinib. This product is intended for research and analytical applications. Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC50 of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282, 800, and 1255 nM, respectively.
Cat. No.: HY-32718S
CAS No.: 1325223-34-4
Cat. No.: HY-10367AR
CAS No.: 289499-45-2
Synonyms: CI-1033 dihydrochloride (Standard); PD-183805 dihydrochloride (Standard)
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Canertinib (dihydrochloride) (Standard) is the analytical standard of Canertinib (dihydrochloride). This product is intended for research and analytical applications. Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice [2] .
Cat. No.: HY-10367R
CAS No.: 267243-28-7
Synonyms: CI-1033 (Standard); PD-183805 (Standard)
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Canertinib (Standard) is the analytical standard of Canertinib. This product is intended for research and analytical applications. Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice [2] .
Cat. No.: HY-123726
CAS No.: 231277-83-1
ErbB-1/ErbB-2 tyrosine kinase-IN-1 is a dual ErbB-1/ErbB-2 tyrosine kinase inhibitor with IC50 values of 0.027 μM and 0.026 μM. ErbB-1/ErbB-2 tyrosine kinase-IN-1 targets the ATP binding region of ErbB-1 and ErbB-2 tyrosine kinases. ErbB-1/ErbB-2 tyrosine kinase-IN-1 inhibits cancer cells proliferation .
Cat. No.: HY-P991979
Cat. No.: HY-103440R
CAS No.: 881001-19-0
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EGFR/ErbB-2/ErbB-4 inhibitor-3 (Standard) is the analytical standard of EGFR/ErbB-2/ErbB-4 inhibitor-3 (HY-103440). This product is intended for research and analytical applications. EGFR/ErbB-2/ErbB-4 inhibitor-3 (compound 29) is a potent tyrosine kinase inhibitor with IC50s of 0.3, 1.1, 0.5, 2.5, 24 nM for erbB1, erbB2, erbB4, EGF, HER, respectively . EGFR/ErbB-2/ErbB-4 inhibitor-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-50898S5
CAS No.: 1210608-87-9
Synonyms: GW572016-13C,d7; GW2016-13C,d7
Cat. No.: HY-103439A
CAS No.: 388082-81-3
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GW583340 is an orally active ErbB-2/EGFR tyrosine kinase inhibitor. GW583340 exhibits antitumor activity in xenograft models with EGFR overexpression or ErbB-2 overexpression. GW583340 is applicable to research related to head and neck cancer, breast cancer, and gastric cancer .
Cat. No.: HY-P992107
CAS No.: 3058433-18-1
Cat. No.: HY-P83761
Synonyms: ErbB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340
Cat. No.: HY-10045R
CAS No.: 497839-62-0
Synonyms: NVP-AEE 788 (Standard)
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AEE788 (Standard) is the analytical standard of AEE788 (HY-10045). This product is intended for research and analytical applications. AEE788 is an inhibitor of the EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
