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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
171 Results for "
ErbB2
" in MedChemExpress (MCE) Product Catalog:
Products (171)
171 Results for "ErbB2" in MCE Product Catalog:
Cat. No.: HY-P991524
CAS No.: 1361108-53-3
Cat. No.: HY-P99558
CAS No.: 1665274-14-5
Synonyms: GEXMab73; GT-MAb7.3-GEX; TrastuzuMab-GEX
Cat. No.: HY-103439
CAS No.: 1173023-85-2
Target:
Research Areas:
GW 583340 dihydrochloride is an orally active ErbB-2/EGFR tyrosine kinase inhibitor. GW 583340 dihydrochloride exhibits antitumor activity in xenograft models with EGFR overexpression or ErbB-2 overexpression. GW 583340 dihydrochloride is applicable to research related to head and neck cancer, breast cancer, and gastric cancer .
Cat. No.: HY-P990909
CAS No.: 2254097-05-5
Synonyms: XMT-1519; XMT-1522 antibody
Target:
Research Areas:
Cat. No.: HY-P990978
CAS No.: 2930815-95-3
Synonyms: FS-1502 Antibody; IKS-014 Antibody
Target:
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Cat. No.: HY-13272R
CAS No.: 1110813-31-4
Synonyms: PF-00299804 (Standard); PF-299804 (Standard)
Target:
Research Areas:
Dacomitinib (Standard) is the analytical standard of Dacomitinib. This product is intended for research and analytical applications. Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively .
Cat. No.: HY-156639
CAS No.: 1135150-79-6
EGFR/ErbB-2 inhibitor-1 is a ErbB2/HER2 inhibitor .
Cat. No.: HY-50898C
CAS No.: 1187538-35-7
Synonyms: GW572016 tosylate; GW2016 tosylate
Target:
Research Areas:
Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-137028
CAS No.: 136904-69-3
Synonyms: PD157432
2'-Thioadenosine (PD157432) is a selective and irreversible inhibitor of ErbB-1 and ErbB-2, with an IC50 of 45 µM for ErbB-2. 2'-Thioadenosine covalently inactivates ErbB-1 via modification of a cysteine residue at the active site .
Cat. No.: HY-50898S2
CAS No.: 2748212-14-6
Synonyms: GW572016-d5; GW2016-d5
Cat. No.: HY-50898S3
CAS No.: 1184264-15-0
Synonyms: GW572016-d4-1; GW2016-d4-1
Cat. No.: HY-50898R
CAS No.: 231277-92-2
Synonyms: GW572016 (Standard); GW2016 (Standard)
Target:
Research Areas:
Lapatinib (Standard) is the analytical standard of Lapatinib. This product is intended for research and analytical applications. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898BR
CAS No.: 388082-78-8
Synonyms: GW572016 ditosylate monohydrate (Standard); GW2016 ditosylate monohydrate (Standard)
Target:
Research Areas:
Lapatinib (ditosylate monohydrate) (Standard) is the analytical standard of Lapatinib (ditosylate monohydrate). This product is intended for research and analytical applications. Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898AR
CAS No.: 388082-77-7
Synonyms: GW572016 ditosylate (Standard); GW2016 ditosylate (Standard)
Target:
Research Areas:
Lapatinib (ditosylate) (Standard) is the analytical standard of Lapatinib (ditosylate). This product is intended for research and analytical applications. Lapatinib ditosylate (GW572016 ditosylate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively .
Cat. No.: HY-50898CS
CAS No.: 2749856-05-9
Synonyms: GW572016-d4 tosylate; GW2016-d4 tosylate
Research Areas:
Lapatinib-d4 (GW572016-d4) tosylate is deuterium labeled Lapatinib (tosylate). Lapatinib (GW572016) tosylate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively [2].
Cat. No.: HY-W777297
CAS No.: 1246819-08-8
Cat. No.: HY-129288
CAS No.: 833473-68-0
Synonyms: NEU-391
Target:
Research Areas:
GW837016X (NEU-391) is an orally active ErbB-2 kinase covalent inhibitor. GW837016X also is a potent antitrypanosome agent. GW837016X inhibits mitosis and cytokinesis .
Cat. No.: HY-13050A
CAS No.: 1196531-39-1
Synonyms: AZD-8931 fumarate
Sapitinib fumarate is a reversible, ATP competitive EGFR inhibitor of with IC50s of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3 in cells, respectively.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
