272 Results for "

intake

" in MedChemExpress (MCE) Product Catalog:
Products (272)

272 Results for "intake" in MCE Product Catalog:

Referencia número: HY-19848
No. CAS: 839673-52-8
Synonyms: LBM-642
Target:  

PPAR

Áreas de investigación:  

Metabolic Disease

Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research .
loading...
    loading...
Referencia número: HY-P3561
Target:  

Melanocortin Receptor

Áreas de investigación:  

Neurological Disease

Agouti-related Protein (AGRP) (83-132) Amide (human) is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake .
loading...
    loading...
Referencia número: HY-149663
No. CAS: 1808258-99-2
Pureza:  99.48%
Target:  

Acyltransferase

Áreas de investigación:  

Metabolic Disease

BMS-986172 is an orally active and selective Monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 reduces food intake and body weight. BMS-986172 can be used for the researches of metabolic diseases, such as obesity .
loading...
    loading...
Referencia número: HY-P3130
No. CAS: 348626-74-4
Target:  

CRFR

Áreas de investigación:  

Neurological Disease Inflammation/Immunology

Stresscopin-related peptide (human) is a specific ligand for the type 2 CRH receptor. Stresscopin-related peptide (human) suppresses food intake, delayed gastric emptying and decreases heat-induced edema. Stresscopin-related peptide (human) maintains homeostasis after stress, and can be used in the research of stress-related diseases .
loading...
    loading...
Referencia número: HY-125088
No. CAS: 180003-17-2
Target:  

Apoptosis

Áreas de investigación:  

Metabolic Disease

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure .
loading...
    loading...
Referencia número: HY-P1421A
Target:  

GPR39

Áreas de investigación:  

Metabolic Disease

Obestatin(human) TFA is an endogenous peptide derived from the same prepropeptide as ghrelin. Obestatin(human) suppresses food intake and reduce body weight-gain in rats.
loading...
    loading...
Referencia número: HY-P11477
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Inflammation/Immunology

Nesfatin-1 (24-53), human is a fragment of human Nesfatin-1. Human Nesfatin-1 protein can rapidly inhibit food intake .
loading...
    loading...
Referencia número: HY-129207
No. CAS: 925239-03-8
Target:  

GHSR

Áreas de investigación:  

Endocrinology

Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that stimulates food intake and transduces signals to hypothalamic regulatory nuclei that control energy homeostasis. JMV3002 is a potent ghrelin receptor antagonist with an IC50 value of 1.1 nM in vitro. 80 μg/kg, JMV3002 inhibits hexarelin-stimulated food intake by as much as 98% in rats. JMV3002 alone does not elicit growth hormone release nor does it inhibit hexarelin-stimulated growth hormone secretion when tested in infant rats at a dose of 160 μg/kg.
loading...
    loading...
Referencia número: HY-W010042S1
No. CAS: 478519-05-0
Synonyms: L-(-)-Glucose-13C-1
L-Glucose- 13C-1 is the 13C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake .
loading...
    loading...
Referencia número: HY-107627
No. CAS: 475498-26-1
Pureza:  99.93%
Target:  

Melanocortin Receptor

Áreas de investigación:  

Inflammation/Immunology

MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake .
loading...
    loading...
Referencia número: HY-112612
No. CAS: 2244884-08-8
Target:  

GPR88

Áreas de investigación:  

Neurological Disease

RTI-13951-33 is a potent, selective, and brain-penetrant GPR88 agonist, with an EC50 of 25 nM in GPR88 cAMP functional assay. RTI-13951-33 reduces alcohol reinforcement and intake behaviors in rats .
loading...
    loading...
Referencia número: HY-147335
No. CAS: 845779-89-7
Target:  

Endogenous Metabolite

Áreas de investigación:  

Cardiovascular Disease

6,9,12,15-Hexadecatetraenoic acid-ethyl ester is an orally active n-1PUFA. 6,9,12,15-Hexadecatetraenoic acid-ethyl ester intake can reduce plasma triglyceride content in mice .
loading...
    loading...
Referencia número: HY-P4815
No. CAS: 423206-00-2
Target:  

Endogenous Metabolite

Áreas de investigación:  

Neurological Disease Metabolic Disease

Prokineticin 2 Isoform 2 (human) is a hypothalamic neuropeptide. Prokineticin 2 Isoform 2 (human) decreases food intake and involves in thermoregulation and energy metabolism in rodents. Prokineticin 2 has the potential for the research of hyperglycemia, metabolic syndrome (MetS) and obesity .
loading...
    loading...
Referencia número: HY-W101609
No. CAS: 140-26-1
Phenylethyl isovalerate is a synthetic flavoring substance with very low acute oral toxicity. Phenylethyl isovalerate after long-term low-dose intake increases the activity of alanine aminotransferase (ALT) and the level of sulfhydryl groups in the serum, but decreases the activity of cholinesterase (ChE) .
loading...
    loading...
Referencia número: HY-111583
No. CAS: 2351104-40-8
Target:  

RXFP Receptor

Áreas de investigación:  

Metabolic Disease

RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats .
loading...
    loading...
Referencia número: HY-P2046
No. CAS: 309246-19-3
Target:  

Opioid Receptor

Áreas de investigación:  

Neurological Disease

β-Endorphin (rat) is an endogenous opioid neuropeptide and peptide hormone. β-Endorphin (rat) has analgesic activity and also contributes to food intake in satiated rats. β-Endorphin (rat) can be used in the research of neurological diseases such as analgesia and drug addiction .
loading...
    loading...
Referencia número: HY-117158
No. CAS: 81998-18-7
Target:  

Adrenergic Receptor

Áreas de investigación:  

Others

SKF 89748 is an α1-adrenergic receptor agonist with the activity of inhibiting food and water intake. SKF 89748 inhibits food and water intake in adult male rats with an ED50 of 0.37mg/kg for inhibiting food intake.
loading...
    loading...
Referencia número: HY-114976
No. CAS: 23127-41-5
S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption .
loading...
    loading...
Referencia número: HY-122666
No. CAS: 949588-40-3
Synonyms: SCH 900435
Target:  

GlyT

Áreas de investigación:  

Metabolic Disease

Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse .
loading...
    loading...
Referencia número: HY-W041019R
No. CAS: 154-02-9
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse .
loading...
    loading...