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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1775 Results for "
protonatable backbone amines
" in MedChemExpress (MCE) Product Catalog:
Products (1775)
1775 Results for "protonatable backbone amines" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D1730
CAS No.: 1374019-99-4
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Research Areas:
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
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1 Cited Publications
Cat. No.: HY-W157376
CAS No.: 155773-72-1
Target:
PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems .
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1 Cited Publications
Cat. No.: HY-D1375
CAS No.: 2183440-44-8
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1 Cited Publications
Cat. No.: HY-D1540
CAS No.: 2097714-45-7
Synonyms: Cy 5.5 amine; Lumiprobe Cy 5.5 amine
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1 Cited Publications
Synonyms: N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine
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Research Areas:
ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
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1 Cited Publications
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Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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1
1 Cited Publications
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Methyltetrazine-amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates .
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1 Cited Publications
Cat. No.: HY-D1730A
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1 Cited Publications
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AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
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1 Cited Publications
Cat. No.: HY-D1050
CAS No.: 82321-04-8
Synonyms: 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
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1
1 Cited Publications
Cat. No.: HY-W013081
CAS No.: 132327-80-1
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1 Cited Publications
Cat. No.: HY-W591461
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
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1 Cited Publications
Cat. No.: HY-D1694
CAS No.: 1064123-31-4
1
1 Cited Publications
Cat. No.: HY-42360
CAS No.: 64987-85-5
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SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
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1 Cited Publications
Cat. No.: HY-D0049
CAS No.: 150810-69-8
Synonyms: 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester
1
1 Cited Publications
Synonyms: 3-O-methyl Dopamine-d4 hydrochloride
1
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Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
