1775 Results for "

protonatable backbone amines

" in MedChemExpress (MCE) Product Catalog:
Products (1775)

1775 Results for "protonatable backbone amines" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-W1048553B
Mal-PEG3400-NH2 TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
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1 Cited Publications
Cat. No.: HY-Y0470
CAS No.: 563-41-7
Synonyms: Aminourea hydrochloride; Hydrazinecarboxamide hydrochloride
Target:  

VAP-1

Semicarbazide hydrochloride is an orally active urea derivative. Semicarbazide hydrochloride binds to copper or iron in cells. Semicarbazide hydrochloride inhibits the activity of soluble semicarbazide sensitive amine oxidase (SSAO). Semicarbazide hydrochloride damages cartilage, blood vessels, ovaries, testicles, and thyroid follicles .
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1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
4-Bromo-7-azaindole is a brominated derivative of 7-azaindole. 4-Bromo-7-azaindole serves as a substrate for palladium-catalyzed C-N and C-O cross-coupling reactions, reacting with amides, amines, amino acid esters and phenols .
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1 Cited Publications
Cat. No.: HY-110098
CAS No.: 1110781-88-8
Purity:  99.85%
Synonyms: EPPTB
Ro 5212773 (EPPTB) is a potent and selective trace amine-associated receptor 1 (TAAR1) antagonist (Ki=0.9 nM for mouse TAAR1), with no significant effects on other TAARs. TAAR1 is a G protein-coupled receptor (GPCR) that is nonselectively activated by endogenous metabolites of amino acids .
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1 Cited Publications
Cat. No.: HY-D0017S
CAS No.: 1276379-68-0
Synonyms: DNSCl-d6
Dansyl chloride-d6 is the deuterium labeled Dansyl chloride (HY-D0017). Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .
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1 Cited Publications
Cat. No.: HY-118716
CAS No.: 105650-23-5
Purity:  99.93%
Synonyms: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) is the most abundant of generation of heterocyclic amines (HCA), resulted in the cooking of meat . DNA damaging and mutagenic activities. PhIP also has oestrogenic activity that could contribute to its tissue specific carcinogenicity .
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1 Cited Publications
Cat. No.: HY-117147A
CAS No.: 2517771-89-8
Purity:  99.69%
Target:  

REV-ERB Cytochrome P450

Research Areas:  

Metabolic Disease

GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism .
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1 Cited Publications
Cat. No.: HY-W127785
CAS No.: 1643-20-5
Synonyms: N,N-Dimethyldodecan-1-amine oxide; Dodecyldimethylamine oxide
Research Areas:  

Others

N,N-Dimethyldodecylamine N-oxide is an amine oxide surfactant commonly used as a detergent, emulsifier and wetting agent in various industrial processes, especially in personal care products and household cleaning in the production of agents. N,N-Dimethyldodecylamine N-oxide has unique chemical properties that make it an effective ingredient in many product formulations to help reduce surface tension and enhance cleaning power.
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1 Cited Publications
Cat. No.: HY-135233
CAS No.: 76931-93-6
Purity:  99.56%
Synonyms: SATA
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
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1 Cited Publications
Cat. No.: HY-NP001
Synonyms: Cationic Bovine Serum Albumin
Cationic BSA Protein (Cationic Bovine Serum Albumin) is a bovine serum albumin (BSA) modified with excess ethylenediamine, which has enhanced immunogenicity compared to native BSA. Positively charged primary amines block all negatively charged carboxyl groups, making Cationic BSA Protein a cationic protein. Cationic BSA Protein has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .
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1 Cited Publications
Cat. No.: HY-W036410
CAS No.: 13822-56-5
Synonyms: 3-Aminopropyltrimethoxysilane; APTMS
Research Areas:  

Others

Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane; APTMS) is an aminosilane coupling agent and self-assembled molecule that can form self-assembled monolayers or multilayers on the surfaces of silicon-based materials, platinum, pullulan (Viscosity (10%): 15-180 mPa.s) (HY-W145522), and magnesium alloys through silanization or amine-mediated adsorption, serving for surface functionalization and performance regulation. Aminopropyltrimethoxysilane is applicable in research related to biomedical materials, antibacterial materials, and corrosion protection .
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1 Cited Publications
Cat. No.: HY-137383
CAS No.: 102568-43-4
Purity:  99.72%
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals .
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1 Cited Publications
Cat. No.: HY-W016288
CAS No.: 7149-49-7
Synonyms: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde
Target:  

Fungal

Research Areas:  

Infection

Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
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1 Cited Publications
Cat. No.: HY-W016729
CAS No.: 6203-18-5
4-(Dimethylamino) cinnamaldehyde is a staining agent that reacts with flavan-3-ols and Proanthocyanidins (HY-N0794) bearing meta-dihydroxyl or trihydroxyl phenol structures to form a green chromophore. In acidic media, 4-(Dimethylamino) cinnamaldehyde undergoes a condensation reaction with aromatic primary amines to produce colored and stable quinoid protonated Schiff base salts. 4-(Dimethylamino) cinnamaldehyde can be used to determine indole products of apotryptophanase and tryptophanase, as well as for the detection and analysis of Proanthocyanidins, with the absorbance detection wavelength of the calibration curve set at 640 nm .
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1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
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Cat. No.: HY-140679
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG20000-NH2
mPEG20000-amine (mPEG20000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG20000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140676
CAS No.: 80506-64-5
Purity:  99.57%
Synonyms: mPEG2000-NH2
mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140677
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG5000-NH2
mPEG5000-amine (mPEG5000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG5000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-140675
CAS No.: 80506-64-5
Purity:  ≥98.0%
Synonyms: mPEG1000-NH2
mPEG1000-amine (mPEG1000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG1000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
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Cat. No.: HY-P3159
CAS No.: 1428885-83-9
Research Areas:  

Others

VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel .
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