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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
123 Results for "
beta-oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (123)
123 Results for "beta-oxidation" in MCE Product Catalog:
Cat. No.: HY-165098
CAS No.: 84796-61-2
Synonyms: β-Aminoisobutyric acid sodium salt; BAIBA sodium salt
Target:
Research Areas:
3-Aminoisobutyric acid (β-Aminoisobutyric acid) sodium salt has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid sodium salt increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid sodium salt attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK–PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid sodium salt is a catabolic metabolite of thymine and valine in skeletal muscle .
Cat. No.: HY-B0968AR
CAS No.: 5011-34-7
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Trimetazidine (Standard) is the analytical standard of Trimetazidine. This product is intended for research and analytical applications. Trimetazidine is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine triggers autophagy. Trimetazidine is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor .
Cat. No.: HY-N2021AR
CAS No.: 164204-38-0
Category:
Cat. No.: HY-F0001A
CAS No.: 1949720-50-6
Synonyms: Disodium NADH hydrate
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
NADH disodium hydrate (Disodium NADH hydrate) is an orally effective reduced coenzyme. NADH disodium hydrate plays a role in regenerating electron donors during cellular energy metabolism, including glycolysis, β-oxidation, and the tricarboxylic acid (TCA) cycle. NADH disodium hydrate regulates calcium homeostasis by promoting the opening of IP3-gated Ca 2+ channels and inhibiting Ryanodine receptor, and affects mitochondrial function through direct interaction with VDAC. NADH disodium hydrate is used in cytoprotective studies related to cerebral ischemic injury, neurodegenerative diseases, aging, and signal transduction .
Cat. No.: HY-149545
CAS No.: 214038-32-1
Synonyms: 1,3-Dipalmitoyl-2-docosahexaenoyl glycerol
Research Areas:
1,3-Palmitin-2-docosahexaenoin (1,3-Dipalmitoyl-2-docosahexaenoyl glycerol) is the isomer of triacylglycerol (TAG), in which docosahexaenoic acid (DHA) is located at the β position (sn-2) of the glycerol backbone. 1,3-Palmitin-2-docosahexaenoin inhibits fatty acid synthase and cholesterol metabolism enzymes, activates carnitine palmitoyltransferase (CPT) in liver mitochondria and promotes β-oxidation of fatty acids. 1,3-Palmitin-2-docosahexaenoin exhibits lipid metabolism regulating activity .
Cat. No.: HY-N0396R
CAS No.: 19210-12-9
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Cat. No.: HY-W012974R
CAS No.: 144-90-1
Synonyms: β-Aminoisobutyric acid (Standard); BAIBA (Standard)
Research Areas:
3-Aminoisobutyric acid (Standard) is the analytical standard of 3-Aminoisobutyric acid. This product is used for research and analytical applications. 3-Aminoisobutyric acid (β-Aminoisobutyric acid) exhibits anti-inflammatory and antioxidant effects. It increases the expression of brown fat cell-specific genes in white adipose tissue and enhances fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid alleviates insulin resistance and inflammation induced by palmitic acid or a high-fat diet in mice via the AMPK–PPARδ-dependent pathway. 3-Aminoisobutyric acid is a catabolite of thymine and valine in skeletal muscle .
Cat. No.: HY-113165AR
CAS No.: 6920-31-6
Cat. No.: HY-N17761A
CAS No.: 62828-25-5
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Cat. No.: HY-113201S
CAS No.: 2245713-18-0
Cat. No.: HY-W754236
Cat. No.: HY-B1520
CAS No.: 24818-79-9
Synonyms: Aluminum clofibrate
Aluminium clofibrate is an orally active peroxisome proliferator. Aluminium clofibrate increases peroxisomal β-oxidation enzyme activities, elevates catalase. Aluminium clofibrate can be used in the research of cancer .
Cat. No.: HY-152016S
CAS No.: 2692624-07-8
Synonyms: (±)-Carnitin-d9 hydrochloride
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Octanoylcarnitine is an orally active medium-chain acylcarnitine transport intermediate in fatty acid β-oxidation. Octanoylcarnitine is converted to octanoyl-CoA by carnitine acetyltransferase (CrAT), which then generates energy via β-oxidation in mitochondria of the heart and skeletal muscle. Octanoylcarnitine enhances grip strength and treadmill endurance, alleviates lactic acidosis, distributes in muscle and heart tissues, increases free carnitine levels, and mitigates mitochondrial stress. Octanoylcarnitine is associated with long-chain fatty acid metabolism, shows a positive correlation with subcutaneous fat area in patients with metastatic pancreatic ductal adenocarcinoma, and is closely related to central retinal artery occlusion (CRAO) .
Cat. No.: HY-113261S1
Cat. No.: HY-W400421
CAS No.: 58888-84-9
Synonyms: 3-Hydroxy VPA
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3-Hydroxyvalproic acid (3-Hydroxy VPA) is a metabolite of valproic acid. 3-Hydroxyvalproic acid is a weak inhibitor of enzymes related to the mitochondrial β-oxidation pathway. 3-Hydroxyvalproic acid is promising for research of diseases related to abnormal valproic acid metabolism .
Cat. No.: HY-E71595
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2-Methylisocitrate dehydratase (EC 4.2.1.99) is a 3-hydroxybutyryl-CoA dehydratase belonging to the carbon-oxygen lyase subclass of lyases. It catalyzes the dehydration of 3-hydroxybutyryl-CoA to form crotonyl-CoA and is a key enzyme in butyrate metabolism, fatty acid β-oxidation, and polyhydroxybutyrate (PHB) metabolism.
Cat. No.: HY-50202AR
CAS No.: 828934-41-4
Synonyms: (R)-(+)-Etomoxir sodium salt (Standard)
Research Areas:
Etomoxir sodium salt (Standard) is the analytical standard of Etomoxir sodium salt (HY-50202A). This product is intended for research and analytical applications. Etomoxir((R)-(+)-Etomoxir) sodium salt is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig .
Cat. No.: HY-CE01083
CAS No.: 172324-59-3
Synonyms: 3α,7α,12α-Trihydroxy-24-oxo-5β-cholestan-26-oyl-CoA
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Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
