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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
156 Results for "
RNA-binding cleft
" in MedChemExpress (MCE) Product Catalog:
Products (156)
156 Results for "RNA-binding cleft" in MCE Product Catalog:
Cat. No.: HY-P703240
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TAF15; HTAFII68; Prev. TAF2N; TATA Box-binding Protein-Associated Factor 2N (RNA-binding Protein 56); RBP56; 68 KDa TATA-binding Protein-Associated Factor; Npl3; TBP-Associated Factor 15; TATA Box binding Protein (TBP)-Associated Factor, RNA Polymerase II
Species:
Human
Source:
E. coli
Cat. No.: HY-P87046
Synonyms: DKFZp586I0923 antibody; HKQ antibody; Homolog of mouse quaking QKI KH domain RNA binding protein antibody; Hqk antibody; HQK1 antibody; HqkI antibody; OTTHUMP00000017581 antibody; OTTHUMP00000017582 antibody; OTTHUMP00000017583 antibody; Protein quaking antibody; DKFZp586I0923 antibody; HKQ antibody; Homolog of mouse quaking QKI KH domain RNA binding protein antibody; Hqk antibody; HQK1 antibody; HqkI antibody; OTTHUMP00000017581 antibody; OTTHUMP00000017582 antibody; OTTHUMP00000017583 antibody; Protein quaking antibody; QK antibody; QK1 antibody; QK3 antibody; QKI antibody; QKI_HUMAN antibody; QKI1 antibody; Quaking homolog antibody; Quaking homolog KH domain RNA binding antibody; Quaking homolog KH domain RNA binding mouse antibody; Quaking isoform 1 antibody; Quaking protein antibody; RNA binding protein HQK antibody;
Cat. No.: HY-P87045
Synonyms: DKFZp586I0923 antibody; HKQ antibody; Homolog of mouse quaking QKI KH domain RNA binding protein antibody; Hqk antibody; HQK1 antibody; HqkI antibody; OTTHUMP00000017581 antibody; OTTHUMP00000017582 antibody; OTTHUMP00000017583 antibody; Protein quaking antibody; DKFZp586I0923 antibody; HKQ antibody; Homolog of mouse quaking QKI KH domain RNA binding protein antibody; Hqk antibody; HQK1 antibody; HqkI antibody; OTTHUMP00000017581 antibody; OTTHUMP00000017582 antibody; OTTHUMP00000017583 antibody; Protein quaking antibody; QK antibody; QK1 antibody; QK3 antibody; QKI antibody; QKI_HUMAN antibody; QKI1 antibody; Quaking homolog antibody; Quaking homolog KH domain RNA binding antibody; Quaking homolog KH domain RNA binding mouse antibody; Quaking isoform 1 antibody; Quaking protein antibody; RNA binding protein HQK antibody; QKI-6
Cat. No.: HY-P71819
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ELAVL3; ELAV Like Neuron-Specific RNA binding Protein 3; ELAV Like RNA binding Protein 3; DKFZp547J036; PLE21; Hu Antigen C; HUC; Hu-Antigen C; Paraneoplastic Cerebellar Degeneration-Associated Antigen; MGC20653; Paraneoplastic Limbic Encephalitis Antigen
Species:
Human
Source:
P. pastoris
Cat. No.: HY-B1315S
CAS No.: 1433961-56-8
Target:
Isotope-Labeled Compounds Insecticide Cholinesterase (ChE) Reactive Oxygen Species (ROS) Apoptosis
Research Areas:
Carbaryl-d3 is the deuterium labeled Carbaryl (HY-B1315). Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide .
X
Target:
Cat. No.: HY-W012735
CAS No.: 59045-82-8
Synonyms: (+)-β-Homoproline; (+)-Hexahydronicotinic acid; (+)-3-Carboxypiperidine
Target:
Research Areas:
(+)-Nipecotic acid ((+)-β-Homoproline) is a GABA transport inhibitor with potential antidepressant and anxiolytic activities. (+)-Nipecotic acid can increase the concentration of GABA in the synaptic cleft, thereby enhancing inhibitory neurotransmission. The research on (+)-Nipecotic acid provides a possible direction for the development of new inhibitory compounds for psychiatric diseases .
Cat. No.: HY-P5959
Target:
Research Areas:
Cat. No.: HY-101112
CAS No.: 137018-54-3
Category:
Target:
Cat. No.: HY-187623
CAS No.: 149607-21-6
Target:
Research Areas:
U 92163 is an HIV-2 protease inhibitor. It is a synthetic peptidomimetic transition-state analog. U 92163 binds in an extended conformation along the length of the enzyme's binding cleft, and forms hydrogen bonds with the catalytic aspartate pair and other protease residues to block enzyme activity. U 92163 can be used in research on acquired immunodeficiency syndrome (AIDS) .
ASN03576800 could be a potent inhibitor for Ebola virus matrix protein VP40 in process of viral assembly and budding process. ASN03576800 occupies the RNA binding region of VP40 .
Cat. No.: HY-21997
CAS No.: 136834-22-5
Synonyms: NS-2330
Research Areas:
Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC50=6.5 nM), norepinephrine (NE;IC50=1.7 nM), and serotonin (5-HT;IC50=11 nM), and with potentials as an anti-obesity agent . Tesofensine is a CNS acting anti-obesity agent .
Cat. No.: HY-174462
Target:
Research Areas:
AChE-IN-90 (Compound 5b) is an orally active, brain-penetrant and potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.023 μM against human AChE and lower selectivity for butyrylcholinesterase (BuChE) (IC50 1.8 μM). AChE-IN-90 increases acetylcholine levels in the synaptic cleft. AChE-IN-90 is promising for research of neurodegenerative diseases such as Alzheimer's disease .
Cat. No.: HY-176471
CAS No.: 3070282-38-8
Target:
Research Areas:
IGF2BP3-IN-1 (Compound I3IN-122) is an IGF2BP3 (a RNA binding protein) inhibitor (IC50: > 50 μM), and can be used for cancer research .
Category:
Polysaccharides Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides
Target:
Cat. No.: HY-183876
CAS No.: 661482-39-9
Target:
Research Areas:
LAF-153 is a Methionine Aminopeptidase-2 (MetAP-2) inhibitor with human IC50 values of 0.074 μM and 0.16 μM.LAF-153 has a t-butyl group extending into the innermost portion of the MetAP-2 cleft, a lactam ring coordinated in the enzyme’s shallow surface pocket, and three hydroxyl groups coordinating to the two cobalt ions in the enzyme’s active site .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
