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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
204 Results for "
cluster
" in MedChemExpress (MCE) Product Catalog:
Products (204)
204 Results for "cluster" in MCE Product Catalog:
Cat. No.: HY-117123
CAS No.: 37206-04-5
Category:
Cat. No.: HY-149035
Research Areas:
PAA4 is a hypercoordinate carbon-centered tetranuclear gold (I) cluster prodrug . PAA4 releases active Au (I) ions upon triggering by GSH (HY-D0187), and this process is accelerated in the acidic microenvironment of bladder cancer cells with high GSH expression. PAA4 inhibits the activities of cytosolic TrxR1 and mitochondrial TrxR2, inducing ROS accumulation, lipid peroxidation, ferroptosis, loss of mitochondrial membrane potential and DNA damage. PAA4 can be used in bladder cancer-related research .
Cat. No.: HY-P0131A
CAS No.: 2828432-44-4
Synonyms: Laminin (925-933) TFA
Target:
Research Areas:
Laminin peptide CDPGYIGSR TFA (Laminin (925-933) TFA) is a peptide fragment derived from the laminin B1 chain that binds to laminin receptors, and acts as a ligand for the laminin receptor. Laminin peptide CDPGYIGSR TFA mediates cell spreading, induces the clustering of receptors with vinculin and α-actinin, regulates the actin cytoskeleton, promotes the formation of stress fibers, and enhances epithelial cell adhesion. Laminin peptide CDPGYIGSR TFA can be used in studies related to tumor metastasis and nerve injury .
Cat. No.: HY-P991529
Target:
Research Areas:
Cat. No.: HY-P72328
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2AC4; Histone H2A Type 1-B/E; Prev. HIST1H2AB; Histone H2A/M; Prev. H2AFM; HIST1H2AE; H2A/M; Histone H2A/A; Histone cluster 1 H2A Family Member B; Histone H2A.2; H2A Histone Family, Member M; Histone H2A; Histone cluster 1, H2ab; H2AFA; H2A clustered His
Species:
Human
Source:
E. coli
Cat. No.: HY-P703142
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2BC5; Histone H2B.K; Prev. HIST1H2BD; DJ221C16.6; Prev. H2BFB; HIST1H2BI; H2B/B; HIST1H2BG; Histone cluster 1 H2B Family Member D; HIST1H2BF; H2B Histone Family, Member B; HIST1H2BC; HIRA-Interacting Protein 2; HIST1H2BE; Histone cluster 1, H2bd; H2B.1B
Species:
Human
Source:
E. coli
Cat. No.: HY-100847
CAS No.: 1825345-52-5
AZ0108 is an inhibitor for poly ADP-ribose polymerase (PARP), which inhibits PARP1, PARP2, PARP3, PARP6, TNKS1, TNKS2, with IC50s of <0.03, <0.03, 2.8, 0.083, 3.2, >3 μM, respectively. AZ0108 prevents centrosome clustering with an EC50 of 0.053 μM, and exhibits cytotoxicity in cell OCI-LY-19 with GI50 of 0.017 μM. AZ0108 exhibits good in vivo pharmacokinetic characters in rat/mouse models .
Cat. No.: HY-156533
CAS No.: 2708279-78-9
Target:
Research Areas:
5-HT2 agonist-1 (Compound 24) is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
Cat. No.: HY-156533A
CAS No.: 2708279-77-8
Target:
Research Areas:
5-HT2 agonist-1 (Compound 24) free base is a 5-HT2A & 5-HT2B & 5-HT2C agonist, with IC50s of 10 nM, 8.3, and 1.6 nM respectively. 5-HT2 agonist-1 free base can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
Cat. No.: HY-P99431
CAS No.: 2489390-15-8
Synonyms: Alomfilimab; SAR 445256
Target:
Research Areas:
Target:
Research Areas:
5-HT2A&5-HT2C agonist-1 (Example 2) is a 5-HT2A & 5-HT2C agonist, with IC50s of 196 nM and 0.9 nM respectively. 5-HT2A&5-HT2C agonist-1 can be used for research of depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headache, PTSD, seizure disorders and other CNS disorders .
Cat. No.: HY-16031A
CAS No.: 468719-53-1
Synonyms: NSC710464
Research Areas:
AFP464 (NSC710464) is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 is applicable to research related to breast cancer .
Cat. No.: HY-16031B
Synonyms: NSC710464 dihydrochloride
Research Areas:
AFP464 (NSC710464) dihydrochloride is a prodrug of Aminoflavone (HY-132974) and an agonist of the aryl hydrocarbon receptor (AhR). AFP464 dihydrochloride downregulates the expression of α6-integrin (α6-integrin), inhibits breast tumor growth, reduces the population of tumor-initiating cells, disrupts mammosphere structure, induces the formation of mucin lake clusters, triggers DNA damage, and exerts antiproliferative activity. AFP464 dihydrochloride is rapidly converted to Aminoflavone by nonspecific esterases in plasma and cell culture media. AFP464 dihydrochloride is applicable to research related to breast cancer .
Cat. No.: HY-P5912
Target:
Research Areas:
Cat. No.: HY-P72335
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H3C1; Histone H3/C; Prev. HIST1H3A; HIST1H3J; Prev. H3FA; HIST1H3I; H3/A; HIST1H3H; Histone cluster 1 H3 Family Member A; HIST1H3G; H3 Histone Family, Member A; HIST1H3F; Histone cluster 1, H3a; HIST1H3E; Histone 1, H3a; HIST1H3D; Histone H3.1; HIST1H3B;
Species:
Human
Source:
E. coli
Cat. No.: HY-P72336
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H4C1; H4/B; Prev. HIST1H4A; H4/G; Prev. H4FA; H4FI; Histone H4; H4/I; Histone cluster 1 H4 Family Member A; H4/A; H4 Histone Family, Member A; H4/J; Histone cluster 1, H4a; H4FJ; Histone 1, H4a; H4/C; HIST1H4J; H4FC; HIST1H4D; H4/H; HIST1H4C; H4FH; HIST1H
Species:
Xenopus laevis
Human
Source:
E. coli
Cat. No.: HY-P72798
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: H3C1; Histone H3/C; Prev. HIST1H3A; HIST1H3J; Prev. H3FA; HIST1H3I; H3/A; HIST1H3H; Histone cluster 1 H3 Family Member A; HIST1H3G; H3 Histone Family, Member A; HIST1H3F; Histone cluster 1, H3a; HIST1H3E; Histone 1, H3a; HIST1H3D; Histone H3.1; HIST1H3B;
Species:
Human
Source:
E. coli
Cat. No.: HY-P71005
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLAMF9; CD2F10; SLAM Family Member 9; Signaling Lymphocytic Activation Molecule Family Member 2001; CD2F-10; Signaling Lymphocytic Activation Molecule Family Member 9; CD84-H1; cluster Of Differentiation 2 Antigen Family Member 10; SF2001; cluster Of Diff
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P99605
CAS No.: 2218515-90-1
Synonyms: PRS 343
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
