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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1537 Results for "
D2
" in MedChemExpress (MCE) Product Catalog:
Products (1537)
1537 Results for "D2" in MCE Product Catalog:
Cat. No.: HY-B0389S41
CAS No.: 30737-83-8
Synonyms: Glucose-2-d; D-(+)-Glucose-2-d; Dextrose-2-d
Cat. No.: HY-P10847
CAS No.: 2549046-46-8
Cat. No.: HY-N15735
CAS No.: 219986-51-3
Synonyms: 2-Caffeoylpiscidic acid
Target:
Cat. No.: HY-153660S
Synonyms: MC-4R Agonist 2-d8
Cat. No.: HY-12772S4
Synonyms: (2S)-R-63373-d8
Cat. No.: HY-189060
CAS No.: 3065124-09-3
Target:
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SLU-12091 is a phosphodiesterase (PDE) inhibitor and the more potent enantiomer of rac-11. SLU-12091 inhibits the activities of hPDE5, hPDE11, hPDE2A1, hPDE3A, hPDE3B, hPDE4A1A and hPDE4D2. SLU-12091 inhibits the growth of Cryptosporidium parvum without inhibiting the growth of host cells at the highest concentration tested. SLU-12091 can be used for the research of cryptosporidiosis .
Cat. No.: HY-W704805
Cat. No.: HY-103050R
CAS No.: 1013750-77-0
Research Areas:
ML-030 (Standard) is the analytical standard of ML-030 (HY-103050). This product is intended for research and analytical applications. ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively.
Synonyms: Ro 03-7410-d9
Cat. No.: HY-122942R
CAS No.: 56317-21-6
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NAB-14 is a potent, selective, orally active and non-competitive GluN2C/2D antagonists with an IC50 of 580 nM for GluN1/GluN2D. NAB-14 shows >800-fold selective for recombinant GluN2C and GluN2D over GluN2A and GluN2B. NAB-14 can cross the blood-brain-barrier .
Cat. No.: HY-12772S6
Synonyms: (2S,4R)-R-63373-d6
Research Areas:
(2R,4S)-Hydroxy Itraconazole-d6 ((2R,4S)-R-63373-d6) is the deuterated-labeled (2S,4R)-Hydroxy Itraconazole (HY-12772). (2S,4R)-Hydroxy Itraconazole ((2S,4R)-R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
Cat. No.: HY-128453
CAS No.: 1185486-16-1
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LRH-1 antagonist-1 (Compound 3d2) is a LRH-1 antagonist with a Kd of 1.8 μM. LRH-1 antagonist-1 inhibits the transcriptional activity of LRH-1 and reduces the expression of G0S2. LRH-1 antagonist-1 inhibits the proliferation of LRH-1-positive cancer cells. LRH-1 antagonist-1 can be used for research on pancreatic cancer, colon cancer and breast cancer .
Cat. No.: HY-128453A
CAS No.: 2932459-63-5
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LRH-1 antagonist-1 (Compound 3d2) dihydrochloride is a LRH-1 antagonist with a Kd of 1.8 μM. LRH-1 antagonist-1 dihydrochloride inhibits the transcriptional activity of LRH-1 and reduces the expression of G0S2. LRH-1 antagonist-1 dihydrochloride inhibits the proliferation of LRH-1-positive cancer cells. LRH-1 antagonist-1 dihydrochloride can be used for research on pancreatic cancer, colon cancer and breast cancer .
Cat. No.: HY-15780A
CAS No.: 913612-38-1
Synonyms: OPC-34712 hydrochloride
Research Areas:
Brexpiprazole (OPC-34712) hydrochloride, an atypical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole hydrochloride is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM. Brexpiprazole hydrochloride also shows potent antagonist activity at human noradrenergic α1B (Ki=0.17 nM) and α2C receptors (Ki=0.59 nM) [2].
Cat. No.: HY-187538
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Research Areas:
DR/5-HT7AR Ligand-1 is a ligand with a Ki value of 1.24 nM against human D2R, 5.78 nM against human D3R, 0.67 nM against human 5-HT1AR, and 19.9 nM against human 5-HT7AR. DR/5-HT7AR Ligand-1 can be used for the research of schizophrenia .
Synonyms: N-FMOC-leucine; NPC 15199; NSC 334290
Target:
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Fmoc-Leucine (N-FMOC-leucine) is an anti-inflammatory agent that not only promotes extracellular Ca 2+ influx but also facilitates intracellular Ca 2+ release. Fmoc-Leucine is a selective ligand for PPARγ (Ki = 15 μM), exhibiting insulin-sensitizing effects but with weak fatogenic activity. Fmoc-Leucine exhibits unique self-assembly properties and can form transient gels, stable gels, or crystals/2D sheets through different pathways. Fmoc-Leucine can be used in the research of diabetes, colitis, and bladder cancer [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
