195 Results for "

fluorogenic substrates

" in MedChemExpress (MCE) Product Catalog:
Products (195)

195 Results for "fluorogenic substrates" in MCE Product Catalog:

Cat. No.: HY-P4466
CAS No.: 130877-92-8
Target:  

HIV Protease

Research Areas:  

Infection

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity .
loading...
    loading...
Cat. No.: HY-W753820A
Synonyms: Boc-Leu-Arg-Arg-AMC TFA
Research Areas:  

Others

Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
loading...
    loading...
Cat. No.: HY-D0146
CAS No.: 87687-02-3
Synonyms: BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO - detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm .
loading...
    loading...
Cat. No.: HY-P0019B
CAS No.: 66216-79-3
Research Areas:  

Others

Z-Gly-Gly-Arg-AMC TFA is the TFA salt form of Z-Gly-Gly-Arg-AMC (HY-P0019). Z-Gly-Gly-Arg-AMC TFA is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .
loading...
    loading...
Cat. No.: HY-P10162A
Target:  

Caspase

Research Areas:  

Others

Ac-DMQD-AMC TFA is a fluorogenic substrate for caspase-3 or caspase-10. Similar to Ac-DEVD-AMC, it releases the AMC (7-amino-4-methylcoumarin) fluorophore, resulting in fluorescence. Ac-DMQD-AMC TFA can be used to measure caspase activity in in vitro apoptosis monitoring .
loading...
    loading...
Cat. No.: HY-P2296
Target:  

Fluorescent Dye

Research Areas:  

Others

Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection .
loading...
    loading...
Cat. No.: HY-P2628
CAS No.: 161877-70-9
Target:  

Fluorescent Dye

Research Areas:  

Others

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K + deprivation-induced apoptosis of cerebellar granule neurons .
loading...
    loading...
Cat. No.: HY-P4400
CAS No.: 219138-08-6
Target:  

Fluorescent Dye

Research Areas:  

Others

Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals .
loading...
    loading...
Cat. No.: HY-P4416
CAS No.: 577969-56-3
Target:  

Fluorescent Dye

Research Areas:  

Others

Ac-Gly-Ala-Lys(Ac)-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Gly-Ala-Lys(Ac)-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
loading...
    loading...
Cat. No.: HY-P4419A
Target:  

Fluorescent Dye

Research Areas:  

Others

Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
loading...
    loading...
Cat. No.: HY-P5380
CAS No.: 193475-71-7
Synonyms: Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2
Target:  

MMP Fluorescent Dye

Research Areas:  

Others

TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm) .
loading...
    loading...
Cat. No.: HY-P5380A
Synonyms: Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2 TFA
Target:  

MMP Fluorescent Dye

Research Areas:  

Cancer

TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) TFA is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 TFA can specifically detect MMP activity (Ex/Em = 340/485 nm) .
loading...
    loading...
Cat. No.: HY-P4403
CAS No.: 223538-61-2
Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Research Areas:  

Others

Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
loading...
    loading...
Cat. No.: HY-135036
CAS No.: 17695-46-4
Purity:  99.46%
Synonyms: 4-MUB
Research Areas:  

Others

4-Methylumbelliferyl butyrate (4-MUB) is a fluorogenic esterase substrate that is hydrolyzed by esterases to release the fluorescent product 4-methylumbelliferone (HY-N0187). 4-Methylumbelliferyl butyrate is hydrolyzed by the general esterases (GE) of Daphnia magna and Chironomus riparius; it also serves as a substrate for the recombinant mycobacterial carboxylesterase MT2282 (CaeA). 4-Methylumbelliferyl butyrate is used to determine the activity of the S. aureus serine hydrolases FphB and FphH. 4-Methylumbelliferyl butyrate is used in studies related to esterase activity assays .
loading...
    loading...
Cat. No.: HY-P5272
CAS No.: 112844-49-2
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant Ki of 1.98 μM .
loading...
    loading...
Cat. No.: HY-P11325
Research Areas:  

Others

Ac-RR-AFC TFA is a Cathepsin B fluorogenic substrate (Ex=400 nm, Em=505 nm). Cathepsin B activity in cells lysates is determined by measuring cleavage of Ac-RR-AFC TFA and its cleavage occurs at the RR-AFC amide bond. Ac-RR-AFC TFA can be used for activity assays and mechanistic studies on cathepsin B .
loading...
    loading...
Cat. No.: HY-P3106
CAS No.: 149695-85-2
Synonyms: (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110
Target:  

Fluorescent Dye

Research Areas:  

Others

(Z-Ala-Ala-Ala-Ala)2Rh110 is a sensitive fluorogenic elastase substrate. The colorless and nonfluorescent (Z-Ala-Ala-Ala-Ala)2Rh110 is selectively cleaved by elastase to yield the highly fluorescent compound rhodamine 110, which can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525 nm.
loading...
    loading...
Cat. No.: HY-P2176A
Synonyms: Z-Leu-Arg-Gly-Gly-AMC TFA
Target:  

Fluorescent Dye

Research Areas:  

Others

Z-LRGG-AMC TFA is the trifluoroacetate salt of Z-LRGG-AMC (HY-P2176). Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon cleavage of Z-LRGG-AMC TFA by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify isopeptidase T activity (Ex/Em : 360/460 nm) .
loading...
    loading...
Cat. No.: HY-138658
Synonyms: JF526, SE; JF526, NHS
Janelia Fluor 526, SE (JF526,SE) is a fluorogenic yellow fluorescent dye that contains NHS ester group. JF526 is a versatile scaffold for fluorogenic ligands, including labels for genetically encoded self-labeling protein tags and stains for endogenous structures . Janelia Fluor fluorescent dyes can be chemically conjugated to the specific HaloTag substrate (a chloroalkane ligand) to form a fluorescent ligand, rather than binding directly to the HaloTag protein itself. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute (Ex/Em = 526/550 nm).
loading...
    loading...
Cat. No.: HY-169491
CAS No.: 1224691-12-6
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively .
loading...
    loading...