17 Results for "

4-MU

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "4-MU" in MCE Product Catalog:

74
74 Publications Verification
Cat. No.: HY-19707
CAS No.: 14003-96-4
Synonyms: IRE1 Inhibitor III
Target:  

IRE1

Research Areas:  

Metabolic Disease

8C (IRE1 Inhibitor III) is a small-molecule inhibitor of IRE1α.
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8
8 Cited Publications
Cat. No.: HY-N0187
CAS No.: 90-33-5
Synonyms: Hymecromone; 4-MU
4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
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8
8 Cited Publications
Cat. No.: HY-N0187A
CAS No.: 5980-33-6
Synonyms: Hymecromone sodium salt; 4-MU sodium salt
Research Areas:  

Cancer

4-Methylumbelliferone (sodium salt) is a coumarin derivative. 4-Methylumbelliferone (sodium salt) can be used as a standard to quantify the free 4-methylumbelliferone released as a result of enzyme-substrate action. 4-Methylumbelliferone (sodium salt) inhibits hyaluronan production in vitro. 4-Methylumbelliferone (sodium salt) can be studied in ovarian cancer research .
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2
2 Cited Publications
Cat. No.: HY-W019823
CAS No.: 76204-02-9
4-MUNANA is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
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Cat. No.: HY-123633
CAS No.: 18997-57-4
Purity:  99.87%
Target:  

Glycosidase

Research Areas:  

Others

4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity . 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively .
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Cat. No.: HY-118135
CAS No.: 38597-12-5
Purity:  99.76%
Synonyms: 4MU-α-Gal
Target:  

Fluorescent Dye

Research Areas:  

Others

4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .
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Cat. No.: HY-137873
CAS No.: 17833-43-1
Purity:  99.99%
Synonyms: 4-Methylumbelliferyl-α-D-Glucose; 4-Methylumbelliferyl-α-D-Glucoside; 4-MU-α-D-Glucopyranoside
Research Areas:  

Others

4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase, which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. 4-Methylumbelliferyl-α-D-Glucopyranoside can be used as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
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Cat. No.: HY-N0187R
CAS No.: 90-33-5
Synonyms: Hymecromone (Standard); 4-MU (Standard)
4-Methylumbelliferone (Standard) is the analytical standard of 4-Methylumbelliferone. This product is intended for research and analytical applications. 4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
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Cat. No.: HY-135036
CAS No.: 17695-46-4
Purity:  99.46%
Target:  

Fluorescent Dye

Research Areas:  

Others

4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187) .
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Cat. No.: HY-DY1034
CAS No.: 76204-02-9
4-MUNANA (solution) is a substrate of influenza virus neuraminidase (NA) with high selectivity and irreversible reaction. In the enzymatic reaction, 4-MUNANA is hydrolyzed by NA to generate fluorescent 4-methylumbelliferone (4-MU). By detecting the fluorescence intensity of 4-MU, quantitative analysis of NA activity can be achieved. 4-MUNANA can be used in influenza-related research, such as screening NA inhibitors, developing new anti-influenza drugs, and studying the infection mechanism of influenza viruses .
Solvent and Concentration: Sterile water: 10 mM
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Cat. No.: HY-D1632
CAS No.: 460085-45-4
4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH2. 4-MU-α-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .
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Cat. No.: HY-W654272
CAS No.: 2181774-46-7
Synonyms: 4-MU-α-idoa 2-sulfate sodium
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .
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Cat. No.: HY-144609
CAS No.: 2773925-74-7
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Mu opioid receptor antagonist 4 (compound 31) is a potent and selective μ opioid receptor (MOR) antagonist with a Ki of 0.38 nM and an EC50 of 1.07 nM. Mu opioid receptor antagonist 4 has remarkable CNS antagonism against morphine, and precipitated fewer withdrawal symptoms than Naloxone. Mu opioid receptor antagonist 4 Mu opioid receptor antagonist 4 can be used for researching opioid use disorders (OUD) .
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Cat. No.: HY-137321
CAS No.: 15087-06-6
Synonyms: Estriol 3-β-D-Glucuronide sodium salt
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Estriol 3-glucuronide (Estriol 3-β-D-Glucuronide) sodium salt is a metabolite of Estriol. Estriol 3-glucuronide sodium salt competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide (4Mu-GlcU). Estriol 3-glucuronide sodium salt is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc) .
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Cat. No.: HY-156020
CAS No.: 851185-20-1
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Glucocerebrosidase-IN-2 (compound 12) is a quinazoline analogue and an inhibitor of glucocerebrosidase (GC). Glucocerebrosidase-IN-2 has the potential to improve GC translocation to lysosomes in Gaucher disease patient-derived cells (mostly carrying the N370S mutation). Glucocerebrosidase-IN-2 inhibits the hydrolysis of 4-methylumbelliferone β-D-glucopyranoside (4MU) and fluorescent glycosylceramide (FlourGC) in N370S mutant tissues with an AC50 of 25.29 μM .
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Cat. No.: HY-N0187S
CAS No.: 1569304-40-0
Synonyms: Hymecromone-13C4; 4-MU-13C4
4-Methylumbelliferone- 13C4 (Hymecromone- 13C4) is the 13C-labeled 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
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Cat. No.: HY-W998838
CAS No.: 333719-47-4
Target:  

MOFs

Research Areas:  

Others

Copper, triaqua[μ-[5'-(4-carboxyphenyl)[1,1':3',1''-terphenyl]-4,4''-dicarboxylato(3-)-κO4:κO4']][μ3-[5'-(4-carboxyphenyl)[1,1':3',1''-terphenyl]-4,4''-dicarboxylato(3-)-κO4:κO4':κO4'']]tri- is a metal-organic framework (MOF).
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