13 Results for "

A-ring

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "A-ring" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-12545
CAS No.: 85079-48-7
Synonyms: PbTx-3
Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na + channel activator and has multiple active centers (A-ring lactone, C-42 of R side chain) . Brevetoxin-3 (PbTx-3) has a high affinity to site 5 of the voltage-sensitive Na + channels, inhibits the inactivation of Na + channels and prolongs the mean open time of these channels. Brevetoxin-3 (PbTx-3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation .
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Cat. No.: HY-N3200
CAS No.: 53734-74-0
Neorauflavane is a tyrosinase inhibitor with mushroom tyrosinase IC50 values of 30 nM and 500 nM, and Ki values of 19 nM and 130 nM. Neorauflavane inhibits monophenolase and diphenolase activities, binds to tyrosinase’s active site via its B-ring resorcinol motif and A-ring methoxy group. Neorauflavane reduces melanin synthesis in melanoma cells. Neorauflavane can be used for the research of skin hyperpigmentation .
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Cat. No.: HY-N8810
CAS No.: 917482-67-8
Target:  

Others

Research Areas:  

Others

Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
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Cat. No.: HY-135755
CAS No.: 64053-02-7
Target:  

Drug Intermediate

Research Areas:  

Others

δ-Lactone, an A-ring degradation product, is also an important intermediate in the synthesis of Estrone (HY-B0234), Estradiol (HY-B0141), and their derivatives .
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Cat. No.: HY-N1256
CAS No.: 1169806-02-3
Sculponeatic acid is a new A-ring contracted oleanane triterpene that can be isolated from Isodon sculponeata .
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Cat. No.: HY-P84499
Synonyms: RNF1; ring1A

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84499A
Synonyms: RNF1; ring1A

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P82606
Synonyms: ring1A; ring1; ring1A; Rnf1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-128131
CAS No.: 2110-25-0
Target:  

Endogenous Metabolite

Research Areas:  

Others

UCCF-029 Free base is a potent activator of the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. UCCF-029 Free base exhibits enhanced activity through benzannulation of the flavone A-ring at the 7,8-position. UCCF-029 Free base serves as a structural guide for the development of more effective flavonoid analogues. UCCF-029 Free base demonstrates improved potency compared to apigenin in activating wild-type CFTR. UCCF-029 Free base also exhibits potential for activating the mutant CFTR (G551D-CFTR) though not as robustly as apigenin.
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Cat. No.: HY-180503
CAS No.: 284041-36-7
Target:  

VD/VDR

Research Areas:  

Endocrinology

19-Nor-22-oxa-1a,25(OH)2-VD3 is a vitamin D₃ analogue. 19-Nor-22-oxa-1a,25(OH)2-VD3 has an extremely low affinity for the vitamin D receptor (VDR) and hardly binds to the vitamin D binding protein (DBP). 19-Nor-22-oxa-1a,25(OH)2-VD3 can effectively induce the differentiation of HL-60 cells and cause G₀-G₁ phase cell cycle arrest. 19-Nor-22-oxa-1a,25(OH)2-VD3 can be used to study diseases such as excessive hyperparathyroidism .
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Cat. No.: HY-P810963
Synonyms: KIAA0161, RNF144, UBCE7IP4, RNF144A, E3 ubiquitin-protein ligase RNF144A, ring finger protein 144A, UbcM4-interacting protein 4, Ubiquitin-conjugating enzyme 7-interacting protein 4

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P87632
Synonyms: RNF81, RO52, SSA1, TRIM21, E3 ubiquitin-protein ligase TRIM21, 52 kDa Ro protein, 52 kDa ribonucleoprotein autoantigen Ro/SS-A, ring finger protein 81, Ro(SS-A), Sjoegren syndrome type A antigen, Tripartite motif-containing protein 21, SS-A

Host:  

Mouse

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P71570
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Trim21; Ro52; Ssa1; E3 ubiquitin-protein ligase TRIM21; EC 2.3.2.27; 52kDa Ro protein; 52kDa ribonucleoprotein autoantigen Ro/SS-A; ring-type E3 ubiquitin transferase TRIM21; Ro(SS-A); Sjoegren syndrome type A antigen; SS-A; Tripartite motif-containing protein 21
Species:  
Source:  
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