20 Results for "

ADM

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "ADM" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N0876
CAS No.: 464-74-4
Arenobufagin is a natural bufadienolide that can be extracted from toad venom. Arenobufagin can induce apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Arenobufagin has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. Arenobufagin can inhibit VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway .
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1
1 Cited Publications
Cat. No.: HY-P74426
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Pro-adrenomedullin; ADM; Adrenomedullin; AM; PAMP
Species:  
Source:  
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Cat. No.: HY-P99177
CAS No.: 2305638-98-4

Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease Infection

Enibarcimab is a humanized, non-neutralizing monoclonal antibody targeting adrenomedullin (ADM). Enibarcimab binds to the N-terminus of ADM, retains ADM in the circulation, and mobilizes interstitial ADM to increase the level of active bio-ADM, ultimately stabilizing blood vessels. Enibarcimab can be used in research related to septic shock and acute heart failure .
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Cat. No.: HY-N1514
CAS No.: 100665-41-6
Ganoderenic acid B is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderenic acid B exhibits potent reversal effect on ABCB1-mediated multidrug resistance of HepG2/ADM cells to Doxorubicin .
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Cat. No.: HY-P1838
CAS No.: 166798-69-2
Research Areas:  

Cardiovascular Disease

Proadrenomedullin (45-92), human is a peptide corresponding to amino acids 45-92 of human preproadrenomedullin. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products .
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Cat. No.: HY-P3919
CAS No.: 166546-72-1
Synonyms: Pro-ADM-153-185 (human)
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

Adrenotensin (human) (Pro-ADM-153-185 (human)) is a 153-185 fragment of precursor peptide of Adrenomedullin. Adrenomedullin (ADM) is a 52-amino acid multifunctional peptide, which belongs to the CGRP superfamily of vasoactive peptide hormones .
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Cat. No.: HY-124277
CAS No.: 1644134-60-0
Target:  

TRP Channel

Research Areas:  

Neurological Disease

ADM 12 is a highly selective transient receptor potential ankyrin 1 (TRPA1) channel antagonist. ADM 12 blocks nitroglycerin (NTG)-induced trigeminal hyperalgesia in animal models, reducing expression of pain-related genes (c-Fos, TRPA1) and neuropeptides (CGRP, SP). ADM_12 is promising for research of migraine and neuropathic pain .
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Cat. No.: HY-P3919A
Synonyms: Pro-ADM-153-185 (human) TFA
Target:  

CGRP Receptor

Research Areas:  

Cardiovascular Disease

Adrenotensin (human) (Pro-ADM-153-185 (human)) TFA is a 153-185 fragment of precursor peptide of Adrenomedullin. Adrenomedullin (ADM) TFA is a 52-amino acid multifunctional peptide, which belongs to the CGRP superfamily of vasoactive peptide hormones .
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Cat. No.: HY-178349
Research Areas:  

Cancer

P-gp inhibitor 30 is a potent P-gp inhibitor that reverses multidrug resistance in breast cancer by sensitizing resistant cells to Doxorubicin (ADM) (HY-15142). P-gp inhibitor 30 promotes apoptosis, induces autophagy, and suppresses proliferation, migration, and invasion of drug-resistant breast cancer cells when combined with ADM. P-gp inhibitor 30 inhibits breast tumor growth both in vitro and in vivo. P-gp inhibitor 30 can be used for drug-resistant breast cancer research .
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Cat. No.: HY-RS00386
Research Areas:  

Others

ADM Human Pre-designed siRNA Set A contains three designed siRNAs for ADM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23391
Research Areas:  

Others

Adm Rat Pre-designed siRNA Set A contains three designed siRNAs for Adm gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00387
Research Areas:  

Others

ADM2 Human Pre-designed siRNA Set A contains three designed siRNAs for ADM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS00388
Research Areas:  

Others

ADM5 Human Pre-designed siRNA Set A contains three designed siRNAs for ADM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS20246
Research Areas:  

Others

Adm2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Adm2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26754
Research Areas:  

Others

Adm2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Adm2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N0876R
CAS No.: 464-74-4
Arenobufagin is a natural bufadienolide that can be extracted from toad venom. Arenobufagin can induce apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Arenobufagin has potent antineoplastic activity against HCC HepG2 cells as well as corresponding multidrug-resistant HepG2/ADM cells. Arenobufagin can inhibit VEGF-mediated angiogenesis through suppression of VEGFR-2 signaling pathway .
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Cat. No.: HY-RS16948
Research Areas:  

Others

Adm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Adm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P88258
Synonyms: AM; PAMP

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P88258A
Synonyms: AM; PAMP

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P73987
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HA; Hemagglutinin; HA/Hemagglutinin Protein, H5N1 (A/Cambodia/S1211394/2008, HEK293, His)
Species:  
Source:  
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