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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
ALK7
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "ALK7" in MCE Product Catalog:
316
316 Publications Verification
Target:
Research Areas:
SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways .
141
141 Cited Publications
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A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively .
141
141 Cited Publications
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Research Areas:
A 83-01 sodium is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively .
24
24 Cited Publications
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SB-505124 is a selective inhibitor of TGF-β Receptor type I receptors (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
24
24 Cited Publications
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SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
4
4 Cited Publications
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AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth .
Cat. No.: HY-10431R
CAS No.: 301836-41-9
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SB-431542 (Standard) is the analytical standard of SB-431542. SB-431542 is a TGF-β receptor kinase inhibitor (TRKI). SB-431542 has inhibitory activity for ALK4, ALK5 and ALK7 with IC50 values of 1 μM, 0.75 μM and 2 μM, respectively. SB-431542 also inhibits TGF-β-induced transcription, gene expression, apoptosis, and growth suppression. SB-431542 can be used for the research of cancer and signal transduction pathways .
Cat. No.: HY-10432R
CAS No.: 909910-43-6
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Research Areas:
A 83-01 (Standard) is the analytical standard of A 83-01 (HY-10432). This product is intended for research and analytical applications. A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively .
Cat. No.: HY-RS00242
Target:
Research Areas:
ACVR1C Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P992188
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Cat. No.: HY-13521AR
CAS No.: 356559-13-2
Target:
Research Areas:
SB-505124 (hydrochloride) (Standard) is the analytical standard of SB-505124 (hydrochloride). This product is intended for research and analytical applications. SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
Cat. No.: HY-13521R
CAS No.: 694433-59-5
Target:
Research Areas:
SB-505124 (Standard) is the analytical standard of SB-505124. This product is intended for research and analytical applications. SB-505124 is a selective inhibitor of TGF-β Receptor type I receptors (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
Cat. No.: HY-P704136
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7
Species:
Source:
Cat. No.: HY-P704137
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7
Cat. No.: HY-P704349
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7
Cat. No.: HY-P75573
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7
Species:
Source:
Cat. No.: HY-P704149
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Activin receptor type IC; ACTR-IC; ACVRLK7; ALK7
Cat. No.: HY-RS00244
Target:
Research Areas:
Acvr1c Rat Pre-designed siRNA Set A contains three designed siRNAs for Acvr1c gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00243
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Acvr1c Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acvr1c gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
