Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
ALX
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "ALX" in MCE Product Catalog:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-19574
CAS No.: 903895-98-7
Target:
Research Areas:
FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist .
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P7061A
Target:
Research Areas:
Cat. No.: HY-P99397
CAS No.: 1414386-05-2
Synonyms: ALX 0761; M 1095
Target:
Research Areas:
Cat. No.: HY-P99647
CAS No.: 1257358-38-5
Synonyms: ALX-0171; VR-465
Cat. No.: HY-P99385
CAS No.: 1628814-88-9
Synonyms: ALX-0061
Target:
Research Areas:
Cat. No.: HY-P99950
CAS No.: 2484949-51-9
Synonyms: ALX148
Target:
Research Areas:
ACT-389949 is a first-in-class, potent and selective and agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. ACT-389949 has potential for the treatment of inflammatory disorders .
Cat. No.: HY-W668775
CAS No.: 871100-12-8
Research Areas:
Quin-C7 is an orally active FPR2/ALX antagonist. Quin-C7 binds to the orthosteric ligand-binding pocket of FPR2/ALX, modulates receptor activation, and inhibits pro-inflammatory ERK signaling mediated by serum amyloid A (SAA). Quin-C7 reduces pro-inflammatory mediators TNF-α levels, increases anti-inflammatory IL-10, decreases inflammatory neutrophils and pro-inflammatory M1 macrophages, downregulates ERK1/2 phosphorylation, and upregulates JNK1/2/3 phosphorylation. Quin-C7 blocks FPR2/mFpr2 signaling, reduces brain lesion volume. Quin-C7 can be used for the research of inflammatory bowel disease and neuromyelitis optica spectrum disorder .
Synonyms: ALX-101
Target:
Research Areas:
Rovazolac is a liver x receptor (LXR) modulator extracted from patent WO2013130892A1.
Synonyms: (R)-NFPS hydrochloride
Target:
Research Areas:
ALX-5407 ((R)-NFPS) hydrochloride is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 hydrochloride can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia .
Cat. No.: HY-111029A
Purity: 99.83%
ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
Cat. No.: HY-113509B
CAS No.: 171030-11-8
Synonyms: 15-epi-LXA4
Category:
Target:
Cat. No.: HY-111029
CAS No.: 949164-09-4
Target:
Research Areas:
ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
Cat. No.: HY-P7061
CAS No.: 143413-49-4
Target:
Research Areas:
Cat. No.: HY-RS00636
Target:
Research Areas:
ALX1 Human Pre-designed siRNA Set A contains three designed siRNAs for ALX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1624S1
Synonyms: ALX-0600-Leu(13C6,15N) sodium
Research Areas:
Cat. No.: HY-P991647
Cat. No.: HY-10711
CAS No.: 571147-18-7
Synonyms: (R)-NFPS
Target:
Research Areas:
ALX-5407 ((R)-NFPS) is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
