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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
ARF
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "ARF" in MCE Product Catalog:
12
12 Publications Verification
Synonyms: NAV-2729
Grassofermata is a dual Arf1/Arf6 activation inhibitor. ADP ribosylation factors (Arfs) are members of the Arf family of GTP-binding proteins of the Ras superfamily.
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2 Cited Publications
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MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a Kd of 27.7 μM. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARF locus in prostate cancer cells .
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1 Cited Publications
Bragsin2 is a potent, selective and noncompetitive nucleotide exchange factor BRAG2 inhibitor, with an IC50 of 3 μM. Bragsin2 binds at the interface between the PH domain of BRAG2 and the lipid bilayer, leads BRAG2 unable to activate lipidated Arf GTPase. Bragsin2 affects breast cancer stem cells .
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1 Cited Publications
Cat. No.: HY-P80615
Synonyms: CDK4 inhibitor p16 INK4 antibody;
CDK4I antibody;
CDKN2 antibody;
CDKN2A antibody;
Cell cycle negative regulator beta antibody;
CMM2 antibody;
Cyclin dependent kinase 4 inhibitor A antibody;
Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody;
Cyclin Dependent Kinase Inhibitor 2A antibody;
Cyclin dependent kinase inhibitor 2A isoform 4 antibody;
Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody;
Cyclin dependent kinase inhibitor p16 antibody;
INK4 antibody;
INK4A antibody;
MLM antibody;
MTS1 antibody;
Multiple tumor suppressor 1 antibody;
p14 antibody;
p16 antibody;
P16INK4 antibody;
p16INK4a antibody;
p19 antibody;
p19ARF antibody;
TP16 antibody;
Cat. No.: HY-100767
CAS No.: 148892-91-5
Synonyms: Guanosine 5'-[β,γ-imido]triphosphate trisodium
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Bragsin1 is a potent, selective and noncompetitive inhibitor of the ArfGEF BRAG2, inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin1 binds to PH domain of BRAG2, and is a noncompetitive interfacial inhibitor. Bragsin1 has no effect on the Sec7 domain of human ArfGEFs. Anti-cancer activity .
Cat. No.: HY-P10553
CAS No.: 935732-44-8
Cat. No.: HY-RS00898
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ARF6 Human Pre-designed siRNA Set A contains three designed siRNAs for ARF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-151461
CAS No.: 2756173-91-6
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CHNQD-01255 is an orally active Arf-GEFs inhibitor with potent anti-hepatocellular carcinoma (HCC) efficacy .
Cat. No.: HY-P10553A
Cat. No.: HY-177269
CAS No.: 2648988-92-3
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CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research .
Cat. No.: HY-P10179
CAS No.: 1026775-53-0
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Cat. No.: HY-175290
CAS No.: 3091068-95-7
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Arf1-GEFs-IN-1 is a potent and orally active ADP-ribosylation factor 1- guanine nucleotide exchange factors (Arf1-GEFs) inhibitor with an IC50 value of 40.85 μM against CT26 cells. Arf1-GEFs-IN-1 primarily mediates tumor regression by triggering anti-tumor immune responses, rather than through direct cytotoxicity. Arf1-GEFs-IN-1 effectively promotes CCL5 expression, demonstrates excellent in vivo efficacy. Arf1-GEFs-IN-1 can be used for the study of colon cancer .
Cat. No.: HY-P10658
CAS No.: 143228-35-7
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Cat. No.: HY-P10157
CAS No.: 1027629-94-2
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Cat. No.: HY-P10178
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Cat. No.: HY-P10594
CAS No.: 143244-89-7
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Cat. No.: HY-RS00894
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ARF1 Human Pre-designed siRNA Set A contains three designed siRNAs for ARF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
