Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
ASH
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "ASH" in MCE Product Catalog:
7
Category:
Flavones Metabolic Disease Plants Brassicaceae Extract Phyllanthus Flavonoids Phenols Polyphenols Disease Research Fields Coronopus didymus Euphorbiaceae Extract
Target:
5
Category:
Monophenols Coumarins Phenols Phenylpropanoids Plants Other Families Extract Disease Research Fields Cancer
Target:
5
5 Cited Publications
Cat. No.: HY-W166297
CAS No.: 66778-17-4
Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway .
2
2 Cited Publications
Target:
연구분야:
AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
2
2 Cited Publications
Cat. No.: HY-141429
CAS No.: 2323623-93-2
Target:
연구분야:
AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
Cat. No.: HY-N6990
CAS No.: 29388-33-8
Category:
Lignans Phenols Polyphenols Phenylpropanoids Plants Other Families Extract Disease Research Fields Cancer
Target:
Target:
연구분야:
AS-85 is a potent ASH1L histone methyltransferase inhibitor (IC50=0.6 μM) with anti-leukemic activity. AS-85 strongly binds to the ASH1L SET domain, with the Kd value of 0.78 μM .
Synonyms: SEW04784
Target:
연구분야:
SEW84 is an inhibitor of Aha1-stimulated Hsp90 (ASH) ATPase activity. SEW84 inhibits Aha1-stimulated Hsp90 (ASH) activity with an IC50 value of 0.3 μM. SEW84 can be used in the study of protein deposition diseases .
Cat. No.: HY-121471R
CAS No.: 491-71-4
Cat. No.: HY-170494
CAS No.: 3096805-79-4
Target:
연구분야:
AS-254s is the inhibitor for absent, small, or homeotic-like 1 protein (ASH1L) with an IC50 of 94 nM (FP assay). AS-254s exhibits antiproliferative activity against MLL1-rearranged leukemic cells with GI50 <1 μM. AS-254s induces the differentiation of MLL1-r leukemic cell .
Cat. No.: HY-W111589F
CAS No.: 68855-54-9
Cat. No.: HY-RS16309
Target:
연구분야:
Rab27a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rab27a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Target:
Cat. No.: HY-16521
CAS No.: 800408-39-3
Target:
연구분야:
VX-166, a pan caspase inhibitor, can be used for the research of Non- Alcoholic Fatty Liver Disease (NAFLD), nonalcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), and other diseases involving fibrosis, steatosis, or inflammation of the liver .
Cat. No.: HY-141429C
Target:
연구분야:
AS-99 is a first-in-class, potent, and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, downregulates MLL fusion target genes, and reduces the leukemia burden in vivo .
Cat. No.: HY-RS01087
Target:
연구분야:
ASH1L Human Pre-designed siRNA Set A contains three designed siRNAs for ASH1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01088
Target:
연구분야:
ASH2L Human Pre-designed siRNA Set A contains three designed siRNAs for ASH2L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24225
Target:
연구분야:
Ash1l Rat Pre-designed siRNA Set A contains three designed siRNAs for Ash1l gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17407
Target:
연구분야:
Grb2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Grb2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
