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Results for "

Aggregation-induced emission

" in MedChemExpress (MCE) Product Catalog:

23

Inhibitors & Agonists

10

Fluorescent Dye

1

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118159
    Diphenyl-1-pyrenylphosphine

    DPPP

    		 Fluorescent Dye Others
    Diphenyl-1-pyrenylphosphine (DPPP) is a functional organic molecule with both fluorescent properties and metal coordination ability, which is commonly used in materials and coordination chemistry research. Upon exposure to ultraviolet light, Diphenyl-1-pyrenylphosphine undergoes photoinduced phosphorus atom oxidation to form O-DPPP, triggering a transition from aggregation-induced emission (AIE) to aggregation-caused quenching (ACQ). Diphenyl-1-pyrenylphosphine reacts stoichiometrically with lipid hydroperoxides to produce fluorescent diphenyl-1-pyrenylphosphine oxide. Diphenyl-1-pyrenylphosphine can insert into cell membranes to monitor lipid peroxidation processes in living cells .
    Diphenyl-1-pyrenylphosphine
  • HY-152073
    BETA-1

    		Fluorescent Dye Others
    BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. BETA-1 emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. BETA-1 can be used for the simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro .
    BETA-1
  • HY-D1456
    TEPC466

    		Pyruvate Kinase Cancer
    TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .
    TEPC466
  • HY-W008048
    2',3'-O-Isopropylideneadenosine

    		Nucleoside Antimetabolite/Analog Others
    2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
    2',3'-O-Isopropylideneadenosine
  • HY-W856375A
    BSPOTPE

    		Fluorescent Dye Others
    BSPOTPE is the mixture of (E)-BSPOTPE (HY-W856375) and (Z)-BSPOTPE. BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
    BSPOTPE
  • HY-D1504
    IR-797 chloride

    		Fluorescent Dye Others
    IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic .
    IR-797 chloride
  • HY-D2268
    QM-FN-SO3

    		Fluorescent Dye Amyloid-β Neurological Disease
    QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
    QM-FN-SO3
  • HY-W856375
    (E)-BSPOTPE

    		MOFs Fluorescent Dye Others
    (E)-BSPOTPE is the E configuration of BSPOTPE (HY-W856375A). BSPOTPE binds Human serum albumin (HSA) (HY-P1956), exhibits aggregation-induced emission (AIE) phenomenon. BSPOTPE shows selectivity for albumin (such as HSA and BSA), but has no obvious fluorescence response to other proteins and DNA. BSPOTPE can be used as fluorescent probe for HSA .
    (E)-BSPOTPE
  • HY-D1468
    Phototherapeutic agent-1

    		Reactive Oxygen Species (ROS) Cancer
    Phototherapeutic agent-1 is a multi-modal light diagnosis agent with aggregation-induced emission properties. have certain Phototherapeutic agent-1 has certain reactive oxygen species (ROS) generation capacity in illumination condition. Phototherapeutic agent-1 can effectively kill cancer cells and tumor tissue .
    Phototherapeutic agent-1
  • HY-151468
    AIE-Cbz-LD-C7

    		Fluorescent Dye Others
    AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER) .
    AIE-Cbz-LD-C7
  • HY-139673
    BG dimer

    		Fluorescent Dye Others
    BG dimer is a molecular dimer organic luminogen with aggregation-induced emission.
    BG dimer
  • HY-145241
    TBTDC

    		Photosensitizer Neurological Disease
    TBTDC is a highly efficient multifunctional organic photosensitizer with aggregation-induced emission for in vivo bioimaging and photodynamic research.
    TBTDC
  • HY-151536
    meso-Benzothiazole-BODIPY 505/515

    		Fluorescent Dye Neurological Disease
    meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeaggregation-induced emission (AIE) properties. meso-Benzothiazole-BODIPY 505/515 can monitor cellular viscosity changes and autophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases .
    meso-Benzothiazole-BODIPY 505/515
  • HY-D2268A
    QM-FN-SO3 ammonium

    		Amyloid-β Fluorescent Dye Neurological Disease
    QM-FN-SO3 ammonium is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE)-active probe for Aβ plaques. QM-FN-SO3 ammonium can be used for in vivo detection of Aβ plaques. QM-FN-SO3 ammonium has ultra-high S/N ratio, binding affinity, and high-performance NIR emission .
    QM-FN-SO3 ammonium
  • HY-170490
    TTQ-SA

    		Photosensitizer Apoptosis Cancer
    TTQ-SA is a near-infrared (NIR) spiro-AIEgen (aggregation-induced emission luminogen), that converts near-infrared light (NIR) into thermal energy, causing thermal damage and death of tumor cells. TTQ-SA exhibits cellular uptake and targeting ability in cancer cell MF-7. TTQ-SA silences the expression of survivin gene with combination of DNAzyme, enhances the sensitivity of tumor cells to photothermal therapy .
    TTQ-SA
  • HY-D2639
    TPE-PY

    		Fluorescent Dye Metabolic Disease
    TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria .
    TPE-PY
  • HY-W008048S
    2',3'-O-Isopropylideneadenosine-13C5

    		Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog Others
    2',3'-O-Isopropylideneadenosine- 13C5 is the 13C-labeled 2',3'-O-Isopropylideneadenosine (HY-W008048). 2',3'-O-Isopropylideneadenosine is a nucleoside compound and also a Golgi-targeting moiety. 2',3'-O-Isopropylideneadenosine constitutes a furanose ribose group that undergoes cyclization at the O (2') and O (3') atoms. As a component of the fluorescent probe TPE-Ade, 2',3'-O-Isopropylideneadenosine enables specific Golgi localization for fluorescence imaging. 2',3'-O-Isopropylideneadenosine participates in the synthesis of aggregation-induced emission (AIE) fluorescent probes .
    2',3'-O-Isopropylideneadenosine-13C5
  • HY-183797
    Antitumor agent-218

    		Cancer
    Antitumor agent-218 is an aggregation-induced emission (AIE)-based photosensitizer. Antitumor agent-218 selectively accumulates in the endoplasmic reticulum, and generates ROS within the endoplasmic reticulum upon irradiation to induce necroptosis of tumor cells. Antitumor agent-218 can be used in cancer-related research .
    Antitumor agent-218
  • HY-163034
    Antitumor photosensitizer-5

    		Apoptosis Reactive Oxygen Species (ROS) Cancer
    Antitumor photosensitizer-5 (Ru2) is a photosensitizer which effectively target tumor mitochondria with an IC50 of 0.3 μM for phototoxicity to A549 cells. Under 460 nm light irradiation, antitumor photosensitizer-5 induces the generation of reactive oxygen species and NADH depletion, causes mitochondrial damage and activation of caspase-3, inducing apoptosis and suppressing cell migration. Antitumor photosensitizer-5 has the potential to prevent the growth of malignant tumors, therefore, shows the potential to be applied to photodynamic therapy .
    Antitumor photosensitizer-5
  • HY-D3227
    HOTN

    		Fluorescent Dye Inflammation/Immunology Cancer
    HOTN is a hypochlorous acid (HClO) Fluorescent indicator. HOTN is oxidized by HClO, causing cleavage of its Py +-N + moiety and a change in hydrophobicity, which in turn triggers aggregation-induced emission to generate a strong fluorescent signal. HOTN is used for in vivo imaging of inflammation and hepatocellular carcinoma, as these diseases typically result in high levels of HClO .
    HOTN
  • HY-175163
    TPAPyN

    		Photosensitizer Cancer
    TPAPyN is a nitroreductase(NTR)-responsive type I photosensitizer. TPAPyN facilitates the imaging of hypoxic cancer cells and image-guided photodynamic therapy (PDT). TPAPyN does not emit fluorescence in the aqueous environment, but restores when NTR cleaves the nitrofuran quencher with aggregation-induced emission. TPAPyN can be used as a fluorescent probe for specific imaging of hypoxic cancer .
    TPAPyN
  • HY-W075283
    4-(1,2,2-Triphenylvinyl)aniline

    1-(4-Aminophenyl)-1,2,2-triphenylethene

    		 Others
    4-(1,2,2-Triphenylvinyl)aniline (1-(4-Aminophenyl)-1,2,2-triphenylethene) is a tetraphenylethene-based aggregation-induced luminescent molecule. 4-(1,2,2-Triphenylvinyl)aniline exhibits weak or no fluorescence in dilute solution/dispersed state, and strong fluorescence with increased quantum yield when aggregated into nanoparticles .
    4-(1,2,2-Triphenylvinyl)aniline
  • HY-D3143
    QM-B-CF

    		Fluorescent Dye Cancer
    QM-B-CF is a sequential dual-lock chemiluminescent/fluorescent dual-mode probe designed for the specific detection of H2O2, and it can produce enhanced chemiluminescence upon photoirradiation. QM-B-CF generates chemiluminescent signals only under the conditions of H2O2 and light exposure in vitro, in cancer cells, and in tumor-bearing nude mice (Ex/Em = 514 nm/600 nm) .
    QM-B-CF

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