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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1674 Results for "
Bis
" in MedChemExpress (MCE) Product Catalog:
Products (1674)
1674 Results for "Bis" in MCE Product Catalog:
20
20 Publications Verification
Synonyms: NSC-77037; d-Tetrandrine
Category:
Stephania tetrandra S. Moore Alkaloids Plants Disease Research Fields Inflammation/Immunology Menispermaceae Alkaloid Dimers
Target:
14
14 Cited Publications
Synonyms: Couroupitine B; Indigo red; Indigopurpurin
Target:
13
13 Cited Publications
Synonyms: Bis(2-ethylhexyl) phthalate; Ergoplast FDO; ESBO-D 82
12
12 Cited Publications
Synonyms: Bis(POC)-PMPA; GS 4331
Target:
Research Areas:
Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
12
12 Cited Publications
Synonyms: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate
Target:
Research Areas:
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
6
6 Cited Publications
Synonyms: Methylglyoxal-Bis(guanylhydrazone); MGBG; Methyl-GAG
Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment .
5
Category:
Alkaloids other families Phenols Polyphenols Plants Disease Research Fields Isoquinoline Alkaloids Cancer
Target:
4
4
4 Cited Publications
Target:
Research Areas:
RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.
3
3 Cited Publications
Synonyms: 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride
Target:
Research Areas:
AHN 1-055 hydrochloride is a dopamine uptake inhibitor that can cross the blood-brain barrier, with an IC50 of 71 nM. AHN 1-055 hydrochloride binds with high affinity to the dopamine transporter (DAT) .
3
3 Cited Publications
Synonyms: 2′,7′-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein
2
Research Areas:
Bis(4-nitrophenyl) phosphate (BNPP) is an esterase inhibitor, inhibits the activity of esterases such as carboxylesterase. Bis(4-nitrophenyl) phosphate inhibits the degradation of Abiraterone in fresh plasma. Bis(4-nitrophenyl) phosphate can be used as a substrate to determine the enzymatic activity of phosphodiesterase in the roots of wetland plants. Bis(4-nitrophenyl) phosphate also acts as a catalyst for metallomicelles and a catalyst that promotes ring-opening polymerization (ROP) .
2
2
2 Cited Publications
Synonyms: DSSeb; Sebacic acid Bis N-succinimidyl ester
Target:
Research Areas:
Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides .
2
2 Cited Publications
Synonyms: 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide
Target:
Research Areas:
HC-056456 is an effective but not perfectly-selective blocker of CatSper channels. The [Na +]i rise is slowed by HC-056456 (IC50~3 µM).
1
1
1 Cited Publications
Target:
Research Areas:
Bis-PEG2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC).
1
1 Cited Publications
Synonyms: Bis(2-ethylhexyl) phthalate (Standard); Ergoplast FDO (Standard); ESBO-D 82 (Standard)
Category:
1
Category:
Target:
1
1 Cited Publications
Synonyms: Ro 31-7549 acetate; Bis VIII acetate
Research Areas:
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively . Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
