42 Results for "

C1q

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "C1q" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
5
5 Cited Publications
Cat. No.: HY-P990545
CAS No.: 2065212-40-8
Synonyms: ANX005

Target:  

Complement System

Research Areas:  

Neurological Disease

Tanruprubart (ANX005) is a C1q inhibitor and C1q depleter. Tanruprubart is a human antibody expressed in CHO cells, with huIgG1 heavy chains and huκ light chains, and its predicted molecular weight (MW) is 145 kDa. For the isotype control of Tanruprubart, refer to Human IgG4 kappa, Isotype Control (HY-P99003). The IC50 of Tanruprubart is 346 ng/mL for humans and 259 ng/mL for rats; its EC50 is 3.8 ng/mL for humans, 5.2 ng/mL for rats, and 9.9 ng/mL for mice. Tanruprubart is applicable to the research of Guillain-Barré syndrome and Alzheimer's disease [1].
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2
2 Cited Publications
Cat. No.: HY-P7461
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P75464
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1qB; Complement Subcomponent C1q Chain B; Complement C1q B Chain; Complement C1q Chain B; Complement Component 1, Q Subcomponent, Beta Polypeptide; Complement Component C1q, B Chain; Complement Component 1, Q Subcomponent, B Chain; C1qD2; Complement C1q
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-P71718
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1qA; Complement Component 1, Q Subcomponent, A Chain; Complement C1q A Chain; Complement C1q Chain A; Complement C1q Subcomponent Subunit A; Complement Component C1q, A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; C1qD1
Species:  
Mouse
Source:  
P. pastoris
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1
1 Cited Publications
Cat. No.: HY-P7127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7129
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P70504
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7358
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOQ; Adipocyte, C1q And Collagen Domain Containing; Prev. ACDC; Adipose Specific Collagen-Like Factor; Adiponectin; Gelatin-Binding Protein 28; ACRP30; Gelatin-Binding Protein; GBP28; Adiponectin Precursor; ApM1; ADIPQTL1; Adipose Most Abundant Gene Tr
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-NP0194A
C1q Protein (mouse) is a complement protein and is a recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. C1q Protein (mouse) binds various ligands derived from self, non-self, and altered self and modulate the functions of immune
and non-immune cells. C1q Protein (mouse) can be used for the research of mutiple disease [1].
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Cat. No.: HY-NP0194C
C1q Protein (rat) is a complement protein and is a recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. C1q Protein (rat) binds various ligands derived from self, non-self, and altered self and modulate the functions of immune
and non-immune cells. C1q Protein (rat) can be used for the research of mutiple disease [1].
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Cat. No.: HY-112307A
CAS No.: 124011-52-5
Purity:  99.97%
Target:  

Liposome

(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be studied for drug delivery and the synthesis of liposomes. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-containing liposomes can induce Tregs that are specific for the liposomes’ cargo. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is taken up by antigen-presenting cells mediated via complement component 1q (C1q) [1].
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Cat. No.: HY-P991055
CAS No.: 2649379-96-2
Synonyms: RG-6234; RO-7425781

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001) [1].
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Cat. No.: HY-P10827
CAS No.: 1356469-36-7
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM [1].
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Cat. No.: HY-NP0194B
C1q Protein (rabbit) is a complement protein and is a recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. C1q Protein (rabbit) binds various ligands derived from self, non-self, and altered self and modulate the functions of immune
and non-immune cells. C1q Protein (rabbit) can be used for the research of mutiple disease [1].
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Cat. No.: HY-P991886
Target:  

Complement System

Research Areas:  

Neurological Disease

ANX-M1 is a blood-brain barrier-permeable anti-C1q antibody. ANX-M1 can slow down the progression of retinal degeneration following photo-oxidative damage. ANX-M1 has been incorporated into nanocarriers to evaluate its brain delivery efficacy in a mouse model of Alzheimer's disease. ANX-M1 is applicable for research on age-related macular degeneration and Alzheimer's disease [1] .
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Cat. No.: HY-P992142
CAS No.: 3050549-24-8
Synonyms: ANX-007

Target:  

Complement System

Vonaprument (ANX-007) is an intravitreally injected C1q antibody fragment (with a molecular weight of approximately 48 kDa) and a human monoclonal antibody. Vonaprument inhibits the activation of the classical complement cascade by specifically recognizing the globular head of C1q and blocking substrate binding. After intravitreal injection, Vonaprument distributes to the retina, choroid and optic nerve, and achieves complete C1q target binding in the aqueous humor and retinal tissues. Vonaprument can be used in research related to neurodegenerative eye diseases such as age-related macular degeneration and glaucoma [1] .
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Cat. No.: HY-P992512
Target:  

Complement System

Research Areas:  

Neurological Disease

ANX-M1 Mouse IgG1 is a brain-penetrant C1q inhibitor. ANX-M1 Mouse IgG1 blocks classical complement pathway activation, reduces C1q concentrations in brain and plasma, and inhibits microglia-mediated synapse engulfment. ANX-M1 Mouse IgG1 can be used for the research of Huntington's disease, Alzheimer's disease, retinopathy and neuropathic pain [1] .
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Cat. No.: HY-184031
CAS No.: 133-65-3
Synonyms: Solapsone; Sulfetrone
Research Areas:  

Cancer

Solasulfone (Solapsone; Sulfetrone) is an inhibitor of complement protein C1q and β-lactamase. Solasulfone also acts as a chemotherapeutic agent and can be used in cancer research [1].
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Cat. No.: HY-P72108
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1qA; Complement Component 1, Q Subcomponent, A Chain; Complement C1q A Chain; Complement C1q Chain A; Complement C1q Subcomponent Subunit A; Complement Component C1q, A Chain; Complement Component 1, Q Subcomponent, Alpha Polypeptide; C1qD1
Species:  
Mouse
Source:  
E. coli
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Cat. No.: HY-P71639
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C1qTNF3; C1q And Tumor Necrosis Factor Related Protein 3; C1q And TNF Related 3; Secretory Protein CORS26; CTRP3; 2310005P21Rik; Cors-26; Cartonectin; Corcs; CORS26; Cors; Collagenous Repeat-Containing Sequence Of 26-KDa; Complement C1q Tumor Necrosis Fac
Species:  
Mouse
Source:  
E. coli
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