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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
CAMKK2
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "CAMKK2" in MCE Product Catalog:
8
8 Publications Verification
Cat. No.: HY-19870C
CAS No.: 2759937-80-7
Synonyms: RM-493 monoacetate; BIM-22493 monoacetate; IRC-022493 monoacetate
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
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1 Cited Publications
Cat. No.: HY-162009
CAS No.: 3032691-65-6
Target:
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CaMKK2-IN-1 is a selective, ligand-efficient inhibitor of CaMKK2, with IC50 of 7 nM .
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CZC-25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 can increase normal α-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 can be used to research Parkinson's disease and liver diseases [2] .
Cat. No.: HY-168905
CAS No.: 2561494-76-4
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Research Areas:
SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC50 of 1.6 μM .
Cat. No.: HY-RS01866
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Research Areas:
CAMKK2 Human Pre-designed siRNA Set A contains three designed siRNAs for CAMKK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-163064
CAS No.: 2922675-91-8
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CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with the IC50 of 9 nM .
Cat. No.: HY-E70813
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Research Areas:
CaMKK2 is a serine/threonine protein kinase and the central component of a Ca 2+-calmodulin activated signalling pathway. CaMKK2 is highly enriched in brain neurons and regulates energy metabolism and neuronal processes. CAMKK2 Recombinant Human Active Protein Kinase is obtained by expressing CAMKK2 proteins .
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SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8 .
Cat. No.: HY-RS17176
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Research Areas:
Camkk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Camkk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23626
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Camkk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Camkk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W017212R
CAS No.: 103-26-4
Synonyms: Methyl 3-phenylpropenoate (Standard)
Target:
Cat. No.: HY-117356A
CAS No.: 911391-37-2
MRS2693 ammonium is a selective P2Y6 receptor agonist. MRS2693 ammonium exerts biological effects by activating the Gq-coupled P2Y6 receptor, the ERK1/2 pathway, and the P2RY6-PLCB3-CAMKK2-PRKAA1-ULK1 signaling cascade. MRS2693 ammonium attenuates TNFα-induced NF-κB activation, stabilizes XIAP via AKT-mediated phosphorylation, induces autophagy, and reactivates PRKAA1. MRS2693 ammonium can be used in research on diseases including skeletal muscle ischemia/reperfusion injury, TNFα-induced skeletal muscle apoptosis, chronic myelomonocytic leukemia, colorectal cancer, and dry eye disease [2] .
Cat. No.: HY-15800
CAS No.: 1330003-04-7
Research Areas:
CZC-25146 hydrochloride is a potent LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 hydrochloride inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 hydrochloride prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 hydrochloride exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 hydrochloride can increase normal α-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 hydrochloride can be used to research Parkinson's disease and liver diseases [2] .
Cat. No.: HY-W017212S
CAS No.: 1219806-38-8
Synonyms: Methyl 3-phenylpropenoate-d7
Cat. No.: HY-P81205
Synonyms: Calcium/calmodulin dependent protein kinase beta; Calcium/calmodulin dependent protein kinase kinase 2; Calcium/calmodulin dependent protein kinase kinase beta; CaM kinase kinase beta; CaM KK beta; CAMKK 2; CAMKK; CAMKK beta; CAMKK beta protein; CAMKKB.
Cat. No.: HY-P706023
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase kinase beta; CAMKK beta; CAMKKB; KIAA0787
Species:
Source:
Cat. No.: HY-P88028
Synonyms: CAMKKB, KIAA0787, CAMKK2, Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CAMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CAMKK beta
Cat. No.: HY-N8016S2
CAS No.: 1335435-50-1
Cat. No.: HY-108458R
CAS No.: 459429-39-1
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Research Areas:
SB 452533 (Standard) is the analytical standard of SB 452533 (HY-108458). This product is intended for research and analytical applications. SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
