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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
CD30
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "CD30" in MCE Product Catalog:
2
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P99107A
CAS No.: 914088-09-8
Research Areas:
Brentuximab vedotin (solution) (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). The antibody portion is Brentuximab (HY-P99151), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Brentuximab vedotin (solution) inhibits CD30-positive cells with an IC50 of 2.5 ng/mL. Brentuximab vedotin (solution) can be used for the research of relapsed and refractory Hodgkin lymphoma .
1
1 Cited Publications
Cat. No.: HY-P70023
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuTumor necrosis factor receptor superfamily member 8/CD30, His; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8
Cat. No.: HY-P990710
CAS No.: 2738880-26-5
Synonyms: AFM13
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Cat. No.: HY-P99669
CAS No.: 640735-09-7
Synonyms: MDX-060
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Research Areas:
Cat. No.: HY-160649
CAS No.: 1599439-52-7
Research Areas:
MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC50 of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo .
Cat. No.: HY-P991638
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Cat. No.: HY-P991553
Target:
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Cat. No.: HY-P991512
Cat. No.: HY-177823
Target:
Research Areas:
C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells.
Cat. No.: HY-180412
CAS No.: 226072-63-5
Synonyms: BB-3644
Solimastat (BB-3644) is a potent metalloproteinase (MMP) inhibitor that blocks constitutive and antibody-stimulated CD30 shedding from cell surfaces with an IC50 of 180 nM. Solimastat enhances persistence of anti-CD30 antibody Ki-3 on cells and favors its internalization. Solimastat enhances cytotoxic activity of Ki-3.dgA towards CD30 + L540 cells. Solimastat can be used for the research of CD30 + malignancies .
Cat. No.: HY-P992404
Target:
Research Areas:
Cat. No.: HY-P700433
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuTumor necrosis factor receptor superfamily member 8/CD30, His; Tumor necrosis factor receptor superfamily member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD30; TNFRSF8
Cat. No.: HY-P705115
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; TNFRSF8
Cat. No.: HY-P701265
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF8; CD30; D1S166E; Ki-1
Cat. No.: HY-P700673
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD30; CD30KI-1; CD30L receptor; TNFRSF8; D1S166EKi-1; CD30KI-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
