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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
CP10
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "CP10" in MCE Product Catalog:
1
1 Cited Publications
CP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6 .
4
4 Cited Publications
Cat. No.: HY-P71275
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Rat
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P71076
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprotectin L1L Subunit; MA387; Cystic Fibrosis Antigen; L1Ag; S100-A8; NIF; 60B8AG; S100 Calcium Binding Protein A8; CGLA; S100A9; 60B8AG; Prev. CAGB; CGLB; Prev. CFAG; MIF; MRP-14; NIF; MRP14; Protein S100-A9; P14; Calgranulin B; Migration Inhibitory Factor-Related Protein 14; S100 Calcium-Binding Protein A9 (Calgranulin B); Leukocyte L1 Complex Heavy Chain; S100 Calcium-Binding Protein A9; Calprotectin L1H Subunit; Calgranulin-B; S100-A9; L1AG; MAC387; S100 Calcium Binding Protein A9; LIAG
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73671
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Mouse
Source:
Sf9 insect cells
Synonyms: PROTAC CDK6 ligand 1
Research Areas:
Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6 . Palbociclib-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Synonyms: Cereblon Ligand-Linker Conjugates 13; E3 ligase Ligand-Linker Conjugates 50
Research Areas:
Pomalidomide-PEG1-C2-N3 (Cereblon Ligand-Linker Conjugates 13) is a cereblon E3 ligand-linker conjugate that can be used to synthesisi selective CDK6 PROTAC degrader CP-10 (HY-125835). Pomalidomide-PEG1-C2-N3 can be used for the research of cancers .
Cat. No.: HY-RS12385
Target:
Research Areas:
S100A8 Human Pre-designed siRNA Set A contains three designed siRNAs for S100A8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71779
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Mouse
Source:
P. pastoris
Cat. No.: HY-P70531A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Human
Source:
E. coli
Cat. No.: HY-P76586
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705438
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: S100A8; MRP-8; Prev. CAGA; Urinary Stone Protein Band A; Prev. CFAG; Protein S100-A8; MRP8; Calgranulin A; P8; S100 Calcium-Binding Protein A8; Migration Inhibitory Factor-Related Protein 8; Calgranulin-A; Leukocyte L1 Complex Light Chain; CP-10; Calprote
Species:
Mouse
Source:
E. coli
Cat. No.: HY-RS16593
Target:
Research Areas:
S100a8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for S100a8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF9; CDw137; Prev. ILA; Tumor Necrosis Factor Receptor Superfamily, Member 9; CD137; Induced By Lymphocyte Activation (ILA); 4-1BB; Homolog Of Mouse 4-1BB; Tumor Necrosis Factor Receptor Superfamily Member 9; Receptor Protein 4-1BB; T-Cell Antigen 4-1
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
