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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
CTCL
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "CTCL" in MCE Product Catalog:
1
Target:
Áreas de investigación:
Target:
Áreas de investigación:
KT-333 is a molecular glues that degrades STAT3 protein. KT-333 mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) .
Referencia número: HY-P11107
No. CAS: 2375823-45-1
Target:
Áreas de investigación:
Referencia número: HY-156730A
No. CAS: 2839758-34-6
Target:
Áreas de investigación:
KT-333 ammonium (Compound A) is a molecular glues that degrades STAT3 protein. KT-333 ammonium mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 ammonium has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 ammonium can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) .
Referencia número: HY-156730B
No. CAS: 2502186-80-1
Target:
Áreas de investigación:
KT-333 diammonium is a molecular glues that degrades STAT3 protein. KT-333 diammonium mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 diammonium has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 diammonium can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) .
Referencia número: HY-RS15182
Target:
Áreas de investigación:
TSPYL2 Human Pre-designed siRNA Set A contains three designed siRNAs for TSPYL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-187609
No. CAS: 166981-11-9
CT 2576 is a phospholipid signaling inhibitor as well as a Jak3/STAT5 inhibitor. CT 2576 suppresses gene expression and replication of human immunodeficiency virus (HIV) at the post-transcriptional level by interfering with phospholipid metabolism in host cells, particularly by inhibiting the production of phosphatidic acid PA. CT-2576 completely inhibits the growth and proliferation of malignant T-cell lymphoma cells by suppressing phospholipid signaling and blocking the Jak/STAT signaling pathway associated with IL-2R. CT 2576 can be used in research related to human immunodeficiency virus (HIV) infection and cutaneous T-cell lymphoma (CTCL) .
Referencia número: HY-156730R
No. CAS: 2502186-79-8
Target:
Áreas de investigación:
KT-333 (Standard) is the analytical standard of KT-333 (HY-156730). This product is intended for research and analytical applications. KT-333 is a molecular glues that degrades STAT3 protein. KT-333 mediates the selective degradation of STAT3 through the ubiquitin-proteasome system by binding to STAT3 protein and E3 ubiquitin ligase von Hippel-Lindau protein (VHL). KT-333 has strong selectivity for STAT3 protein degradation and good antitumor activity. KT-333 can be used in the study of hematologic malignancies such as large granular lymphocytic leukemia (LGL-L), peripheral T-cell lymphoma (PTCL), and cutaneous T-cell lymphoma (CTCL) .
Referencia número: HY-P75521
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AKR1B1; ALR2; Prev. ALDR1; Lii5-2 CTCL Tumor Antigen; Aldose Reductase; Low Km Aldose Reductase; AR; Aldehyde Reductase 1; Aldo-Keto Reductase Family 1 Member B1; ADR; Aldehyde Reductase; Aldo-Keto Reductase Family 1 Member B; Aldo-Keto Reductase Family 1
Species:
Human
Source:
E. coli
Referencia número: HY-P77222
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TAOK3; CTCL-Associated Antigen HD-CL-09; TAO Kinase 3; Kinase From Chicken Homolog A; MAP3K18; Jun Kinase-Inhibitory Kinase; JIK; JNK/SAPK-Inhibitory Kinase; DPK; HKFC-A; Thousand And One Amino Acid Protein 3; Non-Specific Serine/Threonine Protein Kinase
Species:
Human
Source:
Sf9 insect cells
Referencia número: HY-P703907
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TAOK3; CTCL-Associated Antigen HD-CL-09; TAO Kinase 3; Kinase From Chicken Homolog A; MAP3K18; Jun Kinase-Inhibitory Kinase; JIK; JNK/SAPK-Inhibitory Kinase; DPK; HKFC-A; Thousand And One Amino Acid Protein 3; Non-Specific Serine/Threonine Protein Kinase
Species:
Human
Source:
Sf9 insect cells
Referencia número: HY-P85558
Synonyms: ADR; AKR1B 1; Akr1b1; Aldehyde reductase 1; Aldehyde reductase; Aldo keto reductase family 1, member B1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1; aldose reductase; Aldose reductase; aldr 1; ALDR_HUMAN; ALDR1; ALR2; AR; Lii5 2 CTCL tumor antigen; Low Km aldose reductase; MGC1804.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
