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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
CXCL11
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "CXCL11" in MCE Product Catalog:
40
40 Publications Verification
Target:
Research Areas:
AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively .
9
9 Cited Publications
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Research Areas:
NBI-74330 is a potent antagonist for CXCR3, and exhibits potent inhibition of ( 125I)CXCL10 and ( 125I)CXCL11 specific binding with Ki of 1.5 and 3.2 nM, respectively.
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2 Cited Publications
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Research Areas:
CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases .
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2 Cited Publications
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Research Areas:
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases .
1
1 Cited Publications
Cat. No.: HY-P700169AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL11; Scyb11C-X-C motif chemokine 11; Interferon-inducible T-cell alpha chemoattractant; I-TAC; Small-inducible cytokine B11
1
1
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ACT-777991 is an orally active and selective CXCR3 antagonist. ACT-777991 has microsomes and hepatocytes stability across animal models. ACT-777991 inhibits the migration of activated T cells toward CXCL11 .
Cat. No.: HY-165428
CAS No.: 907206-98-8
Research Areas:
SCH-900875 is an orally active, brain-penetrant and selective CXCR3 receptor inhibitor, which also shows high selectivity over CXCR1 and CXCR2 receptors. SCH-900875 binds to CXCR3, blocking the binding of ligands CXCL9, CXCL10, and CXCL11, inhibiting downstream G protein and β-arrestin signaling pathways to suppress inflammatory cell migration. SCH-900875 is promising for research of autoimmune diseases (rheumatoid arthritis, multiple sclerosis) and inflammatory disorders (psoriasis, inflammatory bowel disease) .
Cat. No.: HY-RS03385
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Research Areas:
CXCL11 Human Pre-designed siRNA Set A contains three designed siRNAs for CXCL11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23142
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Research Areas:
Cxcl11 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cxcl11 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W505771
CAS No.: 523-59-1
Category:
Flavonoids Ficus erecta Thunb. var. beecheyana (Hook.et Arn.) King Plants Moraceae Other Flavonoids
Target:
Cat. No.: HY-RS16707
Target:
Research Areas:
Cxcl11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cxcl11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-15319A
CAS No.: 947536-03-0
(±)-AMG 487 is a racemate of AMG 487. AMG 487 is an orally active and selective antagonist of CXC chemokine receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively .
Cat. No.: HY-167884
CAS No.: 319461-60-4
Target:
Cat. No.: HY-113730
CAS No.: 860002-95-5
VUF5834 is a non-peptide chemokine receptor CXCR3 antagonist with non-competitive antagonistic and inverse agonistic activities. VUF5834 blocks the effects of CXCL10 and CXCL11 on human CXCR3, exhibits non-competitive antagonistic and inverse agonistic properties to CXCR3, and, except for TAK-779, has a slightly lower affinity for rodent CXCR3 than for primate CXCR3.
Cat. No.: HY-P700042AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: I-TAC/CXCL11; C-X-C motif chemokine 11; Beta-R1; H174; IP-9; SCYB11
Cat. No.: HY-P700233AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-X-C motif chemokine 11; Beta-R1; H174; IP-9; SCYB11
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
