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Cosmetics

" in MedChemExpress (MCE) Product Catalog:

506

Inhibitors & Agonists

4

Screening Libraries

56

Fluorescent Dye

135

Biochemical Assay Reagents

107

Peptides

122

Natural
Products

41

Isotope-Labeled Compounds

18

Oligonucleotides

Cat. No. Product Name Target Research Area
  • HY-P0063
    Copper tripeptide
    1 Publications Verification

    GHK-Cu

    		 Biochemical Assay Reagents Inflammation/Immunology
    Copper tripeptide (GHK-Cu) is a tripeptide. During wound healing, Copper tripeptide may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide is a natural modulator of multiple cllular pathways in skin regeneration .
  • HY-P0045
    Palmitoyl pentapeptide 4

    Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide)

    		 Collagen Others
    Palmitoyl pentapeptide 4 (Matrixyl; Palmitoyl pentapeptide 3; Matrixyl (Palmitoyl Pentapeptide) is a bioactive peptide with anti-ageing effect and has been reported used as a cosmetic ingredient [1]
  • HY-A0299
    H-Gly-Pro-Hyp-OH

    Tripeptide 29

    		 Peptides Inflammation/Immunology
    H-Gly-Pro-Hyp-OH is a collagen-derived peptide and also a dipeptidyl peptidase-4 inhibitor.\nH-Gly-Pro-Hyp-OH inhibits the activity of dipeptidyl peptidase-4 in vitro. H-Gly-Pro-Hyp-OH binds to the DNA-binding site of the JUN/FOS complex, blocks the formation of the DNA-JUN/FOS complex, and inhibits transcriptional activity. H-Gly-Pro-Hyp-OH is applicable to research related to skin photoaging, UVB-induced skin aging/photoaging, and thrombosis .
  • HY-D0889
    Glycylglycine
    1 Publications Verification

    Gly-Gly; H-Gly-Gly-OH

    		 Endogenous Metabolite Metabolic Disease
    Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
  • HY-17490
    Oxaceprol
    1 Publications Verification

    N-Acetyl-L-hydroxyproline

    		 Amino Acid Derivatives Inflammation/Immunology
    Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .
  • HY-P0097
    Nonapeptide-1
    2 Publications Verification

    Melanostatine-5

    		 Melanocortin Receptor Metabolic Disease Endocrinology Cancer
    Nonapeptide-1 (Melanostatine-5), a peptide hormone, is a selective antagonist of MC1R (Ki: 40 nM). Nonapeptide-1 is a competitive α-MSH antagonist that potently inhibits intracellular cAMP and melanosome dispersion induced by α-MSH in melanocytes (IC50: 2.5 nM and 11 nM, respectively). Nonapeptide-1 inhibits melanin synthesis, and can be used in the research of skin pigmentation and regulation of steroid production in the adrenal gland, skin cancer .
  • HY-P0102
    Dipeptide diaminobutyroyl benzylamide diacetate

    		nAChR Neurological Disease Metabolic Disease
    Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a nAChR antagonist. Dipeptide diaminobutyroyl benzylamide diacetate mimics Waglerin-1 to block neuromuscular junction nicotinic acetylcholine receptors, partially inhibits neuronal signal transduction, and relaxes muscles. Dipeptide diaminobutyroyl benzylamide diacetate reduces appearance of facial wrinkles linked to repeated muscle movement.Dipeptide diaminobutyroyl benzylamide diacetate can be used for the research of mild-to-moderate fine and coarse periocular and perioral wrinkles and periorbital ageing .
  • HY-125616
    Biotinoyl tripeptide-1

    Biotinyl-GHK; Bio-GHK

    		 Amyloid-β Reactive Oxygen Species (ROS) Neurological Disease
    Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases .
  • HY-P0064
    Palmitoyl Tetrapeptide-3

    Palmitoyl Tetrapeptide-7

    		 Interleukin Related Inflammation/Immunology
    Palmitoyl Tetrapeptide-3 (Palmitoyl Tetrapeptide-7) is a synthetic peptide corresponding to amino acids 341-344 of the human immunoglobulin heavy chain, with the ability to stimulate phagocytosis. Palmitoyl tetrapeptide-3 reduces interleukin-6 (IL-6) secretion in keratinocytes and inhibits the UVB radiation-exposure inflammatory response of skin. Palmitoyl tetrapeptide-3 It also has anti-inflammatory and anti-aging effects, reducing skin wrinkles by promoting the production of elastic fibers in the papillary dermis .
  • HY-133026
    N-Acetylcarnosine

    N-Acetyl-L-carnosine

    		 Drug Intermediate Endogenous Metabolite Inflammation/Immunology
    N-Acetylcarnosine, a natural histidine-containing dipeptide, is a source of pharmacological principal L-carnosine. N-Acetylcarnosine is a potent ophthalmic agent in human cataracts .
  • HY-125553
    Hexapeptide-10

    Serilesine

    		 Amino Acid Derivatives Others
    Hexapeptide-10 (Serilesine) is a synthetic hexapeptide. Hexapeptide-10 promotes wound healing and tissue remodeling. Hexapeptide-10 is applicable in cosmetic research .
  • HY-P5238
    Trifluoroacetyl tripeptide-2

    		Peptides Others
    Trifluoroacetyl tripeptide-2 is a tripeptide with strong cosmetic activity. Trifluoroacetyl tripeptide-2 can regulate progerin synthesis, promote extracellular matrix synthesis, and improve skin elasticity. Trifluoroacetyl tripeptide-2 has anti-wrinkle and firming effects and can be used as an anti-aging ingredient in cosmetic research .
  • HY-P1626
    Acetyl tetrapeptide-15

    		Opioid Receptor Neurological Disease
    Acetyl tetrapeptide-15 is a synthetic peptide. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway. Acetyl tetrapeptide-15 is used in the cosmetics for sensitive skin .
  • HY-P5225
    Acetyl hexapeptide-38

    		PGC-1α Others
    Acetyl hexapeptide-38 is a tissue repair promoter that targets fibroblasts in the dermis of the skin. It works by promoting collagen synthesis in the dermis and thickening of subcutaneous fat. Acetyl hexapeptide-38 can activate the skin repair mechanism, increase the collagen content in the dermis, improve the skin tissue structure, and has the activity of promoting local tissue repair. Acetyl hexapeptide-38 can be used in the field of cosmetic medicine to repair congenital soft tissue defects, reduce tear grooves and nasolabial folds, eliminate postoperative scars, and conduct micro-plastic surgery of skin tissue .
  • HY-66015
    Palmitoyl hexapeptide-12

    		Interleukin Related Endocrinology
    Palmitoyl hexapeptide-12 is a bioactive peptide. Palmitoyl hexapeptide-12 reduces IL-6. Palmitoyl hexapeptide-12 has anti-aging effects. Palmitoyl hexapeptide-12 can be used in the research of photoaging and related aging skin problems .
  • HY-P0095
    Acetyl tetrapeptide-5

    		Angiotensin-converting Enzyme (ACE) Others
    Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care .
  • HY-W129161
    Acetyl tetrapeptide-3

    		Amino Acid Derivatives Metabolic Disease
    Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring .
  • HY-118060
    Dipeptide 2

    N-Valyltryptophan; Val-Trp

    		 Angiotensin-converting Enzyme (ACE) Calcium Channel NO Synthase Cardiovascular Disease
    Dipeptide 2 (N-Valyltryptophan) is an orally active, competitive angiotensin-converting enzyme (ACE) inhibitory peptide with an IC50 of 10.50 μM. Dipeptide 2 reduces intracellular Calcium ions. Dipeptide 2 significantly increases the content of NO, inhibits the production of ET-1, and induces the phosphorylation of eNOS. Dipeptide 2 decreases the systolic and diastolic blood pressure of spontaneously hypertensive rats .
  • HY-P5255
    Oligopeptide-10

    		Bacterial Infection Inflammation/Immunology
    Oligopeptide-10 is a bioactive peptide with antimicrobial activity. Oligopeptide-10 exhibits broad-spectrum bactericidal effects against Gram-positive bacteria including Propionibacterium acnes and Staphylococcus aureus. Oligopeptide-10 targets lipoteichoic acid (LTA) on the surface of bacterial cell membranes, induces bacterial osmotic imbalance by disrupting the integrity of bacterial membranes, and reduces the release of pro-inflammatory cytokines induced by bacteria. Oligopeptide-10 possesses skin-protective activity. Oligopeptide-10 can be applied in research related to acne vulgaris, dandruff, seborrheic dermatitis, and tinea pedis .
  • HY-P3047
    Acetyl decapeptide-3

    		Peptides Others
    Ac-Decapeptide is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P5251
    Oligopeptide-68

    		Amino Acid Derivatives Metabolic Disease
    Oligopeptide-68 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P5248
    Tetrapeptide-1

    		Collagen Metabolic Disease
    Tetrapeptide-1 is a tetrapeptide exhibiting antiaging and antioxidant activity. Tetrapeptide-1 can be used for cosmetics research .
  • HY-P5250
    Palmitoyl tripeptide-5

    		MMP Others
    Palmitoyl tripeptide-5 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P5242
    Tripeptide-10 citrulline

    T10-C

    		 Peptides Others
    Tripeptide-10 citrulline (T10-C) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P3163
    Hexapeptide-9

    		PPAR Collagen SOD Inflammation/Immunology
    Hexapeptide-9 is a signaling peptide. Hexapeptide-9 can promote collagen production. Hexapeptide-9 has anti-aging activity, and can be used in cosmetic research .
  • HY-P5275
    Tripeptide-41

    CG-Lipoxyn

    		 NF-κB Histone Demethylase Metabolic Disease
    Tripeptide-41 (CG-Lipoxyn) is a signal peptide. Tripeptide-41 activates the NF-kB signaling pathway, inhibits the expression of C/EBP and increases cAMP. Tripeptide-41 is an important intracellular signaling factor that causes lipolysis by promoting the hydrolysis of lipids into triglycerides. Tripeptide-41 can be used in cosmetics that targets fat accumulation .
  • HY-P5244
    Tripeptide-32

    		Peptides Metabolic Disease
    Tripeptide-32 is a bioactive peptide that targets the PER1 gene. Tripeptide-32 can regulate circadian rhythms and stimulate the synthesis of cellular repair proteins, with anti-aging activity .
  • HY-W092109
    H-Phe-Trp-OH

    Phenylalanyltryptophan; Phe-Trp

    		 Endogenous Metabolite Neurological Disease Cancer
    H-Phe-Trp-OH (Phenylalanyltryptophan) is an endogenous metabolite. H-Phe-Trp-OH can be used in the research of hepatocellular carcinoma and tic disorders .
  • HY-P0104
    Palmitoyl tripeptide-38

    		Collagen Metabolic Disease
    Palmitoyl tripeptide-38 is a lipopeptide that increases the production of dermal and epidermal collagen, fibronectin, and hyaluronic acid. Palmitoyl tripeptide-38 is used in research related to skin aging (fine lines, wrinkles, reduced skin elasticity, decreased skin water content, uneven skin tone) .
  • HY-P2663
    Acetyl tetrapeptide-2

    		TNF Receptor Metabolic Disease
    Acetyl tetrapeptide-2 is a bio-active peptide that exhibits anti-aging activity. Acetyl tetrapeptide-2 can reduce loss of thymic factors. Acetyl tetrapeptide-2 can increase the stiffness of HaCaT cells. Acetyl tetrapeptide-2 is a stimulator of structural skin elements including collagen and elastin .
  • HY-P5247
    Palmitoyl tetrapeptide-20

    PTP20

    		 Melanocortin Receptor Sirtuin Metabolic Disease Inflammation/Immunology
    Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 can be used in research on preventing hair loss and improving hair graying .
  • HY-P2096
    Hexapeptide-11

    		Reactive Oxygen Species (ROS) ATM/ATR MDM-2/p53 MMP Keap1-Nrf2 HSP Inflammation/Immunology
    Hexapeptide-11 is an anti-aging peptide that can protect fibroblasts from premature cell senescence mediated by oxidative stress. Hexapeptide-11 is also a potential stimulator of hyaluronic acid in keratinocytes, and can enhance skin barrier function by upregulating the expression of HAS2 and EGR3, and downregulating the expression of HYAL2. Hexapeptide-11 can also improve skin elasticity .
  • HY-P0098
    [D-Ala2]leucine-enkephalin

    		Opioid Receptor Neurological Disease Inflammation/Immunology
    [D-Ala2]leucine-enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.
  • HY-P5243
    Copper tripeptide-3

    AHK-Cu

    		 Peptides Bcl-2 Family Others
    Copper tripeptide-3 (AHK-Cu) is a bioactive peptide with promotion of hair growth effect. Copper tripeptide-3 increases dermal cell proliferation and viability while increasing the deposition of collagen to renew the extracellular matrix. Copper tripeptide-3 stimulates the elongation of human hair follicles and proliferation of dermal papilla cells .
  • HY-P0099
    Pentapeptide-3

    		nAChR Others
    Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides .
  • HY-P5221
    Acetyl hexapeptide-37

    		Peptides Others
    Acetyl hexapeptide-37 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P0065
    Acetyl octapeptide-1

    		Peptides Others
    Acetyl octapeptide-1 is a bioactive peptide with anti-wrinkle effect and has been reported used as a cosmetic ingredient .
  • HY-P5232
    Tetrapeptide-21

    		Collagen Metabolic Disease
    Tetrapeptide-21 is a bioactive peptide composed of four amino acids. Tetrapeptide-21 effectively enhances the vitality of human dermal fibroblasts. Tetrapeptide-21 upregulates the expression of key extracellular matrix (ECM) genes and promotes the synthesis of ECM proteins (such as type I collagen, hyaluronic acid synthase 1, and fibronectin). Tetrapeptide-21 has the efficacy of anti-wrinkle and improving skin elasticity, and has been reported to be used as a cosmetic ingredient .
  • HY-P5253
    Octapeptide-2

    		Apoptosis Metabolic Disease
    Octapeptide-2 is a biomimetic peptide that mimics the thymosin-β4 growth factor. Octapeptide-2 can promote hair growth, reduce cell apoptosis, and increase the proliferation of keratinocytes. Octapeptide-2 can be used in the research of hair loss and alopecia areata .
  • HY-P0266
    N-Acetyl-Ser-dAsp-Lys-Pro

    Ac-SdKP

    		 Angiotensin-converting Enzyme (ACE) Cardiovascular Disease Inflammation/Immunology
    N-Acetyl-Ser-dAsp-Lys-Pro, an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site of ACE.
  • HY-134017
    Acetyl dipeptide-1 cetyl ester

    Calmosensine

    		 Peptides Others
    Acetyl dipeptide-1 cetyl ester (Calmosensine) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P5220A
    Acetyl hexapeptide-1 acetate

    Melitane acetate

    		 Melanocortin Receptor Others
    Acetyl hexapeptide-1 (Melitane) acetate is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 acetate can regulate muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 acetate is one of the components of anti-aging skin care essences targeting dynamic wrinkles. Acetyl hexapeptide-1 acetate can be used in studies related to mild photo-aged facial skin and premature graying of hair .
  • HY-66018
    Palmitoyl tripeptide-5 diTFA

    		Peptides Others
    Palmitoyl tripeptide-5 biTFA is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient .
  • HY-P10940A
    Ac-RFAAKAA-COOH TFA

    		Peptides Others
    Ac-RFAAKAA-COOH TFA is a heptapeptide with one reactive Lys residue. Ac-RFAAKAA-COOH TFA can be used for detecting skin sensitizing components in cosmetics and other substances .
  • HY-P5237
    Tetrapeptide-4

    		Collagen Others
    Tetrapeptide-4 is a synthetic tetrapeptide. Tetrapeptide-4 upregulates hyaluronic acid synthetase, and collagen production in human dermal fibroblasts. Tetrapeptide-4 reduces skin aging, improves skin firmness, elasticity, and appearance, and benefits hair .
  • HY-P4998
    Chemotactic Domain of Elastin

    		Biochemical Assay Reagents Cancer
    Chemotactic Domain of Elastin is an elastin-derived peptide with chemotactic effects on certain tumor cells, such as M27 tumor cells. Chemotactic Domain of Elastin can be used in cancer research .
  • HY-P0096
    Decapeptide-12

    		Tyrosinase Sirtuin Inflammation/Immunology Endocrinology
    Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation .
  • HY-D0889R
    Glycylglycine (Standard)

    Gly-Gly (Standard); H-Gly-Gly-OH (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    Glycylglycine (Standard) is the analytical standard of Glycylglycine (HY-D0889). This product is intended for research and analytical applications. Glycylglycine is a non-selective glycylglycine dipeptidase substrate and iNOS inhibitor. Glycylglycine can cross the cell membrane by passive diffusion and is hydrolyzed to glycine in the cell, participating in energy metabolism and antioxidant processes. Glycylglycine promotes spermatogonial stem cells (SSCs) proliferation, inhibits astrocyte overactivation and reduces nitric oxide (NO) release, while upregulating the expression of neurotrophic factors (such as PDGFA, FGF2, CNTF) to support nerve myelin repair. Glycylglycine can be used to study male reproductive biology (such as SSCs proliferation regulation) and neurodegenerative diseases (such as neuroprotective mechanisms in multiple sclerosis) .
  • HY-P5220
    Acetyl hexapeptide-1

    Melitane

    		 Melanocortin Receptor Others
    Acetyl hexapeptide-1 (Melitane) is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 regulates muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 is one of the components of anti-aging skincare serums targeting dynamic wrinkles. Acetyl hexapeptide-1 can be used in research related to mild photoaged facial skin and premature gray hair .
  • HY-P5226
    Palmitoyl tripeptide-8

    		Peptides Inflammation/Immunology
    Palmitoyl tripeptide-8 s a bioactive peptide with anti-allergen effect and has been reported used as a cosmetic ingredient .

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