26 Results for "

DMBA

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "DMBA" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-W011845
CAS No.: 57-97-6
Synonyms: 7,12-DMBA; 7,12-Dimethylbenzanthracene
Research Areas:  

Cancer

DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
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4
4 Cited Publications
Cat. No.: HY-N0679
CAS No.: 127-47-9
Synonyms: Retinol acetate; Vitamin A acetate
Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
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3
3 Cited Publications
Cat. No.: HY-B0860
CAS No.: 330-54-1
Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
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1
1 Cited Publications
Cat. No.: HY-110002
CAS No.: 62004-35-7
Purity:  99.65%
LFM-A13 is a potent BTK, JAK2, PLK inhibitor, inhibits recombinant BTK, Plx1 and PLK3 with IC50s of 2.5 μM, 10 μM and 61 μM. LFM-A13 has antiproliferative activity and anticancer activity. LFM-A13 can be used in cancer-related research
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Cat. No.: HY-126573
CAS No.: 538-24-9
Purity:  ≥98.0%
Trilaurin is an orally active triglyceride. Trilaurin inhibits DMBA-induced, croton oil-promoted skin tumor formation in Swiss Webster mice. Trilaurin increases plasma high-density lipoprotein cholesterol and apolipoprotein A-I concentrations. Trilaurin is used as an occlusive skin conditioning agent and/or non-aqueous thickener in cosmetics .
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Cat. No.: HY-Y1881A
CAS No.: 7758-99-8
Copper sulfate pentahydrate, 99% is a biochemical reagent. Copper sulfate pentahydrate, 99% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, 99% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, 99% is cytotoxic to various cells. Copper sulfate pentahydrate, 99% has antioxidant activity. Copper sulfate pentahydrate, 99% can be used in the research of diabetes, Parkinson's disease and DMBA (HY-W011845)-induced tumors .
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Cat. No.: HY-W115716
CAS No.: 26266-58-0
Synonyms: Span 85
Sorbitan trioleate (Span 85) is an orally active non-ionic surface active agent. Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer .
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Cat. No.: HY-N0679R
CAS No.: 127-47-9
Synonyms: Retinol acetate (Standard); Vitamin A acetate (Standard)
Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
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Cat. No.: HY-B0860S
CAS No.: 1007536-67-5
Diuron-d6 is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
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Cat. No.: HY-W011845R
CAS No.: 57-97-6
Synonyms: 7,12-DMBA (Standard); 7,12-Dimethylbenzanthracene (Standard)
Research Areas:  

Cancer

DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models .
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Cat. No.: HY-178227
CAS No.: 2319609-67-9
KY19334 is a CXXC5-DVL inhibitor. KY19334 can activate the Wnt/β-catenin pathway by inhibiting CXXC5-Dvl interaction. KY19334 can inhibit cancer cells proliferation, migration, invasion and transformation by inhibiting CDK1. KY19334 can accelerate wound healing and exert regenerative effects. KY19334 can be used for the researches of cancer, inflammation, metabolic and neurological disease, such as cutaneous squamous cell carcinoma and diabetes .
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Cat. No.: HY-N15456
CAS No.: 178884-07-6
Cryptolepinone is a quinone reductase activator with a CD (concentration required to double induction) value of 0.02 μg/mL and can be found in Sida acuta. In the mouse mammary organ culture assay, 10 μg/mL of Cryptolepinone inhibited 83.3% of the preneoplastic lesions induced by DMBA (HY-W011845). Cryptolepinone can be used in anti-cancer research .
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Cat. No.: HY-160702
CAS No.: 2923885-49-6
Research Areas:  

Cancer

DMBA-SIL-Mal-MMAE is a cytotoxin-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked DMBA-SIL-Mal .
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Cat. No.: HY-B0860R
CAS No.: 330-54-1
Diuron (Standard) is the analytical standard of Diuron (HY-B0860). This product is intended for research and analytical applications. Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research .
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Cat. No.: HY-160703
CAS No.: 2923885-47-4
Target:  

Drug Intermediate

Research Areas:  

Cancer

DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research .
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Cat. No.: HY-175760
Target:  

Cytochrome P450

Research Areas:  

Cancer

CYP1B1-IN-11 (Compound M2) is a selective CYP1B1 inhibitor with an IC50 of 0.00605 pM. CYP1B1-IN-11 effectively reverses DMBA (HY-W011845)-induced Paclitaxel (HY-B0015) resistance and CYP1B1-IN-11 suppresses tumor cells invasion and migration. CYP1B1-IN-11 can be used for tumor drug resistance research .
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Cat. No.: HY-126573R
CAS No.: 538-24-9
Trilaurin (Standard) is the analytical standard of Trilaurin. This product is intended for research and analytical applications. Trilaurin could inhibit the formation of neoplasms initiated by dimethylbenzanthracene (DMBA) and promoted by croton oil .
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Cat. No.: HY-W543743
CAS No.: 17088-21-0
Synonyms: 1-Vinylpyrene
Research Areas:  

Cancer

1-Ethenylpyrene (1-Vinylpyrene) is an anti-chemical carcinogen that inhibits the formation of skin tumors initiated by either DMBA (HY-W011845) or Benzo[a]pyrene (HY-107377) .
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Cat. No.: HY-19590
CAS No.: 87719-32-2
Synonyms: Ro 15-1570
Target:  

Drug Derivative

Research Areas:  

Cancer

Etarotene (Ro 15-1570) is a derivative of Arotinoid (HY-106735). Etarotene is an orally active antitumor agent against DMBA (HY-W011845)-induced mammary tumor and causes toxic symptoms of hypervitaminosis A in rat model .
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Cat. No.: HY-124403
CAS No.: 83364-03-8
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

D 15413 is an orally active antagonist for nonsteroidal estrogen. D 15413 inhibits growth of estrogen receptor positive MCF-7 cell with an inhibition rate of 70% at 10 -7 M. D 15413 exhibits antitumor efficacy against DMBA (HY-W011845) or MNU (HY-34758)-induced breast cancer .
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