CYP1B1-IN-11
CYP1B1-IN-11 (Compound M2) is a selective CYP1B1 inhibitor with an IC50 of 0.00605 pM. CYP1B1-IN-11 effectively reverses DMBA (HY-W011845)-induced Paclitaxel (HY-B0015) resistance and CYP1B1-IN-11 suppresses tumor cells invasion and migration. CYP1B1-IN-11 can be used for tumor drug resistance research.
For research use only. We do not sell to patients.
- Formula: C18H17ClFN3O
- Molecular Weight:345.80
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
CYP1B1 0.00605 pM (IC50) |
CYP1A2 1615 nM (IC50) |
CYP1A1 8.3 nM (IC50) |
Chemical Information
-
Molecular Weight 345.80
-
Formula C18H17ClFN3O
-
SMILES
CNC1=C2C=CC=CC2=NC(/C=C/C3=C(OC)C=CC=C3F)=N1.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)