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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
DMP
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "DMP" in MCE Product Catalog:
17
17 Publications Verification
Synonyms: DMP 266; EFV; L-743726
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DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
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DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.
Cat. No.: HY-W004883
CAS No.: 1193-71-1
Synonyms: 5A-DMP
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3-Amino-4,6-dimethylpyridine (5A-DMP) is a UHRF1 inhibitor that targets the Arg-binding cavity site within the UHRF1 TTD domain. 3-Amino-4,6-dimethylpyridine disrupts the interaction between UHRF1 and LIG1, interfering with DNA methylation, and can be utilized in cancer research .
Cat. No.: HY-W612975
CAS No.: 1541-81-7
4-Dodecylmorpholine (DMP) is a surfactant with antimalarial activity. It can be used as a hydrophilic enzyme detergent and is commonly used as an extraction collector in reverse foam preparation processes .
Cat. No.: HY-12132
CAS No.: 202579-74-6
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DMP 904 is a noncompetitive full corticotropin-releasing factor receptor (CRFR) antagonist. DMP 904 can inhibit CRF-stimulated adenylate cyclase activity and ACTH release. DMP 904 exhibits anti-depressant and anti-anxiety activity .
Synonyms: XR-543
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DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer .
Cat. No.: HY-117747
CAS No.: 151867-81-1
Synonyms: JCR 424; XM 323
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DMP 323 is a potent, nonpeptide cyclic urea inhibitor of HIV protease, effective against both HIV type 1 and type 2. Designed using structural information and database searching, it competitively inhibits the cleavage of both peptide and HIV-1 gag polyprotein substrates. DMP 323 shows comparable potency to other highly effective HIV protease inhibitors like A-80987 and Ro-31-8959. Importantly, its efficacy against HIV protease remains unaffected by human plasma or serum, suggesting low affinity for plasma proteins. Furthermore, DMP 323 demonstrates minimal inhibition of various mammalian proteases at concentrations much higher than those needed for HIV protease inhibition, highlighting its specificity for viral targets .
Cat. No.: HY-105148
CAS No.: 174391-92-5
Synonyms: DMP-450
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Mozenavir (DMP 450) is an orally active and highly selective inhibitor of HIV-1 protease (Ki=0.3 nM). Mozenavir blocks the cleavage and processing of viral polyproteins, inhibiting the replication and maturation of HIV-1. Mozenavir is promising for research of HIV infection .
Cat. No.: HY-10572B
CAS No.: 177530-93-7
Synonyms: (Rac)-DMP 266; (Rac)-EFV; (Rac)-L-743726
(Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
Cat. No.: HY-10572R
CAS No.: 154598-52-4
Synonyms: DMP 266 (Standard); EFV (Standard); L-743726 (Standard)
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Cat. No.: HY-10572A
CAS No.: 154801-74-8
Synonyms: (R)-DMP 266; (R)-EFV; (R)-L-743726
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(R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms .
Cat. No.: HY-10572S1
CAS No.: 1261394-62-0
Synonyms: DMP 266-13C6; EFV-13C6; L-743726-13C6
Cat. No.: HY-10572S
CAS No.: 1132642-95-5
Cat. No.: HY-125615
CAS No.: 155158-97-7
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DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .
Cat. No.: HY-106921
CAS No.: 144849-63-8
Synonyms: DMP 840 free base
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Bisnafide (DMP 840) is an anticancer agent .
Cat. No.: HY-RS03826
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DMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for DMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
