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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
DMP
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "DMP" in MCE Product Catalog:
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20 Publications Verification
別名: DMP 266; EFV; L-743726
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
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DMP 777 is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.
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1 Cited Publications
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DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of anxiety and depression.
製品番号: HY-W004883
CAS 番号: 1193-71-1
別名: 5A-DMP
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研究分野:
3-Amino-4,6-dimethylpyridine (5A-DMP) is a UHRF1 tandem Tudor domain binder (Kd = 19.3 μM). 3-Amino-4,6-dimethylpyridine thermally stabilizes isolated UHRF1 TTD and disrupts the full-length UHRF1-LIG1 complex at this site. 3-Amino-4,6-dimethylpyridine binds the regulatory arginine-binding cavity, blocks the LIG1/LIG1K126me3 interaction, and displaces H3K9me3 and LIG1K126me3 peptides from the TTD groove. 3-Amino-4,6-dimethylpyridine causes growth defects in cancer cell lines at high concentrations. 3-Amino-4,6-dimethylpyridine can be used for research on colorectal cancer .
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製品番号: HY-W612975
CAS 番号: 1541-81-7
4-Dodecylmorpholine (DMP) is a surfactant with antimalarial activity. It can be used as a hydrophilic enzyme detergent and is commonly used as an extraction collector in reverse foam preparation processes .
製品番号: HY-12132
CAS 番号: 202579-74-6
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DMP 904 is a noncompetitive full corticotropin-releasing factor receptor (CRFR) antagonist. DMP 904 can inhibit CRF-stimulated adenylate cyclase activity and ACTH release. DMP 904 exhibits anti-depressant and anti-anxiety activity .
別名: XR-543
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DMP-543 (XR-543) is a KV7 channel blocker, also acts as a potent neurotransmitter release enhancer .
製品番号: HY-105148
CAS 番号: 174391-92-5
別名: DMP-450
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Mozenavir (DMP-450) is an orally active cyclic urea HIV-1 protease inhibitor with an IC50 of 76 nM. Mozenavir inhibits replication by targeting viral protease, blocks viral polyprotein processing, and induces the production of core-uncondensed, immature, non-infectious viral particles in chronically infected cells. Mozenavir is applicable to research related to HIV infection .
製品番号: HY-117747
CAS 番号: 151867-81-1
別名: JCR 424; XM 323
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DMP 323 is a potent, nonpeptide cyclic urea inhibitor of HIV protease, effective against both HIV type 1 and type 2. Designed using structural information and database searching, it competitively inhibits the cleavage of both peptide and HIV-1 gag polyprotein substrates. DMP 323 shows comparable potency to other highly effective HIV protease inhibitors like A-80987 and Ro-31-8959. Importantly, its efficacy against HIV protease remains unaffected by human plasma or serum, suggesting low affinity for plasma proteins. Furthermore, DMP 323 demonstrates minimal inhibition of various mammalian proteases at concentrations much higher than those needed for HIV protease inhibition, highlighting its specificity for viral targets .
製品番号: HY-10572B
CAS 番号: 177530-93-7
別名: (Rac)-DMP 266; (Rac)-EFV; (Rac)-L-743726
(Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
製品番号: HY-10572R
CAS 番号: 154598-52-4
別名: DMP 266 (Standard); EFV (Standard); L-743726 (Standard)
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製品番号: HY-10572A
CAS 番号: 154801-74-8
別名: (R)-DMP 266; (R)-EFV; (R)-L-743726
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研究分野:
(R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms .
製品番号: HY-10572S1
CAS 番号: 1261394-62-0
別名: DMP 266-13C6; EFV-13C6; L-743726-13C6
製品番号: HY-10572S
CAS 番号: 1132642-95-5
製品番号: HY-125615
CAS 番号: 155158-97-7
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DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .
製品番号: HY-106921
CAS 番号: 144849-63-8
別名: DMP 840 free base
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Bisnafide (DMP 840) is an anticancer agent .
製品番号: HY-RS03826
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DMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for DMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
