22 Results for "

Env

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Env" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-135474
CAS No.: 304481-60-5
Purity:  99.67%
Research Areas:  

Others

KM91104 is a cell-permeable V-ATPase a3-b2 inhibitor (IC50 = 2.3 µM). KM91104 reduces the metabolic activity, cell proliferation capacity and V-ATPase subunit protein expression levels of primary human hepatic stellate cells, increases intracellular ATP levels and decreases cytoplasmic pH. KM91104 reduces TLR4 expression on the surface of oligodendrocyte precursor cells, blocks the ENV-TLR4 interaction, and reverses oligodendrocyte myelination defects induced by ENV protein .
loading...
    loading...
Cat. No.: HY-Y0788
CAS No.: 496-15-1
Indoline is a derivative of Indole (HY-W001132). Indoline can use as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the HIV-1 envelope glycoprotein (Env) in advance, and causes viral inactivation. Indoline binds to gp120. Indoline CD4mcs can inhibit HIV-1AD8 with an IC50 in the micromolar range .
loading...
    loading...
Cat. No.: HY-P991246

Target:  

Virus Protease HIV

Research Areas:  

Infection

VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env). VRC01LS blocks the binding of HIV-1 to host cell CD4 receptor, inhibiting viral entry. VRC01LS is promising for research of HIV-1 infection .
loading...
    loading...
Cat. No.: HY-P10310A
Target:  

HIV

Research Areas:  

Infection

F9170 TFA is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 TFA targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 TFA is able to cross the blood-brain barrier (BBB) .
loading...
    loading...
Cat. No.: HY-125183
CAS No.: 2974489-09-1
Target:  

HIV

Research Areas:  

Infection

BMS-818251 is a HIV-1 attachment and entry inhibitor. BMS-818251 binds to HIV-1 Env gp120, interferes with viral attachment and entry processes, and inhibits HIV-1 viral replication. BMS-818251 can be used in studies related to HIV-1 infection .
loading...
    loading...
Cat. No.: HY-P10310
CAS No.: 2305092-66-2
Target:  

HIV

Research Areas:  

Infection

F9170 is an amphipathic peptide with an activity of inactivate HIV-1 virions. F9170 targets the conserved cytoplasmic tail of HIV-1 env and disrupts the integrity of the viral membrane. F9170 is able to cross the blood-brain barrier (BBB) .
loading...
    loading...
Cat. No.: HY-Y0788R
CAS No.: 496-15-1
Indoline (Standard) is an analytical standard for Indoline (HY-Y0788). This product is intended for research and analytical applications. Indoline is a HIV-1 envelope glycoprotein gp120 binder. Indoline binds to the conserved CD4-binding site of gp120 (the Phe 43 cavity and its surrounding vestibule), competitively blocks the binding of CD4, and prematurely triggers conformational changes of the Env trimer, resulting in viral inactivation. Indoline induces the conformational opening of HIV-1 Env on infected cells, exposes vulnerable epitopes, increases antibody recognition rate, enhances the binding of FcγRIIIa receptors, and sensitizes infected cells to antibody-dependent cellular cytotoxicity. Indoline is a derivative of Indole (HY-W001132). Indoline can be used in studies related to HIV-1 infection .
loading...
    loading...
Cat. No.: HY-139989
CAS No.: 2411819-82-2
Purity:  99.53%
Target:  

HIV

Research Areas:  

Infection

NBD-14270, a pyridine analogue, is a potent HIV-1 entry antagonist with an IC50 of 180 nM against 50 HIV-1 Env-pseudotyped viruses. NBD-14270 binds to HIV-1 gp120 and shows potent antiviral activity. NBD-14270 shows low cytotoxicity (CC50>100 μM) .
loading...
    loading...
Cat. No.: HY-110253
CAS No.: 331261-50-8
Synonyms: HIV-1 inhibitor 18A
Target:  

HIV

Research Areas:  

Infection

18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env .
loading...
    loading...
Cat. No.: HY-RS04518
Research Areas:  

Others

ERVW-1 Human Pre-designed siRNA Set A contains three designed siRNAs for ERVW-1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-122256
CAS No.: 410545-90-3
Target:  

HIV Integrase

Research Areas:  

Infection

L-870812 is a HIV-1 integration with integrase strand transfer inhibitor. L-870812 consistently blocks cell-free and cell-associated HIV-1 infection. L-870812 blocks subtype C and CRFO2_AG primary isolates. L-870812 can be used for the study of replication-deficient HIV-1 Ba-L (env) pseudovirus .
loading...
    loading...
Cat. No.: HY-P74118
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74119
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74120
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74121
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Envelope glycoprotein gp160; Env polyprotein; gp120; gp41; Env
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78451
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185erbB2; TKR1; ERBB2; HER-2/neu; NEU; Env; EnvW; ERVWE1; HERV-7q; HERV-W-Env; HERV7Q; HERVW; HERVWEnv
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78138
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; NGL; p185erbB2; TKR1; ERBB2; HER-2/neu; NEU; Env; EnvW; ERVWE1; HERV-7q; HERV-W-Env; HERV7Q; HERVW; HERVWEnv
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P700887
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; NGL; TKR1; ERBB2; NEU; Env; EnvW; ERVWE1; HERV7Q; HERVW
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P705027
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD340; EGFR2; ErbB2; HER2; HER-2; herstatin; MLN 19; MLN19; NGL; TKR1; ERBB2; NEU; Env; EnvW; ERVWE1; HERV7Q; HERVW
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-117855
CAS No.: 1427304-84-4
Target:  

HIV

Research Areas:  

Infection

NBD-11021 is a HIV-1 entry antagonist and CD4 antagonist. NBD-11021 binds to the Phe43 cavity of HIV-1 gp120 and competitively blocks the gp120-CD4 interaction . NBD-11021 exhibits broad-spectrum inhibitory activity against 56 HIV-1 Env pseudoviruses of different subtypes, with an IC50 of 0.6-5.3 μM. NBD-11021 inhibits CCR5- and CXCR4-tropic HIV-1, primary HIV-1, drug-resistant HIV-1, HIV-1 Env-mediated cell fusion and intercellular viral transmission. NBD-11021 can be used in studies related to HIV-1 gp120, viral entry and HIV infection .
loading...
    loading...