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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
FGF19
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "FGF19" in MCE Product Catalog:
1
Cat. No.: HY-RS04895
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FGF19 Human Pre-designed siRNA Set A contains three designed siRNAs for FGF19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990414
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Cat. No.: HY-RS23234
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Fgf19 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fgf19 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-147515
CAS No.: 2396664-85-8
FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity .
Cat. No.: HY-174703
Human FGF19 mRNA encodes the human fibroblast growth factor 19 (FGF19) protein, a member of the fibroblast growth factor (FGF) family. FGF19 probably involves in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades.
Cat. No.: HY-P70583AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Fibroblast growth factor 19; FGF-19; FGF19
Cat. No.: HY-P704607
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuFGF-19; FGF19
Cat. No.: HY-179381
CAS No.: 3053546-73-6
FGFR4-IN-24 is a selective irreversible covalent FGFR4 inhibitor (IC50 = 1.2 nM). FGFR4-IN-24 shows much weaker activity against the other three FGFR family kinases (FGFR1-3). FGFR4-IN-24 inhibits the FGF19/FGFR4 signaling pathway, effectively suppressing the proliferation of the HuH-7 HCC cell line (GI50 = 17 nM). FGFR4-IN-24 exhibits significant antitumor activity in a HuH-7 mouse xenograft model. FGFR4-IN-24 can be used for the research of hepatocellular carcinoma .
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Homocholic acid is a synthetic steroid analogue. Homocholic acid can be labeled with 75Se and is used for SeHCAT detection (a method for diagnosing bile acid malabsorption) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
