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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
GDNF Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "GDNF Receptor" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) . BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine kinase RetA function .
Cat. No.: HY-136832
CAS No.: 110514-35-7
Research Areas:
Noribogaine hydrochloride is an orally active, blood-brain barrier permeable SERT inhibitor (IC50=50-300 nM) and hERG channel blocker. Noribogaine hydrochloride enhances serotonergic transmission, activates the κ-opioid receptor (OPRK) G protein signaling pathway and inhibits β-arrestin recruitment. Meanwhile, Noribogaine hydrochloride blocks the μ-opioid receptor (OPRM) signaling pathway as well as ion channels associated with cardiac repolarization. Noribogaine hydrochloride induces neuritogenesis, upregulates GDNF mRNA expression, and modulates opioid tolerance. Noribogaine hydrochloride reduces alcohol-seeking behavior in experimental animals, and is widely used in studies related to depression, addiction, alcoholism, and cardiotoxicity .
Synonyms: XIB4035
Target:
Research Areas:
(E)-Aminoquinol (XIB4035) is a GFRα-1 agonist. (E)-Aminoquinol has mimic neurotrophic effects of GDNF, and induces Ret autophosphorylation in Neuro-2A cells. (E)-Aminoquinol can be used for research of Parkinson’s disease .
Cat. No.: HY-N16499
CAS No.: 157207-54-0
Cat. No.: HY-163840
Target:
Research Areas:
GFRα2/3-IN-1 (Compound 16) is a selective GFRα2/3 inhibitor with IC50 values of 0.1 and 0.2 μM for GFRα2 and GFRα3, respectively. GFRα2 is a glial cell line-derived neurotrophic factor (GDNF) receptor related to GFRα1, GFRα2/3-IN-1 can be used for pain and itch research .
Cat. No.: HY-119910A
CAS No.: 10023-54-8
Synonyms: (E/Z)-XIB4035
Target:
Research Areas:
Aminoquinol is a GFRα-1 agonist. Aminoquinol exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol can be used in research related to Parkinson's disease .
Cat. No.: HY-119910B
CAS No.: 7195-12-2
Synonyms: (E/Z)-XIB4035 phosphate
Target:
Research Areas:
Aminoquinol ((E/Z)-XIB4035) phosphate is a GFRα-1 agonist. Aminoquinol phosphate exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol phosphate can be used in research related to Parkinson's disease .
Cat. No.: HY-119910C
CAS No.: 3653-53-0
Synonyms: (E/Z)-XIB4035 triphosphate
Target:
Research Areas:
Aminoquinol ((E/Z)-XIB4035) phosphate is a GFRα-1 agonist. Aminoquinol phosphate exhibits neurotrophic effects similar to GDNF and induces Ret autophosphorylation in Neuro-2A cells. Aminoquinol phosphate can be used in research related to Parkinson's disease .
Cat. No.: HY-111969R
CAS No.: 924811-53-0
Target:
Research Areas:
BT18 (Standard) is the analytical standard of BT18 (HY-111969). This product is intended for research and analytical applications. BT18 is a molecule mimic with function similar to glial cell line-derived neurotrophic factor (GDNF) . BT18 shows an effect on GDNF family receptor GFRα1 and RET receptor tyrosine Kinase RetA function .
Cat. No.: HY-P77373
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Species:
Human
Source:
HEK293
Cat. No.: HY-P76951
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76952
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P77372
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: GFRA3; GFR-Alpha-3; GDNF Family Receptor Alpha 3; GFRa-3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GDNF Receptor Alpha-3; GPI-Linked Receptor; GDNFR-Alpha-3; GDNFR3
Species:
Human
Source:
HEK293
Cat. No.: HY-P70384
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF Receptor Alpha 1d; GDNFR; GDNF Receptor Alpha 1e; RET1L; GFR-Alpha-1; TGF-Beta-Related Neurotrophic Factor Receptor 1; GFRalpha-1; GDNF Receptor Alpha-1; RHDA4; GDNF Family Receptor Alpha 1; RET Ligand 1
Species:
Human
Source:
HEK293
Cat. No.: HY-P76948
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GFRA1; GDNFR-Alpha-1; Prev. GDNFRA; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha; RETL1; PI-Linked Cell-Surface Accessory Protein; TRNR1; GPI-Linked Anchor Protein; GDNF Family Receptor Alpha-1; Alternative Protein GFRA1; GFR-ALPHA-1; GDNF Receptor Alpha 1d; GDNFR; GDNF Receptor Alpha 1e; RET1L; GFR-Alpha-1; TGF-Beta-Related Neurotrophic Factor Receptor 1; GFRalpha-1; GDNF Receptor Alpha-1; RHDA4; GDNF Family Receptor Alpha 1; RET Ligand 1
Species:
Rat
Source:
HEK293
Cat. No.: HY-P702624
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Species:
Rat
Source:
HEK293
Cat. No.: HY-P704308
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Species:
Human
Source:
HEK293
Cat. No.: HY-P704634
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: GFRAL; GRAL; Prev. C6orf144; Chromosome 6 Open Reading Frame 144; BA360D14.1; IVFI9356; UNQ9356; GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
