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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
GLUT3
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "GLUT3" in MCE Product Catalog:
65
65 Publications Verification
Target:
研究分野:
BAY-876, a chemical probe, is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [3].
8
8 Cited Publications
Target:
研究分野:
KL-11743 is a potent, orally active, and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. KL-11743 specifically blocks glucose metabolism. KL-11743 can synergize with electron transport inhibitors to induce cell death. In addition, KL-11743 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [3] .
2
2 Cited Publications
Target:
GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases .
2
2 Cited Publications
製品番号: HY-W179181
CAS 番号: 852702-51-3
Target:
研究分野:
MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC50 of 0.10 mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a Ki of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes .
製品番号: HY-W047324
CAS 番号: 34213-86-0
別名: 4-Aminophenylmannoside, 98%
Target:
研究分野:
4-Aminophenyl-α-D-mannopyranoside, 98% is a mannopyranoside. 4-Aminophenyl-α-D-mannopyranoside, 98%, after conjugation to the surface of liposomes, can enhance delivery to the mouse brain via GLUT1- and GLUT3-mediated transport. 4-Aminophenyl-α-D-mannopyranoside, 98% can be detected as a characteristic glycoside in the metabolomics of fermented foods and is considered a potential health-related metabolic marker. 4-Aminophenyl-α-D-mannopyranoside, 98% can be used in studies of glycosylation processes and enzyme-substrate interactions [3].
製品番号: HY-167857
CAS 番号: 350993-69-0
(Rac)-Glutipyran is a broad-spectrum GLUT inhibitor that targets both GLUT1 and GLUT3. (Rac)-Glutipyran inhibits glucose uptake and suppresses the growth of multiple cancer cells, significantly inhibiting PANC-1 cell growth (IC50=1.8 μM) and glucose uptake (IC50=0.13 μM) .
製品番号: HY-P703200
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: SLC2A3; Solute Carrier Family 2, Facilitated Glucose Transporter Member 3; Prev. GLUT3; GLUT-3; Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3; Solute Carrier Family 2 Member 3; Glucose Transporter Type 3, Brain
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-167857S
製品番号: HY-RS13168
Target:
研究分野:
Slc2a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc2a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS13167
Target:
研究分野:
SLC2A3 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC2A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-RS13169
Target:
研究分野:
SLC2A3 Rat Pre-designed siRNA Set A contains three designed siRNAs for SLC2A3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
製品番号: HY-100017R
CAS 番号: 1799753-84-6
Target:
研究分野:
BAY-876 (Standard) is the analytical standard of BAY-876 (HY-100017). This product is intended for research and analytical applications. BAY-876, a chemical probe, is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth. In addition, BAY-876 can induce the formation of disulfide bonds in actin cytoskeletal proteins, leading to the occurrence of cellular disulfidptosis [3].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
