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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
GlyR
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "GlyR" in MCE Product Catalog:
73
5
Category:
Natural Products Other disease Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
3
3 Cited Publications
Target:
GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor extracted from patent WO 2017066459 A1. GlyRS-IN-1 can also inhibit the growth of bacteria .
Category:
Microorganisms Anti-aging Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-41700S
CAS No.: 177614-69-6
Synonyms: (R)-Alanine-d3; Ba 2776-d3; D-α-Alanine-d3
Target:
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Research Areas:
PSEM 89S TFA is a selective and brain penetrant agonists for the resulting ion channels. PSEM 89S TFA is orthogonally selective for Q79G and L141F, respectively .
Cat. No.: HY-161182
CAS No.: 2341841-08-3
uPSEM792 hydrochloride is a PSAM 4-GlyR agonist .
Category:
Cat. No.: HY-161246
CAS No.: 2323525-19-3
Target:
Research Areas:
uPSEM792 is a pharmacologically selective effector molecules (PSEM) agonist for PSAM 4-GlyR, with an affinity of Ki of 0.7 nM. uPSEM792 is a substrate for efflux transporters in brains of wild type and dual P-gp and BCRP knockout mice. uPSEM7952 is a possible lead for developing the PET radioligand for PSAM 4-GlyR .
Cat. No.: HY-41700S1
CAS No.: 1202063-27-1
Synonyms: (R)-Alanine-d4; Ba 2776-d4; D-α-Alanine-d4
Cat. No.: HY-113329R
CAS No.: 543-18-0
Synonyms: Taurocyamine (Standard)
Synonyms: ACEA-1021
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Licostinel (ACEA-1021) is a glycine receptor antagonist (IC50: 59 nM). Licostinel has neuroprotective activity .
Cat. No.: HY-P11374
Target:
Research Areas:
Cat. No.: HY-41700S5
CAS No.: 286460-72-8
Synonyms: (R)-Alanine-13C3; Ba 2776-13C3; D-α-Alanine-13C3
Cat. No.: HY-147367
CAS No.: 2079895-60-4
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Research Areas:
AM-1488 is a potent, orally active glycine receptor (GlyR) potentiator (hGlyRα3 EC50=0.45 μM) .
Cat. No.: HY-16569S
CAS No.: 1217651-73-4
Cat. No.: HY-16569S1
CAS No.: 1217625-62-1
Cat. No.: HY-107526
CAS No.: 405225-21-0
Synonyms: (Rac)-NFPS
Target:
Research Areas:
NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC50s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively . NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
