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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
H5N1
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "H5N1" in MCE Product Catalog:
44
44 Cited Publications
Category:
Infection Quinones Microorganisms Benzene Quinones Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-P991059
CAS No.: 2043950-09-8
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Cat. No.: HY-130178
CAS No.: 1210501-46-4
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CL-385319 is an N-substituted piperidine compound with inhibitory activity against H5N1 avian influenza A virus infection. CL-385319 exhibited an IC50 of 27.03±2.54 μM against infection of highly pathogenic H5N1 virus in Madin-Darby canine kidney cells (MDCK). CL-385319 had low cytotoxicity with a CC50 of 1.48 mM and was able to inhibit the entry of pseudoviruses carrying H5N1 strains from different sources, but had no inhibitory effect on the entry of VSV-G pseudotyped particles. Pseudoviruses with the M24A mutation in HA1 or the F110S mutation in HA2 were resistant to CL-385319, indicating that these two residues in the cavity region may be critical for the binding of CL-385319 .
Cat. No.: HY-177637
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H5N1 aptamer sodium is a DNA aptamer targeted to H5N1 Avian Influenza Virus.
Cat. No.: HY-15230R
CAS No.: 30562-34-6
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Cat. No.: HY-146306
CAS No.: 2217630-64-1
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Neuraminidase-IN-9 (Compound 6l) is a potent influenza neuraminidase inhibitor with IC50 values of 0.12, 0.049 and 0.16 µM against H5N1, H5N2 and H5N6, respectively .
Cat. No.: HY-163393
CAS No.: 2935407-32-0
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Neuraminidase-IN-18 (compound N5) is a novel polyheterocyclic neuraminidase (NA) inhibitor. Neuraminidase-IN-18 shows potency in inhibition of H5N1 NA with an IC50 of 0.14 μM and 0.27 μM against the wild-type H5N1 NA and H5N1-H274Y mutant NA, respectively. Neuraminidase-IN-18 inhibits influenza virus replication by binding to NAs in cell level .
Cat. No.: HY-N8399
CAS No.: 95258-13-2
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Simaroubaceae Extract Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology Brucea javanica (L.) Merr.
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Cat. No.: HY-149088
CAS No.: 3049424-11-2
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Neuraminidase-IN-16 (Compound 43b) is a potent neuraminidase inhibitor with IC50s of 0.031, 0.15, 0.25, 0.60, 0.63 and 10.08 μM against neuraminidase of H5N1, H5N8, H1N1, H3N2, H5N1-H274Y and H1N1-H274Y, respectively .
Cat. No.: HY-123466
CAS No.: 1290611-29-8
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GP-1681 is a Beraprost sodium (HY-13569A) analogue. GP-1681 can be used in the research of influenza A H5N1 infection .
Cat. No.: HY-163522
CAS No.: 3040120-35-9
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Neuraminidase-IN-20 (Compound 5i) is a potent inhibitor of mutant neuraminidase (NA) (H5N1-H274Y) (IC50= 0.44 μM).Neuraminidase-IN-20 binds to the 430 cavity site of NA and disrupts the enzymatic activity of NA .
Cat. No.: HY-144103
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Neuraminidase-IN-4 (Compound 4b) is a potent inhibitor of neuraminidase with an EC50 of 1.59 μM. Neuraminidase (NA) is an important target for the research of influenza. Neuraminidase-IN-4 exhibits excellent antiviral activity against A/chicken/Hubei/327/2004 (H5N1-DW) .
Cat. No.: HY-151104
CAS No.: 2685786-28-9
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Neuraminidase-IN-11 (15e) is a potent and selective neuraminidase (NA) inhibitor with the IC50 values of 4.7 nM, 8.46 nM and 1.5 nM against H1N1, H5N1 and H5N8 NAs respectively .
Cat. No.: HY-157249
CAS No.: 2739990-96-4
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Antiviral agent 43 (compound 16) is a potent and orally active influenza A viruses entry inhibitor. Antiviral agent 43 inhibits replications of influenza A strains VH04-H5N1 and PR8-H1N1 with EC50s of 240 nM and 72 nM, respectively .
Cat. No.: HY-139991
CAS No.: 2699874-41-2
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Neuraminidase-IN-3 (compound 23d) is a potent influenza neuraminidase (NA) inhibitor with IC50 values of 0.73, 0.26, and 0.63 nM against H1N1, H5N1, and H5N8 NAs, respectively .
Cat. No.: HY-151103
CAS No.: 2685786-29-0
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Neuraminidase-IN-10 is a potent neuraminidase (NA) inhibitor with anti-influenza activity. Neuraminidase-IN-10 is against H1N1, H5N1, and H5N8 with IC50 values of 2.6 nM, 5.1 nM, and 1.65 nM, respectively .
Cat. No.: HY-187427
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LMed 93 is an antiviral agent. LMed 93 inhibits the activity of influenza A virus RNA polymerase. LMed 93 suppresses viral RNA synthesis. LMed 93 inhibits the replication of influenza A viruses H5N1 and H1N1. LMed 93 can be used for the research of influenza A virus infections (H1N1, H5N1) .
Cat. No.: HY-170445
CAS No.: 3091058-28-2
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Neuraminidase-IN-23 (33c) is a potent neuraminidase (NA) inhibitor against influenza virus, with IC50 values of 0.049 μM (H1N1), 0.26 μM (H3N2), 0.17 μM (H5N1), 0.013 μM (H5N8) and 0.74 μM (H5N1-H274Y), respectively .
Cat. No.: HY-N20516
Synonyms: Edible bird's nest extract extract; Bird's nest extract
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
