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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
HCV entry inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "HCV entry inhibitor" in MCE Product Catalog:
13
13 Cited Publications
Synonyms: Block lipid transport-1
Target:
Research Areas:
BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .
2
2 Cited Publications
Cat. No.: HY-N0248
CAS No.: 58316-41-9
Category:
Infection Triterpenes Umbelliferae Extract Terpenoids Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray
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Cat. No.: HY-P991200
Cat. No.: HY-N7934
CAS No.: 34209-69-3
Synonyms: (-)-Trachelogenin
Category:
Lignans Rhaponticum carthamoides (Willd.) Iljin Plants Infection Monophenols Phenols Phenylpropanoids Compositae Extract Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-P10974
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Research Areas:
Cat. No.: HY-144107
CAS No.: 2425805-22-5
HCV-IN-34 (compound 3i) is an orally active and potent HCV entry inhibitor. HCV-IN-35 shows excellent antiviral activity, with an EC50 of 0.010 μM and a CC50 (half-maximal cytotoxic concentration) of 8.23 μM .
Cat. No.: HY-144110
CAS No.: 2425804-98-2
HCV-IN-37 (Compound 3d) is a potent inhibitor of HCV. HCV-IN-37 is orally available and long-lasting in rat plasma after oral administration to rats by a single dose of 15 mg/kg. The high potency of active derivative HCV-IN-37 is primarily driven by the inhibitory effect on the virus entry stage .
Cat. No.: HY-144109
CAS No.: 2757963-81-6
HCV-IN-36 (compound (S)-3h) is an orally active and potent HCV entry inhibitor. HCV-IN-36 shows excellent antiviral activity, with an EC50 of 0.016 μM and a CC50 (half-maximal cytotoxic concentration) of 8.78 μM .
Cat. No.: HY-118932
CAS No.: 301211-35-8
HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread .
Cat. No.: HY-153837
CAS No.: 223603-41-6
ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
Cat. No.: HY-153837A
ISIS 14803 sodium is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits protein expression in cell culture.
Cat. No.: HY-N0248R
CAS No.: 58316-41-9
Category:
Triterpenes Umbelliferae Extract Terpenoids Plants Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
Cat. No.: HY-182679
CAS No.: 2085271-43-6
L0909 is an HCV inhibitor with an EC50 of 0.022 μM. L0909 blocks HCV replication by inhibiting E1-mediated viral entry. L0909 exhibits sensitivity to clinical resistant HCV mutants. L0909 displays synergistic effects with clinical HCV drugs. L0909 can be used for the research of hepatitis c virus (HCV) infection .
Cat. No.: HY-107176
CAS No.: 1266548-75-7
Synonyms: (E)-HS-25
Target:
Research Areas:
(E)-Hyzetimibe ((E)-HS-25) (Compound I-1Z) is the trans isomer of Hyzetimibe (HY-107176A), a cholesterol-lowering agent. (E)-Hyzetimibe has cholesterol acyltransferase (ACTA) inhibitory activity, but its cholesterol-lowering effect is relatively weak. (E)-Hyzetimibe can inhibit the entry of hepatitis C virus (HCV) into host cells, and it has a synergistic effect when used in combination with interferon-α. (E)-Hyzetimibe can be used for the study of HCV infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
