IL7R

Isoforms Recommended:	IL-7

By Targets:	Interleukin Related (9) mRNA (1) Small Interfering RNA (siRNA) (3) STAT (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (8) Metabolic Disease (2)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) mRNA (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) Interleukin & Receptors (1) siRNAs (3)

Targets Recommended: Interleukin Related IRAK Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99412

Lusvertikimab 1 Publications Verification OSE-127	Interleukin Related	Cancer
Lusvertikimab (OSE-127) is a humanized *IL7R* monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .

HY-P990774

Verekitug ASP-7266; TRAB-1; UPB-101	Interleukin Related	Inflammation/Immunology
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .

HY-P990023

Bempikibart ADX-914	Interleukin Related	Metabolic Disease Inflammation/Immunology
Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both *IL-7* and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .

HY-P990209

Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) 1 Publications Verification	Interleukin Related	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .

HY-P990911

Crebankitug ZB-168	Interleukin Related	Inflammation/Immunology
HY-P990911 is an *IL7R*-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .

HY-174597

*Human IL7R* mRNA**	mRNA	Inflammation/Immunology
Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.

HY-RS16894

Il7r Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il7r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il7r Mouse Pre-designed siRNA Set A Il7r Mouse Pre-designed siRNA Set A

HY-RS06780

IL7R Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL7R Human Pre-designed siRNA Set A contains three designed siRNAs for IL7R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL7R Human Pre-designed siRNA Set A IL7R Human Pre-designed siRNA Set A

HY-RS23336

Il7r Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Il7r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Il7r Rat Pre-designed siRNA Set A Il7r Rat Pre-designed siRNA Set A

HY-P991720

Tepilukimig	Interleukin Related	Inflammation/Immunology
Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .

HY-P991265

OSE-703	Interleukin Related	Cancer
OSE-703 is a humanized monoclonal antibody inhibitor targeting interleukin-7 receptor α subunit (IL-7Rα). OSE-703 is promising for research of tumors and respiratory diseases .

HY-206870

BP79	Interleukin Related STAT	Inflammation/Immunology
BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks *TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6.* BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .

HY-P992447

QX008N	Interleukin Related	Inflammation/Immunology
QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a K_D value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of *TSLP-TSLPR-IL-7R*α. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99412

Lusvertikimab 1 Publications Verification OSE-127	Interleukin Related	Cancer
Lusvertikimab (OSE-127) is a humanized *IL7R* monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .

HY-P990774

Verekitug ASP-7266; TRAB-1; UPB-101	Interleukin Related	Inflammation/Immunology
Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .

HY-P990023

Bempikibart ADX-914	Interleukin Related	Metabolic Disease Inflammation/Immunology
Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both *IL-7* and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .

HY-P990209

Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) 1 Publications Verification	Interleukin Related	Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .

HY-P990911

Crebankitug ZB-168	Interleukin Related	Inflammation/Immunology
HY-P990911 is an *IL7R*-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .

HY-P991720

Tepilukimig	Interleukin Related	Inflammation/Immunology
Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .

HY-P991265

OSE-703	Interleukin Related	Cancer
OSE-703 is a humanized monoclonal antibody inhibitor targeting interleukin-7 receptor α subunit (IL-7Rα). OSE-703 is promising for research of tumors and respiratory diseases .

HY-P992447

QX008N	Interleukin Related	Inflammation/Immunology
QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a K_D value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of *TSLP-TSLPR-IL-7R*α. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .

Species:	Human (9) Rat (2) Mouse (2) Cynomolgus (1)
Tag:	His (7) Avi (3) Fc (8)
Source:	HEK293 (14)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76436

	CD127/IL-7RA Protein, Mouse (HEK293, His) Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Mouse	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag..

HY-P77425

	CD127/IL-7RA Protein, Cynomolgus (HEK293, His) Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Cynomolgus	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Cynomolgus (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 235 amino acids (M1-P235).

HY-P72536

	CD127/IL-7RA Protein, Mouse (HEK293, Fc) Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127	Mouse	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 219 amino acids (E21-D239).

HY-P72537

	CD127/IL-7RA Protein, Human (HEK293, His) Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127	Human	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 216 amino acids (E21-G236).

HY-P77011

	CD127/IL-7RA Protein, Rat (HEK293, His) Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127	Rat	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Rat (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of 219 amino acids (E21-D239).

HY-P77012

	CD127/IL-7RA Protein, Rat (HEK293, Fc) Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127	Rat	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Rat (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 239 amino acids ((M1-D239).

HY-P704721

	CD127/IL-7RA Protein, Human (HEK293, Fc) rHuCD127; Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Human	HEK293
	CD127/IL-7RA Protein, Human (HEK293, Fc) is the recombinant human-derived CD127/IL-7RA protein, expressed by HEK293, with C-hFc tag.

HY-P704722

	CD127/IL-7RA Protein, Human (HEK293, mFc) rHuCD127; Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Human	HEK293
	CD127/IL-7RA Protein, Human (HEK293, mFc) is the recombinant human-derived CD127/IL-7RA protein, expressed by HEK293, with C-mFc tag.

HY-P7785

	CD127/IL-7RA Protein, Human (HEK293, Fc-His) rHuCD127, C-Fc, His; Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Human	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Human (HEK293, Fc-His) is produced in HEK293 cells with six C-Terminal His-tag and a C-Terminal Fc tag. It consists of 216 amino acids (E21-G236).

HY-P76433

	CD127/IL-7RA Protein, Human (I66T, V138I, HEK293, Fc) Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127	Human	HEK293
	IL-7RA (also known as CD127) is a type 1 membrane glycoprotein folded to bind and mediate the action of IL7 and other alpha helical cytokines. IL-7RA is mainly expressed by cells of the lymphoid lineage. IL-7RA also acts as a receptor for thymic stromal lymphopoietin (TSLP). CD127/IL-7RA Protein, Human (I66T, V138I, HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag..

HY-P78147

	IL-17RA Protein, Human (Biotinylated, HEK293, Fc-Avi) CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-7R; IL-7R-alpha; ILRA	Human	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (Biotinylated, HEK293, Fc-Avi), a Biotinylated IL-17RA protein, is produced in HEK293 cells with a C-Terminal Fc-tag and a C-Terminal Avi-tag.

HY-P78161

	IL-17RA Protein, Human (Biotinylated, HEK293, His-Avi) CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-7R; IL-7R-alpha; ILRA	Human	HEK293
	IL-17RA (Interleukin 17 receptor A), a receptor for IL-17A and IL-17F, is a type I membrane glycoprotein. It is expressed ubiquitously and exhibits a broad tissue distribution, and plays a role in many inflammatory and autoimmune diseases. IL-17RA is a common co-receptor subunit for other members of the IL-17 family. IL-17RA associates with IL-17RC to form a signaling receptor complex for IL-17A and IL-17F. IL-17RA Protein, Human (Biotinylated, HEK293, His-Avi), a Biotinylated IL-17RA protein, is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Avi-tag.

HY-P704255

	CD127/IL-7RA Protein, Human (I66T, V138I, HEK293, mFc)	Human	HEK293
	CD127/IL-7RA Protein, Human (I66T, V138I, HEK293, mFc) is the recombinant human-derived CD127/IL-7RA protein, expressed by HEK293, with C-mFc tag.

HY-P705229

	IL-7RA&IL-2RG Protein, Human (Biotinylated, HEK293, His-Avi) IL-7 R alpha & IL-2 R gamma; IL-7 RA & IL-2 RG	Human	HEK293

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Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4)
Application:	WB (4) FC (2) ELISA (2)
Isotype:	IgG (2) IgG2b (2)
Conjugation:	Non-conjugated (4) Biotin (3)
Clonality:	Monoclonal (1) Monoclonal Antibody (1) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84134

	CD127 Antibody (YA3831) IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha	WB, FC, ELISA	Human
	CD127 Antibody (YA3831) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD127.

HY-P84134A

	CD127 Antibody (YA3831)(PBS only) IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha	WB, FC, ELISA	Human
	CD127 Antibody (YA3831) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD127.

HY-P80593

	CD127 Antibody (YA545) IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127	WB	Human
	CD127 Antibody (YA545) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD127.

HY-P80593A

	CD127 Antibody (YA545)(PBS only) IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127	WB	Human
	CD127 Antibody (YA545) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD127.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-174597

*Human IL7R* mRNA**		mRNA Interleukin & Receptors
Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.

HY-RS16894

Il7r Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Il7r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06780

IL7R Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
IL7R Human Pre-designed siRNA Set A contains three designed siRNAs for IL7R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23336

Il7r Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Il7r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Inhibitory Antibodies

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Antibodies

Oligonucleotides