31 Results for "

IL7R

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "IL7R" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99412
CAS No.: 2375835-91-7
Synonyms: OSE-127

Target:  

Interleukin Related

Research Areas:  

Cancer

Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .
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1
1 Cited Publications
Cat. No.: HY-P990209
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P990023
CAS No.: 2622254-57-1
Synonyms: ADX-914

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .
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Cat. No.: HY-P990911
CAS No.: 2893793-17-2
Synonyms: ZB-168

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HY-P990911 is an IL7R-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .
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Cat. No.: HY-174597
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
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Cat. No.: HY-RS06780
Research Areas:  

Others

IL7R Human Pre-designed siRNA Set A contains three designed siRNAs for IL7R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16894
Research Areas:  

Others

Il7r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23336
Research Areas:  

Others

Il7r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991720
CAS No.: 2985643-31-8

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .
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Cat. No.: HY-P84134A
Synonyms: IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P991265

Target:  

Interleukin Related

Research Areas:  

Cancer

OSE-703 is a humanized monoclonal antibody inhibitor targeting interleukin-7 receptor α subunit (IL-7Rα). OSE-703 is promising for research of tumors and respiratory diseases .
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Cat. No.: HY-P76436
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127
Species:  
Source:  
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Cat. No.: HY-P77425
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127
Species:  
Source:  
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Cat. No.: HY-P84134
Synonyms: IL7R; ILRA; IL7RA; CDW127; IL-7R-alpha

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P72536
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127
Species:  
Source:  
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Cat. No.: HY-P77011
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127
Species:  
Rat
Source:  
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Cat. No.: HY-P77012
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127
Species:  
Rat
Source:  
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Cat. No.: HY-P72537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7 receptor subunit alpha; IL7R; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CD127
Species:  
Source:  
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Cat. No.: HY-P704721
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuCD127; Interleukin-7 receptor subunit alpha; IL7R; IL-7R-alpha; CD127
Species:  
Source:  
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