Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10367 Results for "
Kendall's compound B (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (10367)
10367 Results for "Kendall's compound B (Standard)" in MCE Product Catalog:
819
819 Publications Verification
Synonyms: compound C dihydrochloride; BML-275 dihydrochloride
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a Ki of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).
71
71 Cited Publications
Synonyms: 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
18
18 Cited Publications
Synonyms: γ-Secretase-IN-1
Target:
Research Areas:
Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
16
NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
11
Target:
Research Areas:
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts .
8
8 Cited Publications
Synonyms: C48/80 trihydrochloride
Target:
Research Areas:
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
8
8 Cited Publications
Synonyms: Poly-p-methoxyphenethylmethylamine
Target:
Research Areas:
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways .
7
6
6 Cited Publications
Synonyms: 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E
6
6 Cited Publications
Synonyms: Teijin compound 1 hydrochloride
Target:
Research Areas:
CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
6
6 Cited Publications
Synonyms: Teijin compound 1
Target:
Research Areas:
CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
5
5 Cited Publications
Cat. No.: HY-15142R
CAS No.: 25316-40-9
Synonyms: Hydroxydaunorubicin hydrochloride (Standard); ADR (Standard)
Category:
4
4 Cited Publications
Cat. No.: HY-K1011
MCE 3-Color Prestained Protein Marker (10-190 kDa) is a three-color protein standard with 10 prestained proteins ranging from 10 kDa to 190 kDa. The 250 μL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
3
3 Cited Publications
Synonyms: Diferuloylmethane (Standard); Natural Yellow 3 (Standard); Turmeric yellow (Standard)
3
3 Cited Publications
Synonyms: (E)-Capsaicin (Standard)
3
3 Cited Publications
Synonyms: Deferoxamine B (Standard); Deferriferrioxamine B (Standard); Deferrioxamine (Standard)
Target:
Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Apoptosis Akt Autophagy
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Deferoxamine (Standard) is the analytical standard of Deferoxamine. This product is intended for research and analytical applications. Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 .
3
3 Cited Publications
Cat. No.: HY-17589AR
CAS No.: 54-05-7
Research Areas:
Chloroquine (Standard) is the analytical standard of Chloroquine. This product is intended for research and analytical applications. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM) .
2
2 Cited Publications
Synonyms: Triphenyl compound A
Target:
Research Areas:
TPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells .
2
2 Cited Publications
Synonyms: Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)
2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
