20 Results for "

MADCAM1

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "MADCAM1" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
1
1 Cited Publications
Cat. No.: HY-P990203

Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) is a rat-derived anti-LPAM-1/Integrin α4β7 IgG2a, κ type antibody inhibitor. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) specifically reacts with both chains of the α4β7 heterodimer and blocks the adhesion to immobilized mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) suppresses the proliferation and cytokine secretion of CD8+ T cells. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) decreases Peyer’s patches and follicular B cells in mice. Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) can be used for the researches of inflammation, such as ulcerative colitis [1] .
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1
1 Cited Publications
Cat. No.: HY-P99411
CAS No.: 2098790-40-8
Synonyms: SHP647

Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease [1].
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Cat. No.: HY-P990197

Target:  

L-Selectin

Anti-Mouse MAdCAM-1 Antibody (MECA-367) is an anti-mouse MAdCAM-1 IgG2a monoclonal antibody. Anti-Mouse MAdCAM-1 Antibody (MECA-367) significantly inhibits the migration of pig peripheral blood lymphocytes (PBL) by blocking the function of MAdCAM-1. Anti-Mouse MAdCAM-1 Antibody (MECA-367) selectively inhibits B cell migration to exacerbate inflammation. Anti-Mouse MAdCAM-1 Antibody (MECA-367) can be used for researches on inflammation, metabolic conditions and xenotransplantation such as colitis and diabetes [1] .
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Cat. No.: HY-RS07952
Research Areas:  

Others

MADCAM1 Human Pre-designed siRNA Set A contains three designed siRNAs for MADCAM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25581
Research Areas:  

Others

Madcam1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Madcam1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS19091
Research Areas:  

Others

Madcam1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Madcam1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991807

Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Anti-Mouse MAdCAM-1 Antibody (MECA-89) reacts with mouse MAdCAM-1. Anti-Mouse MAdCAM-1 Antibody (MECA-89) blocks the interaction of MAdCAM-1 with its receptor in vivo and in vitro. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) [1].
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Cat. No.: HY-P77748
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MADCAM-1; MADCAM1; MACAM1
Species:  
Source:  
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Cat. No.: HY-P705263
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MADCAM-1; MADCAM1; MACAM1
Species:  
Source:  
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Cat. No.: HY-177961
CAS No.: 2417307-52-7
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

α4β7 Integrin-IN-1 (Example 356) is a potent inhibitor of α4β7 integrin (integrin). Its ability to block the interaction between α4β7 integrin and MadCAM-1 (EC50) is 0.05 nM. α4β7 Integrin-IN-1 can be used for the study of inflammatory bowel disease [1].
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Cat. No.: HY-P70852
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: hMADCAM-1; MACAM1; MADCAM1; MADCAM-1; mucosal addressin cell adhesion molecule 1
Species:  
Source:  
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Cat. No.: HY-P704773
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: hMADCAM-1; MACAM1; MADCAM1; MADCAM-1; mucosal addressin cell adhesion molecule 1
Species:  
Source:  
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Cat. No.: HY-P705058
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: hMADCAM-1; MACAM1; MADCAM1; MADCAM-1; mucosal addressin cell adhesion molecule 1
Species:  
Source:  
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Cat. No.: HY-P705198
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: hMADCAM-1; MACAM1; MADCAM1; MADCAM-1; mucosal addressin cell adhesion molecule 1
Species:  
Source:  
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Cat. No.: HY-P72397
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: hMADCAM-1; MACAM1; MADCAM1; MADCAM-1; mucosal addressin cell adhesion molecule 1
Species:  
Source:  
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Cat. No.: HY-P82999
Synonyms: MACAM1; MADCAM1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-159179
CAS No.: 863226-74-8
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

α4 integrin receptor antagonist 3 (Compound 11) is an orally active α4integrin receptor antagonist. α4 integrin receptor antagonist 3 can inhibit the adhesion of K562 cells mediated by the interaction between α4β1/VCAM-1 and α4β7/MAdCAM-1, with IC50 values of 130 nM and 2 nM, respectively. α4 integrin receptor antagonist 3 has the potential to be used in the study of dextran sulfate sodium (DSS) colitis mouse model [1].
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Cat. No.: HY-P71818
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Addressin mucosal; hMADCAM 1 ; hMADCAM-1; MACAM1
Species:  
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Cat. No.: HY-171216
CAS No.: 278598-52-0
Target:  

Integrin

Research Areas:  

Neurological Disease

GW559090 is a selective, competitive, and high-affinity α4 integrin antagonist with a Kd of 0.19 nM for α4β1. GW559090 can effectively block the binding of α4β1 to vascular cell adhesion molecule 1 (VCAM-1) and fibronectin with IC50 values of 7.72 and 8.04 nM. GW559090 also inhibits the interaction between α4β7 and mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (IC50 = 23 nM). GW559090 can inhibit inflammatory infiltration in the eyes, repair the corneal barrier and restore the function of goblet cells. GW559090 can be used for research of Sjögren's syndrome associated dry eye [1].
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Cat. No.: HY-P704774
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Addressin mucosal; hMADCAM 1 ; hMADCAM-1; MACAM1
Species:  
Source:  
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