15 Results for "

MASP2

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "MASP2" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
3
3 Cited Publications
Cat. No.: HY-P0227
CAS No.: 168482-23-3
Target:  

Melanocortin Receptor

Research Areas:  

Metabolic Disease

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.
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1 Cited Publications
Cat. No.: HY-P99376
CAS No.: 2108782-45-0
Synonyms: OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)

Target:  

SARS-CoV

Research Areas:  

Infection

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2 .
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Cat. No.: HY-P991312

Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

CM-338 is a human monoclonal antibody (mAb) targeting MASP2. CM-338 can be used in IgA nephropathy research.
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Cat. No.: HY-172090
CAS No.: 3103336-29-1
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

MASP-2-IN-1 (Compound 77) is a selective MASP-2 inhibitor with an IC50 of 0.0114 μM, and an IC50 of 13.2 μM against MASP-3. MASP-2-IN-1 inhibits the catalytic activity of MASP-2 in the lectin complement pathway. MASP-2-IN-1 is applicable to the research of immune diseases .
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Cat. No.: HY-RS17231
Research Areas:  

Others

Masp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Masp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS08160
Research Areas:  

Others

MASP2 Human Pre-designed siRNA Set A contains three designed siRNAs for MASP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1208
CAS No.: 667430-81-1
Target:  

Melanocortin Receptor

Research Areas:  

Inflammation/Immunology

PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo [2].
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Cat. No.: HY-RS23684
Research Areas:  

Others

Masp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Masp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P77799
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MAP19; MASP-2; MASP1P1; sMap
Species:  
Source:  
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Cat. No.: HY-P78005
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MAP19; MASP-2; MASP1P1; sMap
Species:  
Source:  
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Cat. No.: HY-P77800
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MAP19; MASP-2; MASP1P1; sMap
Species:  
Source:  
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Cat. No.: HY-P77801
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MAP19; MASP-2; MASP1P1; sMap
Species:  
Rat
Source:  
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Cat. No.: HY-P77802
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: MAP19; MASP-2; MASP1P1; sMap
Species:  
Rat
Source:  
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Cat. No.: HY-E70390
Synonyms: MASP-2, c1 esterase, c1-esterase
Target:  

Wnt

C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .
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Cat. No.: HY-P992463

Target:  

Ser/Thr Protease

Research Areas:  

Endocrinology

SHR-2010 is a fully humanized monoclonal antibody targeting MASP-2. SHR-2010 selectively inhibits lectin pathway activation without affecting classical or alternative complement pathways. SHR-2010 can be used for the research of IgA nephropathy .
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