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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
MCD
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "MCD" in MCE Product Catalog:
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1 Cited Publications
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CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases .
Cat. No.: HY-P99656
CAS No.: 1906205-76-2
Synonyms: MCDS0593A
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A3051 is a potent and orally active inhibtor of CXXC5-DVL extracted from patent WO2020079569, has an IC50 of 63.06 nM. A3334 can be used for the research of high fat diet (HFD)-induced and methionine-choline deficient diet (MCD)-induced phenotypes such as obesity, diabetes, and NASH .
Cat. No.: HY-W015860
CAS No.: 2687-25-4
Synonyms: Tolylene-2,3-diamine
3-Methylbenzene-1,2-diamine (Tolylene-2,3-diamine) is a CD44 hyaluronic acid-binding domain ligand, with a Kd of 8.5 mM for hCD44 HABD and a Kd of 6.4 mM for mCD44 HABD. 3-Methylbenzene-1,2-diamine acts as a non-inhibitor that does not interfere with the binding of CD44 HABD to polymeric hyaluronic acid in vitro .
Cat. No.: HY-RS08506
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MLYCD Human Pre-designed siRNA Set A contains three designed siRNAs for MLYCD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28168
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Mlycd Rat Pre-designed siRNA Set A contains three designed siRNAs for Mlycd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Anti-NASH agent 1 (compound 3d)，a derivative of Elafibranor (HY-16737)，is a potent agonist of PPAR-α/δ，targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia，liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect .
Cat. No.: HY-P11264
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Cat. No.: HY-RS08831
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MUC1 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701981
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MLYCD; Malonyl-CoA decarboxylase; mitochondrial; MCD
Cat. No.: HY-P701982
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MLYCD; Malonyl-CoA decarboxylase; mitochondrial; MCD
Cat. No.: HY-RS21650
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Mlycd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mlycd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-171172
CAS No.: 2493080-16-1
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GSC-718 is a synthetic sialoside and is a ligand mimic for CD22. GSC-718 is a potent CD22 inhibitor with an IC50 of 0.161μM for mCD22. GSC-718 promote the proliferation of B cells and enhance antibody production. GSC-718 can be used for researches of B-cell lymphoma and rheumatoid arthritis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
