35 Results for "

MCD

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "MCD" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P9956
CAS No.: 541502-14-1
Synonyms: CNTO-328

Target:  

Interleukin Related

Research Areas:  

Cancer

Siltuximab is an anti-IL-6 (interleukin-6) monoclonal antibody, and shows antitumor activity. Siltuximab can be used in Multicentric Castleman's Disease (MCD) and COVID-19 research .
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1
1 Cited Publications
Cat. No.: HY-125748
CAS No.: 902146-11-6
Purity:  99.4%
Research Areas:  

Cardiovascular Disease

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases .
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Cat. No.: HY-P99656
CAS No.: 1906205-76-2
Synonyms: MCDS0593A

Target:  

ADC Antibodies

Research Areas:  

Cancer

Iladatuzumab (MCDS0593A) is a humanized IgG1 anti-human CD79B monoclonal antibody. Iladatuzumab can be used to synthesize antibody-drug conjugates (ADC) Iladatuzumab vedotin (DCDS0780A; HY-P99657), which has the potential for B-cell non-Hodgkin lymphoma (B-NHL) research .
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Cat. No.: HY-128421
CAS No.: 505-52-2
Purity:  99.93%
Synonyms: Brassylic Acid
Tridecanedioic acid (Brassylic Acid) is a long-chain fatty acid and an endogenous serum metabolite. Tridecanedioic acid is positively correlated with the intestinal genus Tuzzerella in non-alcoholic steatohepatitis (NASH) mice fed a MCD diet. Tridecanedioic acid accumulates at high levels in Brassica napus germplasm tolerant to Plutella xylostella (diamondback moth), thereby participating in plant defense. Tridecanedioic acid can be used in studies related to Plutella xylostella infestation .
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Cat. No.: HY-131448
CAS No.: 854171-31-6
Purity:  99.64%
Target:  

β-catenin Wnt

Research Areas:  

Metabolic Disease

A3051 is a potent and orally active inhibtor of CXXC5-DVL extracted from patent WO2020079569, has an IC50 of 63.06 nM. A3334 can be used for the research of high fat diet (HFD)-induced and methionine-choline deficient diet (MCD)-induced phenotypes such as obesity, diabetes, and NASH .
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Cat. No.: HY-W015860
CAS No.: 2687-25-4
Synonyms: Tolylene-2,3-diamine
Target:  

CD44

Research Areas:  

Others

3-Methylbenzene-1,2-diamine (Tolylene-2,3-diamine) is a CD44 hyaluronic acid-binding domain ligand, with a Kd of 8.5 mM for hCD44 HABD and a Kd of 6.4 mM for mCD44 HABD. 3-Methylbenzene-1,2-diamine acts as a non-inhibitor that does not interfere with the binding of CD44 HABD to polymeric hyaluronic acid in vitro .
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Cat. No.: HY-RS08506
Research Areas:  

Others

MLYCD Human Pre-designed siRNA Set A contains three designed siRNAs for MLYCD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS28168
Research Areas:  

Others

Mlycd Rat Pre-designed siRNA Set A contains three designed siRNAs for Mlycd gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-146759
CAS No.: 3032667-17-4
Target:  

CD73

Research Areas:  

Cancer

ZM514 is a potent CD73 inhibitor with IC50s of 1.39 μM and 14.65 μM for hCD73 and mCD73, respectively. ZM514 has low cytotoxicity. ZM514 can be used for researching anticancer .
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Cat. No.: HY-175319
Target:  

CD73

Research Areas:  

Cancer

CD73-IN-21 (Compound 12f) is an Ecto-5′-nucleotidase (CD73) inhibitor with Kis of 20 and 302  nM for hCD73 and mCD73, respectively. CD73-IN-21 can be used for cancers like breast cancer research .
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Cat. No.: HY-155525
CAS No.: 2409685-41-0
Purity:  98.49%
Target:  

PPAR

Anti-NASH agent 1 (compound 3d),a derivative of Elafibranor (HY-16737),is a potent agonist of PPAR-α/δ,targeting to nonalcoholic steatohepatitis (NASH). Anti-NASH agent 1 (3-10 mg/kg; 4 weeks) improves hyperlipidemia,liver fat degeneration and liver inflammation in Methionine-choline deficiency (MCD) induced NASH mice model. Anti-NASH agent 1 shows low liver toxicity and potent liver protection effect .
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Cat. No.: HY-P11264
Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 (HY-Y0298)-induce and MCD-diet-induce acute liver inflammation and fibrosis .
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Cat. No.: HY-RS08831
Research Areas:  

Others

MUC1 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P701981
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MLYCD; Malonyl-CoA Decarboxylase, Mitochondrial; Malonyl-CoA Decarboxylase; HMCD; MCD; Malonyl Coenzyme A Decarboxylase
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701982
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MLYCD; Malonyl-CoA Decarboxylase, Mitochondrial; Malonyl-CoA Decarboxylase; HMCD; MCD; Malonyl Coenzyme A Decarboxylase
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-RS21650
Research Areas:  

Others

Mlycd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mlycd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84120
Synonyms: MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84120A
Synonyms: MUC1; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P83849
Synonyms: HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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Cat. No.: HY-P83849A
Synonyms: HR21; MCD1; NXP1; SCC1; CDLS4; hHR21; HRAD21

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Rat, Monkey

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