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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
MLC
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "MLC" in MCE Product Catalog:
1
1 Cited Publications
HA-100 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor .
Cat. No.: HY-156397
Purity: 99.42%
HTH-02-006 is a NUAK2 inhibitor, with an IC50 value of 126 nM. HTH-02-006 inhibits NUAK2-mediated signaling by reducing phosphorylation of its substrate MYPT1 at S445 and downstream MLC. HTH-02-006 shows growth inhibitory efficacy in YAP-high cancer cells (HuCCT-1, SNU475). HTH-02-006 significantly suppresses YAP-induced hepatomegaly (reduced liver/body weight ratio) in TetO-YAP S127A transgenic mice and demonstrates significant anti-tumor efficacy in mice bearing HMVP2 prostate cancer allografts. HTH-02-006 can be used for the study of liver cancer and prostate cancer .
Cat. No.: HY-RS08485
Target:
Research Areas:
MLC1 Human Pre-designed siRNA Set A contains three designed siRNAs for MLC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-12880
CAS No.: 210297-47-5
HA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor .
Cat. No.: HY-108554
CAS No.: 1052076-77-3
Research Areas:
Q94 hydrochloride, a selective PAR1 antagonist (IC50=916 nM), can selectively block PAR1/Gαq interaction and signalling. Q94 hydrochloride blocks PAR1-mediated increases in both CCL2 mRNA and protein levels in a dose-dependent manner. Q94 hydrochloride also completely blocks thrombin-induced ERK1/2 and MLC phosphorylation .
Cat. No.: HY-N16519
CAS No.: 154905-69-8
Category:
Target:
Cat. No.: HY-100984A
CAS No.: 141543-63-7
HA-100 hydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 hydrochloride also used as a ROCK inhibitor .
Cat. No.: HY-P704107
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MRLC2; MYLC2B; MLC-2A (MLC-2); Myosin regulatory light chain 2-B, smooth muscle isoform; Myosin regulatory light chain 20 kDa (MLC20); Myosin regulatory light chain MRLC2; SHUJUN-1
Cat. No.: HY-P87027
Synonyms: 20 kDa myosin light chain antibody; Human 20kDa myosin light chain (MLC2) mRNA complete cds antibody; LC20 antibody; MGC3505 antibody; MLC 2 antibody; MLC-2C antibody; MLC2 antibody; MLY 9 antibody; MRLC1 antibody; MYL9 antibody; 20 kDa myosin light chain antibody; Human 20kDa myosin light chain (MLC2) mRNA complete cds antibody; LC20 antibody; MGC3505 antibody; MLC 2 antibody; MLC-2C antibody; MLC2 antibody; MLY 9 antibody; MRLC1 antibody; MYL9 antibody; MYL9_HUMAN antibody; Myosin light chain 9 regulatory antibody; Myosin light polypeptide 9 regulatory antibody; myosin regulatory light chain 1 antibody; Myosin regulatory light chain 2 antibody; Myosin regulatory light chain 2 smooth muscle isoform antibody; Myosin regulatory light chain 9 antibody; Myosin regulatory light chain MRLC1 antibody; Myosin regulatory light polypeptide 9 antibody; Myosin RLC antibody; Myosin vascular smooth muscle light chain 2 antibody; MYRL2 antibody; OTTHUMP00000030857 antibody; smooth muscle isoform antibody;
Cat. No.: HY-100984R
CAS No.: 84468-24-6
HA-100 (Standard) is the analytical standard of HA-100 (HY-100984). This product is intended for research and analytical applications. HA-100 is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 also used as a ROCK inhibitor .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
